Author(s):
K. Ishwar Bhat, Abhishek Kumar
Email(s):
abhi12bunty@gmail.com
DOI:
10.5958/0974-360X.2018.00367.0
Address:
K. Ishwar Bhat1, Abhishek Kumar2*
1Department of Pharmaceutical Chemistry, NGSM Institute of Pharmaceutical Sciences, Nitte (Deemed to be University), Paneer, Deralakatte-575018, Mangalore, Karnataka.
2Assistant Professor, (Department of Pharmaceutical Chemistry) NGSM Institute of Pharmaceutical Sciences Paneer, Deralakatte, Mangalore 575018, Karnataka, India.
*Corresponding Author
Published In:
Volume - 11,
Issue - 5,
Year - 2018
ABSTRACT:
A series of novel pyrazoline derivatives have been synthesized known for their wide clinical applications such as antibacterial, anticancer, antifungal and antitubercular agents. Chalcones are known to exhibit interesting pharmacological activities like anti-inflammatory, antileishmanial, antibacterial, antitumor, antimalarial and antitubercular activity. A series of pyrazoline derivatives [Substituted 1,5-diphenyl-3-(m-tolyl)-4,5-dihydro-1H-pyrazole] were prepared from chalcones by the reported method, characterized by IR, 1H NMR and mass spectra. The synthesized compounds were evaluated for antioxidant activity studies. Most of the compounds have exhibited promising antioxidant activities.
Cite this article:
K. Ishwar Bhat, Abhishek Kumar. Pyrazolines as Potent Antioxidant Agents. Research J. Pharm. and Tech 2018; 11(5):1978-1980. doi: 10.5958/0974-360X.2018.00367.0
Cite(Electronic):
K. Ishwar Bhat, Abhishek Kumar. Pyrazolines as Potent Antioxidant Agents. Research J. Pharm. and Tech 2018; 11(5):1978-1980. doi: 10.5958/0974-360X.2018.00367.0 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2018-11-5-52