Author(s):
Neeraj Pant, Samuel Gideon George P, Dipendra Bhatt, Ramesh Datta Pant, Kasthuri Pandiyan
Email(s):
psgsamuel@gmail.com
DOI:
10.5958/0974-360X.2021.00184.0 
Address:
Neeraj Pant1, Samuel Gideon George P1*, Dipendra Bhatt1, Ramesh Datta Pant1, Kasthuri Pandiyan2
1Department of Pharmacy Practice, Krupanidhi College of Pharmacy, Bangalore, 560035.
2Department of Psychiatry, MVJ Medical College and Research Hospital, Bangalore, 562114.
*Corresponding Author
Published In:
Volume - 14,
Issue - 2,
Year - 2021
ABSTRACT:
Objectives: To study the prescription pattern of psychotropic drugs in different psychiatric disorder. Methodology: The prospective observational study was conducted in 100 psychiatric in-patients at a tertiary care hospital in Bangalore. Study was conducted on gaining approval from the institutional human ethical committee. All patients who meet the study criteria were enrolled in to the study after taking the informed consent from the patients or their legal representatives. The demographic, clinical and medications data were documented into a specially designed case report form. All the data was analyzed using descriptive statistics. Results and Discussion: In 100 study subjects 194 different psychotropic drugs were prescribed. Among 194 psychotropic drugs 38.14% were sedatives and hypnotics, 36.08% were antipsychotics, 18.55% were antidepressants and 7.21% were mood stabilizer. Conclusion: This study found that schizophrenia was the most common illness in psychiatric patients. Male patients were more prone to psychiatric disorders than female. Most of the study populations were non-alcoholic and non-smokers. Sedatives and hypnotics of benzodiazepine class were found to be the most commonly used drugs followed by antipsychotics, anti-depressants and mood stabilizers in the studied population. Future studies to evaluate the drug utilization evaluation of psychotropic drugs in large patient populations are much needed to promote patient safety and increase the quality of psychiatric patients.
Cite this article:
Neeraj Pant, Samuel Gideon George P, Dipendra Bhatt, Ramesh Datta Pant, Kasthuri Pandiyan. Drug Utilization Evaluation of Psychotropic Drugs in the Psychiatry in-patient Department of Tertiary Care Hospital. Research J. Pharm. and Tech. 2021; 14(2):1033-1036. doi: 10.5958/0974-360X.2021.00184.0
Cite(Electronic):
Neeraj Pant, Samuel Gideon George P, Dipendra Bhatt, Ramesh Datta Pant, Kasthuri Pandiyan. Drug Utilization Evaluation of Psychotropic Drugs in the Psychiatry in-patient Department of Tertiary Care Hospital. Research J. Pharm. and Tech. 2021; 14(2):1033-1036. doi: 10.5958/0974-360X.2021.00184.0 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2021-14-2-80
REFERENCES:
1. American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 3rd ed. Washington: American Psychiatric Association; 1980.
2. American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC.
3. World Health Organization. Strengthening Mental Health Promotion. The World health report 2001 - Mental Health (Fact sheet no.220): New Understanding, New Hope., Geneva
4. Math SB, Chandrashekar CR, Bhugra D. Psychiatric epidemiology in India. The Indian journal of Medical research 2007 Sep; 126(3): 183–92.
5. Murthy R. Mental Health Programme in the 11th five-year plan. The Indian Journal of Medical Research. 2007 Jun; 11: 707–12.
6. Collins, Pamela Y; Patel, Vikram; Joestl, Sarah S et al. Scientific Advisory Board the Executive Committee. "Grand challenges in global mental health". Nature 475(7354): 27–30.
7. Mojtabai R, Olfson M (2010) National trends in psychotropic medication polypharmacy in office-based psychiatry. Arch Gen Psychiatry 67: 26-36.
8. Zohar J, Stahl S, Moller HJ, Blier P, Kupfer D, et al. (2015) A review of the current nomenclature for psychotropic agents and an introduction to the Neuroscience based Nomenclature. Eur Neuropsychopharmacol 25: 2318-2325.
9. Gross F. Drug utilization Theory and practice the present situation in the Federal Republic of Germany. Eur J Clin Pharmcol 1981, 19(6):387-94.
10. WHO. Action programme for essential drugs: how to investigate drug use in health facilities. Geneva: World Health Organization 1993.
11. Davidson JR, Feltner DE, Dugar A. Management of generalized anxiety disorder in primary care: identifying the challenges and unmet needs. Prim Care Companion J Clin Psychiatry 2010, 12(2): PCC.09r00772.
12. Nakao M, Takeuchi T, Yano E. Prescription of benzodiazepines and antidepressants to outpatients attending a Japanese university hospital. Int J Clin Pharmacol Ther 2007, 45(1):30-5.
13. Roopadevi HS, Ramesh KN, Nagabushan H. Pattern of psychotropic prescription in a tertiary care teaching hospital: a critical analysis. Asian J Pharm Clin Res. 2015;8(5):252-5.
14. Goyal V, Munjal S, Gupta R. Drug utilization pattern of psychotropic drugs prescribed in the psychiatric department of a tertiary care government hospital, Rajasthan. Journal of Dental and Medical Sciences. 2016;15(7):80-7.
15. Chaturvedi R, Sharma P. Drug utilization study of psychotropic drugs prescribed in psychiatry OPD of LN Medical College associated JK Hospital, Bhopal District, Madhya Pradesh. Depression. 2016; 218:36-3.
16. Olajide A, Mansfield M, Olubankole O, Udoka O. Psychotropic drug prescription practice in psychiatric in-patients in Saskatchewan, Canada. J Neuropsychopharmacol Mental Health. 2016;1(114):2.