Author(s): Saravanan J, Suneetha V

Email(s): vsuneetha@vit.ac.in

DOI: 10.5958/0974-360X.2017.00330.4   

Address: Saravanan J1, Suneetha V2*
1Anthem Biosciences Private Limited, Bangalore.
2School of Biosciences and Technology, VIT University, Vellore 632014, Tamil Nadu India
*Corresponding Author

Published In:   Volume - 10,      Issue - 6,     Year - 2017


ABSTRACT:
Biotransformation of chiral intermediates using micro-organism has widely used in many industries due to green technology and cost effectiveness. Moreover, Enzymes are highly ‘Chemo-, regio-, and enantio-selective’ in nature. From decades, bio-reduction performed using whole cells and free enzymes for the production of chiral alcohols. Some recent developments in the area of fermentative biotransformation processes for the reduction of Keto- sulfone to hydroxy sulfone and Lipitor intermediate are reviewed and importance of microbial mediated asymmetric synthesis of chiral alcohols are highlighted for the future perspective.


Cite this article:
Saravanan J, Suneetha V. Asymmetric Synthesis of Chiral Alcohols for API Production using Microorganisms - A Mini Review. Research J. Pharm. and Tech. 2017; 10(6): 1881-1885. doi: 10.5958/0974-360X.2017.00330.4

Cite(Electronic):
Saravanan J, Suneetha V. Asymmetric Synthesis of Chiral Alcohols for API Production using Microorganisms - A Mini Review. Research J. Pharm. and Tech. 2017; 10(6): 1881-1885. doi: 10.5958/0974-360X.2017.00330.4   Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2017-10-6-54


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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