ABSTRACT:
In this article, some new heterocyclic derivatives, for example pyrimidine and pyrazoles were synthesized by reaction vanillin with paracetamol utilizing KOH as a catalyst to synthase 3-(4-hydroxy-3-methoxyphenyl)-N-(4-hydroxyphenyl)acrylamide(1).The compound (1) on react with Sodium azide, hydrazine, urea, and thiourea in the existence of acetic acid or KOH and ethanol as a catalyst to give (2,3,4,5) compounds. The reaction monitors by TLC. All synthesized compounds have been distinguished by melting point, IR, 1H.NMR spectroscopy.
Cite this article:
Hutham Abd Ali Abd Al Hussain, Sawsan Khudhair Abbas. Synthesis and Characterization New Heterocyclic Compounds derivatives from Vanillin. Research J. Pharm. and Tech. 2019; 12(4):1943-1946. doi: 10.5958/0974-360X.2019.00325.1
Cite(Electronic):
Hutham Abd Ali Abd Al Hussain, Sawsan Khudhair Abbas. Synthesis and Characterization New Heterocyclic Compounds derivatives from Vanillin. Research J. Pharm. and Tech. 2019; 12(4):1943-1946. doi: 10.5958/0974-360X.2019.00325.1 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2019-12-4-80