Author(s):
G. Ravi, P. Subhash Chandra Bose, Valluru Ravi, Damineni Sarita, P. Srikanth Reddy, Sandeep Kanna
Email(s):
penjurisubhash@gmail.com
DOI:
10.5958/0974-360X.2020.00682.4 
Address:
G. Ravi1, P. Subhash Chandra Bose1, Valluru Ravi, Damineni Sarita2, P. Srikanth Reddy1, Sandeep Kanna1
1Department of Pharmaceutics, MNR College of Pharmacy, Sangareddy - 502294, Telangana State, India.
2Department of Pharmaceutics, Sultan-ul-Uloom College of Pharmacy, Hyderabad-500034, TS, India.
*Corresponding Author
Published In:
Volume - 13,
Issue - 8,
Year - 2020
ABSTRACT:
The aim of the present study was to develop controlled release formulation of Oxybutynin to maintain constant therapeutic levels of the drug for over 12 hrs. Karaya gum, Acacia and Tragacanth were employed as polymers. All the formulations were passed various physicochemical evaluation parameters and they were found to be within limits. From the dissolution studies it was evident that the formulation (F4) showed better and desired drug release pattern i.e., 98.14 % in 12 hours. It contains the Acacia polymer. It followed Zero order release kinetics mechanism.
Cite this article:
G. Ravi, P. Subhash Chandra Bose, Valluru Ravi, Damineni Sarita, P. Srikanth Reddy, Sandeep Kanna. Development and Evaluation of oral controlled release tablets of oxybutynin using various polymers. Research J. Pharm. and Tech. 2020; 13(8):3854-3860. doi: 10.5958/0974-360X.2020.00682.4
Cite(Electronic):
G. Ravi, P. Subhash Chandra Bose, Valluru Ravi, Damineni Sarita, P. Srikanth Reddy, Sandeep Kanna. Development and Evaluation of oral controlled release tablets of oxybutynin using various polymers. Research J. Pharm. and Tech. 2020; 13(8):3854-3860. doi: 10.5958/0974-360X.2020.00682.4 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2020-13-8-55
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