ABSTRACT:
Allium hirtifolium (A. hirtifolium), a member of the Amaryllidaceae family, is generally known as Persian shallot. It usually grows in hilly areas and took place in most of Persian cuisine. The parts of A. hirtifolium used in folk medicine and recently the constituents have been identified and documented. The compounds present in A. hirtifolium possess various beneficial biological effects such as antibacterial, antioxidant and antidiabetic. Naringenin is the major compound found among all flavonoids with diverse pharmacological activities. In addition, the constituents present in this plant plays various roles in modulating signaling pathways to prevent cancer, diabetes and heart diseases. Thus, A. hirtifolium and the compounds present in this plant may be promising candidate for various disease due to its wide pharmacological activities. In this review, we discussed pharmacological activities and disease prevention activities of A. hirtifolium by its modulating role of biochemical and molecular mechanisms.