S. Navaith Ahmed, P. Kalaivani, P. Amudha, B. Usharani
S. Navaith Ahmed, P. Kalaivani, P. Amudha, B. Usharani*
Department of Biochemistry, Vels Institute of Science, Technology and Advanced Studies, Pallavaram, Chennai, Tamilnadu-600117, India.
Volume - 14,
Issue - 12,
Year - 2021
Sea grass are good source of potent drug which has medicinal properties and able to cure human disease. One such marine plant is the Enhalus acoroides which belong to hydrocharitaeceae family. This marine species are widely distributed in the tropics of Indian and western Pacific Ocean and the species were collected from Ramanathapuram district for further process. This study reveals about the bioactive components present in Enhalus acoroides and identified its biological activity by Gas chromatography Mass spectrometry analysis using hydroalcoholic extract. The compounds present in Enhalus acoroides are Benzoic acid, 2- methyl 7- oxa bicyclol heptanes, 1, 3 Nonadiene, silane, ethoxytriethyl. Biological activities of the compounds present in the sample include antioxidant, hypocholesterolemic, antihypertensive, anti-inflammatory, anti-microbial, antiviral and anti-hepatotoxic effect.
Cite this article:
S. Navaith Ahmed, P. Kalaivani, P. Amudha, B. Usharani. Identification of Bioactive Phytocomponents of Hydroalcoholic Extract of Enhalus acoroides by Gas Chromatography- Mass Spectrometry Analysis. Research Journal of Pharmacy and Technology. 2021; 14(12):6511-5. doi: 10.52711/0974-360X.2021.01126
S. Navaith Ahmed, P. Kalaivani, P. Amudha, B. Usharani. Identification of Bioactive Phytocomponents of Hydroalcoholic Extract of Enhalus acoroides by Gas Chromatography- Mass Spectrometry Analysis. Research Journal of Pharmacy and Technology. 2021; 14(12):6511-5. doi: 10.52711/0974-360X.2021.01126 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2021-14-12-56
1. Jadhav Sameer S, Salunkhe Vijay R and Magdum Chandrakant S. Daily Consumption of Antioxidants: -Prevention of Disease is better than Cure. Asian J. Pharm. Res. 2013; 3(1): 33-39.
2. Vignesh Balaji E, Tamil Selvan A, Srinivasan A and Nandhini S. Punica granatum root (s): Phytocompounds analysis, Anti-oxidant and Anti-microbial activity. Asian J. Pharm. Ana. 2019; 9(3): 123-127.
3. Tapsell LC, Hemphill I, Cobiac L, Sullivan DR, Fenech M and Patch CS. Health benefits of herbs and species: The past, the present, the future. Medical Journal of Australia. 2008; 185(4): S1-S24.
4. Vanitha Varadharajan, Umadevi Kumba Janarthanan and Vijayalakshmi Krishnamoorthy. Physicochemical, Phytochemical screening and profiling of Secondary metabolites of Annona squamosa leaf extract. World Journal of Pharmaceutical Research. 2012;1(4): 1143-1164.
5. Kale PM. A Review Article on Euphorbia hirta uses and pharmacological activities. Asian J. Res. Pharm. Sci. 2016; 6(3): 141-145.
6. Anand, Vijay, Bharathi and Vadivelu. Chemical Characterization from GC-MS studies of ethanolic extract of Macrotyloma uniflorum. Research Journal of Pharmacy and Technology. 2016; 9(3).
7. Hussein J, Hussein & Hameed, Imad & Hadi and Mohammed. Using Gas Chromatography-Mass Spectrometry (GC-MS) technique for analysis of Bioactive Compounds of methanolic leaves extract of Lepidium sativum. Research Journal of Pharmacy and Technology. 2017;10(11).
8. Suganya S, Bharathidasan R, Senthilkumar G, Madhanraj P and Panneerselvam A. Antibacterial activity of essential oil extracted from Coriandrum sativam (L.) and GC-MS analysis. Research J. Science and Tech. 2012; 4(5): 203-207.
9. Preeti Tiwari and Rakesh K Patel. Estimation of Total Phenolics and Flavonoids and Antioxidant potential of Ashwagandharishta prepared by traditional and modern methods. Asian J. Pharm. Ana. 2013; 3(4): 147-152.
10. Abdhul Basheer Chandini, Govindasamy Balasubramani, Raendran Ramkumar, Rajamani Sowmiya, Manickam Dhakshinamoorthi Balamurugan, Pudhupalayam Thangavelu Kalaichelvan and Pacaiappan Perumal. Structural Characterization antioxidant and invitro cytotoxic properities of seagrass, Cymodoceae serrulata (R.Br.) Asch. & Magnus mediated silver nanoparticles. Journal of Photochemistry and Photobiology B: Biology. 2015; 153:145-152.
