Author(s):
Kedar M.S, Shirbhate M.P, Rajani Chauhan, Suman Sharma, Amrita Verma
Email(s):
17vedant17@gmail.com
DOI:
10.5958/0974-360X.2020.00069.4
Address:
Ms. Kedar M.S1, Dr. Shirbhate M.P2, Dr. Rajani Chauhan3, Dr. Suman Sharma4, Dr. Amrita Verma5
1Lecturer, Amrutvahini Institute of Pharmacy, Sangamner
2Principal, Amrutvahini Institute of Pharmacy, Sangamner
3Associate Professor, Banasthali Vidhyapith Department of Pharmacy, Rajasthan
4Assistant Professor, Banasthali Vidhyapith Department of Pharmacy, Rajasthan
5Assistant Professor, Graphic Era Hill University, Bhimtal, Nainital
*Corresponding Author
Published In:
Volume - 13,
Issue - 1,
Year - 2020
ABSTRACT:
Pyrazoles are also a class of compounds that have the ring C3N2 with adjacent nitrogen atoms.[2] Notable drugs containing a pyrazole ring are celecoxib (Celebrex) and the anabolic steroid stanozolol. Chalcone is an aromatic ketone and an enone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones or chalconoids. Chalcones (1,3-diaryl propenones), a family of small molecules that are naturally abundant in edible plants, have been found to have antitumor properties for specific cancer cell lines and to interfere in each step of carcinogenesis, including apoptosis.
Cite this article:
Kedar M.S, Shirbhate M.P, Rajani Chauhan, Suman Sharma, Amrita Verma. Design Synthesis and Evaluation of Anticancer Pyrazole Derivatives of Chalcone Scaffold. Research J. Pharm. and Tech. 2020; 13(1): 342-346. doi: 10.5958/0974-360X.2020.00069.4
Cite(Electronic):
Kedar M.S, Shirbhate M.P, Rajani Chauhan, Suman Sharma, Amrita Verma. Design Synthesis and Evaluation of Anticancer Pyrazole Derivatives of Chalcone Scaffold. Research J. Pharm. and Tech. 2020; 13(1): 342-346. doi: 10.5958/0974-360X.2020.00069.4 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2020-13-1-69