Author(s):
K. Ishwar Bhat, Apoorva A, Abhishek Kumar, Pankaj Kumar
Email(s):
abhi12bunty@gmail.com
DOI:
10.5958/0974-360X.2018.00987.3 
Address:
K. Ishwar Bhat, Apoorva A, Abhishek Kumar, Pankaj Kumar
Department of Pharmaceutical Chemistry, NGSM Institute of Pharmaceutical Sciences, NITTE (Deemed to be University), Paneer, Deralakatte-575018, Mangalore, Karnataka.
*Corresponding Author
Published In:
Volume - 11,
Issue - 12,
Year - 2018
ABSTRACT:
A series of new 4-thiazolidinone derivatives were synthesized by reacting various coumarinyl schiff bases with thioglycollic acid. The intermediate coumarinyl schiff bases were synthesized by reacting 4-hydroxyl coumarin with various substituted anilines in alcohol medium. All the newly synthesized compounds were assigned on the basis of IR, 1H NMR and mass spectral data. All the newly synthesized compounds were evaluated for in-vitro antioxidant activities like DPPH, nitric oxide and hydrogen peroxide radical scavenging assay models. Most of the synthesised compounds showed good antioxidant activity.
Cite this article:
K. Ishwar Bhat, Apoorva A, Abhishek Kumar, Pankaj Kumar. Synthesis and Antioxidant Activity of Some New Coumarin Incorporated 4-Thiazolidinone Derivatives. Research J. Pharm. and Tech 2018; 11(12): 5408-5412. doi: 10.5958/0974-360X.2018.00987.3
Cite(Electronic):
K. Ishwar Bhat, Apoorva A, Abhishek Kumar, Pankaj Kumar. Synthesis and Antioxidant Activity of Some New Coumarin Incorporated 4-Thiazolidinone Derivatives. Research J. Pharm. and Tech 2018; 11(12): 5408-5412. doi: 10.5958/0974-360X.2018.00987.3 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2018-11-12-36