ABSTRACT:
Zinc is well known for its physical and optical properties. Today, nanomedicine gain importance for their therapeutic purposes. Zinc oxide nanoparticles gained the attention of world for their excellent physical, chemical and biological properties. The main objective of the current study was to synthesis the zinc oxide nanoparticles (ZnO NPs) in a cost effective biological method. The aqueous extract of Luffa acutangula peel was used to synthesis Zinc oxide nanoparticles. The synthesized zinc oxide nanoparticles were confirmed by ultra violet visible spectroscopy band obtained at 377 nm. The Fourier Transform Infra Red Spectroscopy was performed to identify the functional groups present. Also the scanning electron microscope (SEM) was used for the determination of shape of the zinc oxide nanoparticles and it was found to be spherical in shape. The characterized zinc oxide nanoparticles were used to evaluate their antioxidant activity by 2, 2-di phenyl picryl hydrazyl (DPPH) assay. It showed the significant antioxidant activity with IC50 value of 134.12µg/ml. It could be seen that zinc oxide nanoparticles thus prepared had the antioxidant activity and was one of the best candidate for this effect. Further investigations are necessary for chemical characterization of the active compounds and more comprehensive biological assays for their activity.