Author(s):
Salah Eddine Rahmani, Mokhtar Lahrech
Email(s):
rahmanidz@yahoo.fr
DOI:
10.5958/0974-360X.2018.00754.0 
Address:
Salah Eddine Rahmani1*, Mokhtar Lahrech2
1Laboratory of Organic Chemistry and Natural Substances, University of Djelfa, 17000, ALGERIA.
2Department of Biology, Faculty of Life and Natural Sciences, University of Djelfa, 17000, ALGERIA.
*Corresponding Author
Published In:
Volume - 11,
Issue - 9,
Year - 2018
ABSTRACT:
In our work, a series of substituted hydrazone Schiff’s bases of N-benzylideneacetohydrazide 2-(1H-benzo[d] [1,2,3] triazol-1-yl)- (B3-B12) were synthesized from the benzotriazole hydrazide and with the use of various aromatic aldehydes. The structure of the synthesized compounds was confirmed by IR, 1HNMR and Mass spectra. All the compounds were screened for in vitro antioxidant activity by DPPH scavenging and FRAP assay. The results show that all the compounds have significant antioxidant activity. Compounds substituted with electron donating groups like methoxy and hydroxyl showed higher antioxidant activity.
Cite this article:
Salah Eddine Rahmani, Mokhtar Lahrech. Evaluation of the Antioxidant Activity of some Hydrazone Schiff’s bases bearing Benzotriazole Moiety. Research J. Pharm. and Tech 2018; 11(9): 4104-4107. doi: 10.5958/0974-360X.2018.00754.0
Cite(Electronic):
Salah Eddine Rahmani, Mokhtar Lahrech. Evaluation of the Antioxidant Activity of some Hydrazone Schiff’s bases bearing Benzotriazole Moiety. Research J. Pharm. and Tech 2018; 11(9): 4104-4107. doi: 10.5958/0974-360X.2018.00754.0 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2018-11-9-69