Author(s):
G. S. Joshi, A. J. Asnani
Email(s):
jsgunja@gmail.com , ajasnani7@gmail.com
DOI:
10.5958/0974-360X.2019.00481.5
Address:
G. S. Joshi*, A. J. Asnani
1Researcher, Dadasaheb Balpande College of Pharmacy, Nagpur – 440037, India.
2Professor, J. L. Chaturvedi College of Pharmacy, Nagpur – 440016, India.
*Corresponding Author
Published In:
Volume - 12,
Issue - 6,
Year - 2019
ABSTRACT:
Some new hydrazino group substituted benzothiazole derivatives have been synthesized and their characterization were identified on the basis of melting point range, Rf values, IR and 1H NMR spectral analysis. The derivatives were screened for anti-inflammatory (Carrageenan-induced paw edema test in rats), analgesic (Hot plate method) and anticonvulsant (Electric shock method) activities inflammatory, analgesic and anticonvulsant activities. The derivatives exhibited significant to moderate anti-inflammatory analgesic and anticonvulsant activities.
Cite this article:
G. S. Joshi, A. J. Asnani. Synthesis and Pharmacological Activity of Some 2-[6-(Phenyl) 2-Thio 1,3-Oxazin-3yl] Amino Benzothiazole Derivatives. Research J. Pharm. and Tech. 2019; 12(6): 2857 -2861. doi: 10.5958/0974-360X.2019.00481.5
Cite(Electronic):
G. S. Joshi, A. J. Asnani. Synthesis and Pharmacological Activity of Some 2-[6-(Phenyl) 2-Thio 1,3-Oxazin-3yl] Amino Benzothiazole Derivatives. Research J. Pharm. and Tech. 2019; 12(6): 2857 -2861. doi: 10.5958/0974-360X.2019.00481.5 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2019-12-6-44