ABSTRACT:
Oral routes are mainly preferred route to administer and to deliver drug. Most common oral dosage forms are capsule and tablet. In some cases, the solid oral dosage form may become difficult in swallowing e.g. sudden episode of allergic reaction, motion sickness, coughing, unavailability of water, fear of choking and in different age group of patient and patients who suffer from dysphagia. The administration of pediatric and geriatric population is the advantages of oral film technology where the difficulty in swallowing and larger oral dosage forms is eliminated. It is an interchange platform for molecules that undergo first pass metabolism. To overcome these problems, drug delivery systems of fast dissolving has been developed. Fast dissolving oral delivery systems are solid dosage forms, which dissolve or disintegrate within 1 min when placed in the mouth without chewing or water. The drug are formulated by Oral dissolving films incorporating with selected oral cavity absorption enhancers oral dissolving film carriers are specially designed. Oral films are formulated by using polymers, plasticizers, saliva stimulating agents, colours, flavors and sweeteners. Different methods are reported in literature as solvent casting method, hot melt extrusion method, rolling method and solid dispersion method for the preparation of film. The objective is to target local, for rapid onset of action, to avoid first pass metabolism and to mask bitter taste of drugs. Overall it leads to patient compliance with improved therapeutic success.