Author(s):
Shanmuga Sundaram Rajagopal, Anila A Varghese, Krishnaveni Kandasamy, Bhavatharini Sukumaran
Email(s):
malshan34@gmail.com
DOI:
10.5958/0974-360X.2018.01029.6 
Address:
Shanmuga Sundaram Rajagopal, Anila A Varghese, Krishnaveni Kandasamy, Bhavatharini Sukumaran
Department of Pharmacology, Department of Pharmacy Practice, J.K.K Nattraja College of Pharmacy, Komarapalayam, Tamilnadu, India
*Corresponding Author
Published In:
Volume - 11,
Issue - 12,
Year - 2018
ABSTRACT:
Pharmacogenetic polymorphism results from the mutations in a Cytochrome P450 (CYP) gene leading to functional alterations, such as increased or decreased activity and occurs at a frequency of at least one percent in a population. At present clinical situation drug clearance and inter-individual variation in drug response is a usual and complex problem. In this clinical review there is a fast update on pharmacogenetics and genetic polymorphism of CYP enzymes in Indian population.
Cite this article:
Shanmuga Sundaram Rajagopal, Anila A Varghese, Krishnaveni Kandasamy, Bhavatharini Sukumaran. Pharmacogenetics and Genetic Polymorphism of CYP Enzymes in Indian Population: A Clinical Review. Research J. Pharm. and Tech 2018; 11(12): 5681-5686. doi: 10.5958/0974-360X.2018.01029.6
Cite(Electronic):
Shanmuga Sundaram Rajagopal, Anila A Varghese, Krishnaveni Kandasamy, Bhavatharini Sukumaran. Pharmacogenetics and Genetic Polymorphism of CYP Enzymes in Indian Population: A Clinical Review. Research J. Pharm. and Tech 2018; 11(12): 5681-5686. doi: 10.5958/0974-360X.2018.01029.6 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2018-11-12-78