Houssam Hamdane, Rim M. Harfouch
Email ID Not Available
Houssam Hamdane1, Rim M. Harfouch2*
1Department of Laboratory Medicine, Faculty of Medicine, Tartous University, Syria.
2Department of Microbiology and Biochemistry, Faculty of Pharmacy, Al Andalus University, Qadmous, Syria.
Volume - 14,
Issue - 1,
Year - 2021
Aim of study: This study is the first done in the blood bank of Tartus to study the percentage of infected donors with hepatitis B and C. The aim was to determine the serological prevalence of Hepatitis B and C infection among Syrians, and factors that increase the risk of infection. Method of study: The subjects were blood donors at the Blood Transfusion Center in Tartus city from 02/01/2017 to 31/12/2017, all personal data of donors relating to age, gender, professional status and medical. history were recorded. After collecting blood units, a blood sample of 5 ml was taken in the EDTA tube for testing, using Enzyme -Linked Immunosorbent Assay (Biokit®, Spain), we calculated the value of CUT-OFF according to the manufacturer's instructions. at any positive result, the tube was retested in duplicate before final interpretation. The statistical comparison was conducted and the p value of <0.05 was considered statistically significant. Results: The study showed a significant decrease in the number of donors with hepatitis B and C in Tartus governorate, which makes this percentage the lowest in Syria and developing countries, and reduce state spending on patient’s treatment. Conclusion: The study emphasizes the importance of spreading the culture of blood donation because, in addition to the fact that blood donation is a humanitarian duty, tests performed free in blood banks, may alert us early to infection with these diseases, and the results are reported to the Ministry of health, which may be remedied in the premiere stages.
Cite this article:
Houssam Hamdane, Rim M. Harfouch. Hepatitis B and C among blood donors in Tartous city, Syria. A Retrospective study. Research J. Pharm. and Tech. 2021; 14(1):442-444. doi: 10.5958/0974-360X.2021.00080.9
Houssam Hamdane, Rim M. Harfouch. Hepatitis B and C among blood donors in Tartous city, Syria. A Retrospective study. Research J. Pharm. and Tech. 2021; 14(1):442-444. doi: 10.5958/0974-360X.2021.00080.9 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2021-14-1-80
1. Ansari SH, Shamsi TS, Khan MT, Perveen K, Farzana T, Erum S. Seropositivity of hepatitis C, hepatitis B and HIV in chronically transfused B-thalassaemia major patient. Jcoll Physicians Surg Pak. 2012;22 (9): 610-1
2. Al-Sheyyab M, Batieha A, El-Khateeb M. The prevalence of hepatitis B, hepatitis C and human immune deficiency virus markers in multi-transfused patients. J Trop Pediatr. 2001; 47(4):239-42
3. Zeng F, Guo P, Huang Y, et al. Epidemiology of hepatitis B virus infection: results from a community-based study of 0.15 million residents in South China. Sci Rep. 2016; 6:36186. Published 2016 Nov 7.
4. Yacoub R, Al Ali R, Moukeh G, Lahdo A, Mouhammad Y, Nasser M. Hepatitis B vaccination status and needlestick injuries among healthcare workers in syria. J Glob Infect Dis. 2010;2(1):28–34
5. H. Bashour and G. Muhjazi , Hepatitis B and C in the Syrian Arab Republic: a review. Eastern Mediterranean Health Journal, 2016. 22(4): 267-73
6. Sharifi Z, Milani S, Shooshtari MM. Study on efficacy of hepatitis B immunization in vaccinated beta thalassemia children in Tehran. Iran J Pediatr. 2010; 20(2):211-5.
7. Karim M, Laham H. Prevalence of viral hepatitis B and C in Syria. Syrian Epidemiol Bull. 2008; 3:10-11
8. Mohammadi Z., Keshtkar A., Eghtesad S., Jeddian A., Pourfatholah AA., Maghsudlu M., Zadsar M., Mahmoudi Z., Shayanrad A., Poustchi H., Malekzadeh R. Epidemiological Profile of Hepatitis B Virus Infection in Iran in the Past 25 years; A Systematic Review and Meta-analysis of General Population Studies. Middle East J Dig Dis. 2016 Jan;8(1):5-18.
9. Tavoschi L., Duffell E., de Carvalho Gomes H., Amato-Gauci A. European Centre for Disease Prevention and Control. Systematic review on hepatitis B and C prevalence in the EU/EEA. Stockholm: ECDC; 2016. Catalogue number TQ-02-16-837-EN-N. https://www.ecdc.europa.eu/sites/default/ files/media/en/publications/Publications/systematic-review-hepatitis-B-C-prevalence.pdf