ABSTRACT:
The proposed method was carried out based on the interaction between the mefenamic acid and barium chloride in the basic medium to form a white precipitate of the binary ions complex. The turbidity values were determined by measuring the reflection of the incident light which is collided with the deposited particles at 0-1800 using Ayah 6SX1-T-2D solar cell CFIA. The plotted calibration graph has a linear range of (2-50 mmol/L) and the value of correlation coefficient is 0.9986 whereas the linearity percentage (r2%) is 99.71%, respectively. Detection limit (L.O.D) (S/N=3) = 240ng/sample of the gradual reduction of the lower concentration in linear dynamics ranging from the calibration graph. The proposed method was successfully applied for the quantitative determination of mefenamic acid (MFA) in three types of pharmaceutical samples. The proposed method was compared with the traditional method by using the standard addition (SA) method. The T test is used to show that there is no significant difference between the proposed method and the formal method with 95% confidence therefore, this method has suggested a new line for mefenamic acid determination.