ABSTRACT:
Background: Cervicitis is inflammation of cervical, it’s associated with most commonly of sexually transmitted viruses such as human papilloma virus and herpes simplex virus. Objective: To estimate the fre¬quency of infection with human papilloma virus -16 and herpes simplex virus-2 in women with cervicitis and related with age and severity in Baghdad city. Patients and Methods: Retrospective study was conducted in 50 formalin-fixed paraffin embedded tissues from women with chronic cervicitis were collected from the archives of the Department of Pathology, Teaching Laboratories in Baghdad Medical City during the period from February 2018 till April 2018. Immunohistochemical staining of human papilloma virus -16 and herpes simplex virus -2 were determined in study group. Results: The expression of human papilloma virus -16 and herpes simplex virus -2 in women tissues with chronic cervicitis was 40% (20 out of 50). Most positive viral cases 10(50%) and 12(60%) were recorded in age group (20-35) years respectively; non-significant differences was noticed between viral infection and age of patients, majority of women were CIN1 44(88%) while other in CIN2 6(12%) also non-significant differences was found between viral infection and stage of chronic cervicitis. Conclusion: Infection rate of human papilloma infection - 16 and herpes simplex infection - 2 in this investigation were lower than different reports from various nations, this could be connected with the social conduct of ladies around there, where they generally have just a single accomplice for the duration of their life.