Author(s):
Sharmila D, Poovarasan A, Pradeep E, Mudiganti Ram Krishna Rao, Prabhu K
Email(s):
mrkrao1455@gmail.com
DOI:
10.5958/0974-360X.2021.00250.X 
Address:
Sharmila D1, Poovarasan A2, Pradeep E2, Mudiganti Ram Krishna Rao3*, Prabhu K4
1Assit. Professor, Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai.
2 Student, Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai.
3 Professor, Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai.
4Associate Professor, Department of Anatomy, Sree Balaji Medical College and Hospital, Chrompet, Chennai.
*Corresponding Author
Published In:
Volume - 14,
Issue - 3,
Year - 2021
ABSTRACT:
The present study deals with the GC MS analysis of one Ayurvedic medicine, Nasika Churna which is used for the treatment of respiratory diseases. Nasika churnam was procured from a standard Ayurvedic vendor at Chennai and subjected to GC MS analysis following standard protocol. Some important molecules such as Cyclobutane-1,1-dicarboxamide, N,N'-di-benzoyloxy-, Ar-tumerone, Ethyl p-methoxycinnamate, Tetradecanoic acid, cis-13-Octadecenoic acid, cis-Vaccenic acid, Dodecanoic acid, 2-phenylethyl ester, Stigmasterol, .gamma. Sitosterol, Succinic acid, di(3,7-dimethyloct-6-en-1-yl) ester etc. indicate the medicinal roles which are similar to the medicinal roles attributed to Nasika churna in Ayurveda. Further probing into the activities of each molecule is warranted.
Cite this article:
Sharmila D, Poovarasan A, Pradeep E, Mudiganti Ram Krishna Rao, Prabhu K. GC MS analysis of one Ayurvedic formulation “Nasika churnam”. Research J. Pharm. and Tech 2021; 14(3):1400-1404. doi: 10.5958/0974-360X.2021.00250.X
Cite(Electronic):
Sharmila D, Poovarasan A, Pradeep E, Mudiganti Ram Krishna Rao, Prabhu K. GC MS analysis of one Ayurvedic formulation “Nasika churnam”. Research J. Pharm. and Tech 2021; 14(3):1400-1404. doi: 10.5958/0974-360X.2021.00250.X Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2021-14-3-38
REFERENCES:
1. Shil S, Rao MRK, Prabhu K, Amuthvalli K. Thin layer chromatography - as a tool for standardization of Ayurvedic medicine, Trikatu churna. Indo American J of Pharmaceutical Sciences. 2018; 5(6): 5039-5046.
2. Kotteswari M, Rao MRK, Siva Kumar, Prabhu K, Lakshmi Sundaram R, Shruthi Dinakar.. GC MS analysis of one Ayurvedic preparation Aswagandharishtam. Biomedical and Pharmacology Journal, 2018; 11(2):1061-1072.
3. Edel Queen Z, Rao MRK, Jacintha Anthony, Prabhu K, Kavimani M, Shanthi Balasubramanian B, Lakshmi Sundaram R, Shruthi Dinakar. Antioxidant study of one Ayurvedic preparation Amrithamehari churnam. IJPT, 2018; 10(2): 31312-31318
4. Kotteswari M, Rao MRK, Prabhu K, Siva Kumar, Shil S. Antioxidant studies of one Ayurvedic medicine Aswagandharishtam. Asian J of Pharmaceutical and Clinical Res, 2018; 11(11): 227-231.
