Author(s):
Samir Issa Bloukh, Nageeb A. Hassan, Rand S. AlAni, Sabrina Ait Gacem
Email(s):
sabrinaaitgacem@yahoo.com
DOI:
10.5958/0974-360X.2021.00084.6
Address:
Samir Issa Bloukh1, Nageeb A. Hassan1, Rand S. AlAni1, Sabrina Ait Gacem2*
1Department of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, Ajman, UAE.
2Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Ajman University, Ajman, UAE.
*Corresponding Author
Published In:
Volume - 14,
Issue - 1,
Year - 2021
ABSTRACT:
Background: Urinary tract infection (UTI) is an infection that can take place in both genders and anywhere within the urinary tract and results from certain microorganisms such as bacteria which are the most common cause of UTI. In case it was a bacterial infection the physician usually administers antibiotics depending on the nature of the UTI and in some cases antibiotic resistance might occur. Objectives: To determine the prevalence of urinary tract infection in pregnant and non-pregnant women in UAE, distribution of bacteria which cause UTI and its sensitivity and resistance to antibiotics. Methods: A Cross-sectional study was carried out. A total of 300 women results were retrospectively analyzed in the study. Results: From those 300 study participants (39%) were pregnant and (61%) non-pregnant. The percentage of resistance in the uropathogens in pregnant patients was more (69.49%) compared to those in non-pregnant patients (56.59 %). The pathogens distribution shows that the most common pathogen is Escherichia Coli (58%). This study shows that E. coli has high resistance to Amoxicillin. Conclusion: Pregnant women are more susceptible to UTI in comparison to non-pregnant women and the main cause of UTI is the E.coli bacteria. The highest uropathogen resistance was against amoxicillin, while the antibiotic of choice for UTI treatment is ciprofloxacin due to its high sensitivity. UTI needs to be detected and treated promptly since treatment has shown its efficiency in preventing pregnancy related complications.
Cite this article:
Samir Issa Bloukh, Nageeb A. Hassan, Rand S. AlAni, Sabrina Ait Gacem. Urinary Tract Infection and Antibiotic Resistance among Pregnant and Non-pregnant females in UAE. Research J. Pharm. and Tech. 2021; 14(1):461-465. doi: 10.5958/0974-360X.2021.00084.6
Cite(Electronic):
Samir Issa Bloukh, Nageeb A. Hassan, Rand S. AlAni, Sabrina Ait Gacem. Urinary Tract Infection and Antibiotic Resistance among Pregnant and Non-pregnant females in UAE. Research J. Pharm. and Tech. 2021; 14(1):461-465. doi: 10.5958/0974-360X.2021.00084.6 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2021-14-1-84
REFERENCES:
1. Dielubanza EJ, Schaeffer AJ. Urinary tract infections in Women. Med Clin North Am. 2011; 95: 27-41.
2. Salvatore S, Salvatore S, Cattoni E, Siesto G, Serati M, Sorice P, et al. Urinary tract infections in women. European Journal of Obstetrics & Gynecology and Reproductive Biology. 2011; 156:131-6.
3. Haider G, Zehra N, Munir AA, Haider A. Risk factors of urinary tract infection in pregnancy. The Journal of the Pakistan Medical Association. 2010; 60:213.
4. Ovalle A, Levancini M. Urinary tract infections in pregnancy. Current opinion in urology. Current Opinion in Urology. 2001; 11:55-9.
5. Sandberg T, Kaijser B, Lidin-Janson G, Lincoln K, Orskov F, Orskov I, et al. Virulence of Escherichia coli in relation to host factors in women with symptomatic urinary tract infection. Journal of Clinical Microbiology. 1988; 26:1471-6.
6. Solomon YM. Bacterial Uropathogens and Their Antibiotic Susceptibility Pattern at Dessie Regional Health Laboratory. Pyrex Journal of Microbiology and Biotechnology Research. 2017; 3:1-9.
7. Getenet B, Wondewosen T. Bacterial uropathogens in urinary tract infection and antibiotic susceptibility pattern in Jimma University specialized Hospital. Ethiopia. Ethiop J Health Sci. 2011; 21(2): 141-146.
8. Sujatha R, Manju N. Prevalence of Asymptomatic Bacteriuria and its Antibacterial Susceptibility Pattern among Pregnant Women Attending the Antenatal Clinic at Kanpur, India. J Clin Diagn Res. 2014; 8(4):1–3.
9. Watkins R, Van DD. Current trends in the treatment of pneumonia due to multidrug-resistant Gram-negative bacteria. F1000 Research. 2019; 8:121.
10. Bischoff S, Walter T, Gerigk M, Ebert M, Vogelmann R. Empiric antibiotic therapy in urinary tract infection in patients with risk factors for antibiotic resistance in a German emergency department. BMC Infectious Diseases. 2018; 18:3-7.