11. Ragupathy Raja Kanan Rengasamy, Arumugam Radjassegarin and Anantharaman Perumal. Seagrass as potential source of medicinal food ingredients: Nutritional analysis and multivariate approach. Biomedicine and Preventive Nutrition. 2013; 3(4): 375-380.
12. Sakyaroj J, Preedanon S, Suphaphon O, Jones EBG and Phongpaichit S. Phylogenetic diversity of endophyte assemblages associated with the trophical seagrass Enhalus acoroides in Thailand. Fungal Diverity. 2010; 42: 27-45.
13. Rengasamy Ragupathi Raja Kannan, Radassegarin Arumugam aned Perumal Anantharaman. Chemical Composition and antibacterial activity of Indian seagrass against urinary tract pathogens. Food Chemistry. 2012; 135(4): 2470- 2473.
14. Fernando Boisset, Pablo P and Ferror Galligo. Typification of Indo-Pacific seagrass Enhalus acoroides (Hydrocharitaceae). The Journal of International Association for Plant Taxonomy. 2016; 65(3): 602-604.
15. Amudha P, Vanitha V, Mohanasundaram S, Pushpabharathi V and Jayalakshmi M. Phytochemical Analysis and invitro antioxidant screening of seagrass - Enhalus acoroides. 2017; 8(2): 256-263.
16. Suja Pandian R and Thajun Noora A. GC-MS analysis of phytochemical compounds present in the leaves of Citrus medica L. Research J. Pharm. And Tech. 2019; 12(4): 1823-1826.
17. Srinivasan K, Sivasubramanian S and Kumaravel S. Phytochemical profiling and GC-MS study of Adhatoda vasica leaves. Int.J.Pharm.Bio.Sci. 2013; 5(1): 714-720.
18. Vijayalingam TA and Rajesh NV. Seagrass has potential source of fodder for livestock: Complete proximate and gas chromatography- mass spectrometry (GCMS) analysis. Annals of Phytomedicine: An International Journal. 2019; 8(2): 93-98.
19. Isao Kubo, Hisae Muroi and Aya Kubo. Structural function of antimicrobial long-chain alcohols and phenols. Bioorganic and Medical Chemistry. 1995; 3(7): 873-880.
20. Vasudevan Aparna, Kalarickal V Dileep, Pradeep K Mandal, Ponnuraj karthe, Chittalakottu Sadasivan and Madathilkovilakadu Haridas. Anti- inflammatory property of n- Hexadeconic acid: Structural evidence and Kinetic assessment. Chemical Biology and Drug Design. 2012; 80: 434-439.
21. Sujatha S, Anand S, Sangeetha KN, Shilpa K, Lakshmi J, Balakrishnan A and Lakshmi BS. Biological evaluation of (3β)-Stigmast-5-en-3-ol as potent antidiabetic agent in regulating glucose transport using invitro model. International journal of Diabetes Mellitus. 2010; 2(2): 101-109.
22. Dr.Duke. Phytochemical and Ethno botanical Databases, Phytochemical and Ethnobotanical Databases. 2013.
23. Adedoyin BJ, Okeniyi SO, Garba S and Salihu L. Cytotoxicity, antioxidant and antimicrobial activities of essential oil extracted from Euphorbia heterophylla plant. Top class Journal of Herbal Medicine. 2013; 2(5): 84-89.
24. Sermakkani M and Thangapandiyan V. GC-MS Analysis of Cassia italica leaf methanol extract. Asian Journal of Pharmaceutical and Clinical Research. 2012; 5(2): 90-94.
25. Suman T, Chakkaravarthi K and Elangomathavan R. Phyto-chemical profiling of Cleistanthus collinus leaf extracts using GC-MS analysis. Research J. Pharm. and Tech. 2013;6(11): 1173-1177.
26. Chanchal Kumari and Deepalakshmi J. Qualitative and GC-MS analysis of phytoconstituents of Parthenium hysterophorus Linn. Res. J. Pharmacognosy and Phytochem. 2017;9(2): 105-110.
27. Chandramohan A and Divya SR. Comparison of Antioxidant Activity in Gracilaria edulis and Hypnea valentiae. International Journal of Advance Research, Ideas and Innovations in Technology. 2017; 3: 294-296.
28. Arulraj J, Shanmugaiah V and Lakshmanan N. Studies on Phytochemical analysis and antimicrobial activity of Tulsi (Ocimum sanctum Linn) leaf extract against human and fish pathogens. International journal of Advanced Life sciences. 2014; 7(2): 27-34.