Research Journal of Pharmacy and Technology

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0974-360X (Online)
0974-3618 (Print)


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Role of Copper (II) ion, in the Photochemical and Photosensitizing Properties of Zomepirac

Author(s): Waseem Ahmad

Email(s): waseemahmad8@gmail.com

DOI: 10.5958/0974-360X.2019.00395.0   

Address: Waseem Ahmad*
Organic Chemistry Section, Department of Chemistry, Uttaranchal University, Dehradun 248001, India
*Corresponding Author

Published In:   Volume - 12,      Issue - 5,     Year - 2019

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ABSTRACT:
A solution of zomepirac in methanol was irradiated with UVA light (?=254) in Rayonet photochemical reactor. Photoproducts obtained were isolated and characterized on the basis of IR, 1H NMR, 13C NMR spectroscopy and elemental analysis. Photochemical behavior of zomepirac was also studied in presence of copper (ii) ions. Copper at very low levels of concentration, modulates the distribution of zomepirac stable photoproducts as well as inhibits the DNA cleavage photo induced by the drug, via a highly efficient electron transfer process with the main transient species generated in the zomepirac photolysis.


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Cite this article:
Waseem Ahmad. Role of Copper (II) ion, in the Photochemical and Photosensitizing Properties of Zomepirac. Research J. Pharm. and Tech. 2019; 12(5):2359-2362. doi: 10.5958/0974-360X.2019.00395.0

Cite(Electronic):
Waseem Ahmad. Role of Copper (II) ion, in the Photochemical and Photosensitizing Properties of Zomepirac. Research J. Pharm. and Tech. 2019; 12(5):2359-2362. doi: 10.5958/0974-360X.2019.00395.0   Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2019-12-5-54


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
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