ABSTRACT:
Myxobacteria being a gram -ve, rod-shaped, slow growing bacteria along with omnipresent producer of bioactive compound with anti-bacterial, anti-fungal, anti-viral as well as anti-tumor activity, has attained the attention of many researchers. Diverse areas and habitats are being explored for isolating this bacterium but, till date there is no reported documentation of this bacteria from the Himachal region. In this study, the focus was given on isolating the Myxobacteria from Himachal region and to evaluate its anti-microbial activity of isolated strains. The pure strains were isolated from the soil sample by visualizing the unusual properties of Myxobacteria, following the purification method, recognition and characterization on the basis of colony formation, observing the fruiting bodies under the stereomicroscope. After that cell extract as well as supernatant of the isolated strain was assessed for the presence of anti-microbial agent. From the obtained result, it was found that isolated strains were able to inhibit the growth of test organism such as E. coli, B. subtilis, Clostridium acetobutylicum, Stenotrophomonas maltophilia, Pseudomonas sp., and Trichoderma reesei.