5. Praveen Kumar P, Rao MRK, Arul Amutha Elizabeth, Prabhu K, Lakshmi Sundaram R, Shruthi Dinakar. “The GC MS Analysis of One Ayurvedic Medicine Sahacharadi Kashayam. Int J of Pharmacy and Technology, 2018; 10(1): 31214-31230
6. Hassan Mohammad, Prabhu K, Rao MRK, Lakshmi Sundaram R, Shil S, Vijayalakshmi N. The GC MS studies of one Ayurvedic medicine, Amritarishtam. Research J. Pharm. and Tech, 2019; 12(1):351-356
7. Muttevi Hyagreva Kumar, Prabhu K, Rao MRK, Lakshmi Sundaram R, Shil S, Arun Kumar S. The GC MS study of one Ayurvedic medicine, Vasakadyaristam. Research J of Pharmacy and Technology, 2019; 12(2): 569-573
8. Hassan Mohammad, Prabhu K, Rao MRK, Lakshmi Sundaram R, Shil S, Vijayalakshmi N. The GC MS study of one Ayurvedic medicine, Khadirarishtam. Research J of Pharmacy and Technology, 2019; 12(2): 535-540
9. Hassan Mohammad, Prabhu K, Rao MRK, Lakshmi Sundaram R, Shil S, Vijayalakshmi N, Sruthi Dinakar. The GC MS study of one Ayurvedic medicine, Arghwadarishtam. Research J of Pharmacy and Technology. 2019; 12(3):1111-1114
10. Hassan Mohammad, Prabhu K, Rao MRK, Lakshmi Sundram R, Sruthi Dinakar, Sathish Kumar M, Vijayalakshmi N. The GC MS study of one Ayurvedic Pain relieving OIL “Karpooradi thailam”. Drug Invention Today, 2019; 12(7):1542-1546
11. Hassan Mohammad, Prabhu K, Rao MRK, Lakshmi Sundram R, Sruthi Dinakar, Sathish Kumar M, Vijayalakshmi N. The GC MS study of one Ayurvedic Pain relieving OIL “Mahamasha thailam”. Drug Invention Today, 2019; 12(7): 1524-1527.
12. Yuvaraj R, Rao MRK, Prabhu K, Lakshmi Sundram R, Shil S, Sathish Kumar M, Vijayalakshmi N. The GC MS study of one medicinal plant, Stachyterpheta indica. Drug Invention Today, 2019; 12(9):1665-1669
13. Muttevi Hyagreva Kumar, Prabhu K, Rao MRK, Lakshmi Sundram R, Shil S, Sathish Kumar M, Vijayalakshmi N. The GC MS study of one medicinal plant, Dodonea angutifolia . Drug Invention Today, 2019; 12(9):1661-1664
14. Rao MRK, Anisha G, Prabhu K, Shil S, Vijayalakshmi N. Preliminary phytochemical and GC MS study of one medicinal plant Carissa carandas. Drug Invention Today, 2019; 12(9):1629-1634
15. Vijayalakshmi N, Mudiganti Ram Krishna Rao. The antioxidant studies of two medicinal plants, Sphaeranthus indicus and Psophocarpus tetragonolobus. Asian J of pharmaceutical and Clinical Res, 2019; 12(1): 321-327.
16. Balakrishnan G, Sampad Shil, Vijalakashmi N, Mudiganti Ram Krishna Rao. Green synthesis of Copper (cu) nanocrystallites using Triphala churnam and their anti-microbial studies. Drug Invention Today, 2019; 12(9):2038-2044
17. Sivakumaran G, Prabhu K, Mudiganti Ram Krishna Rao, Sumathi Jones, Lakshmi Sundaram R, Rahul Ulhas V, Shruthi Dinakar, Vijayalakshmi N. Gas chromatography–mass spectrometry analysis of one ayurvedic oil, Anu thailam. DIT, 2019; 11(10):2675-2678.
18. Muttevi Hyagreva Kumar, Prabhu K, Mudiganti Ram Krishna Rao, Shanthi B, Kavimani N, Shruti Dinakar, Lakshmi Sundaram R, Vijayalakshmi N, Sampad Shil. Gas chromatography mass spectrometry analysis of one Ayurvedic skin oil, Eladi Kera Thailam. DIT, 2019; 11(10):2657-2660
19. Sivakumaran G, Prabhu K, Mudiganti Ram Krishna Rao, Sumathi Jones, Lakshmi Sundaram R, Rahul Ulhas V, Shruthi Dinakar, Vijayalakshmi N. Gas chromatography–mass spectrometry analysis of one ayurvedic oil, Ksheerabala Thailam, DIT, 2019; 11(10):2661-2665
20. Narayanan G, Prabhu J, Mudiganti Ram Krishna Rao, Kamala Kannan, Lakshmi Sundaram R, Shruthi Dinakar, N. Vijayalakshmi. Gas chromatography–mass spectrometry analysis of one ayurvedic medicine, Kutajarishtam. DIT, 2019; 11(10): 2666-2669
21. Narayanan G, Prabhu K, Rao MRK, Sumathi Jones, Lakshmi Sundaram R, Rahul Ulhas V, Vijayalakshmi N. Gas chromatography–mass spectrometry analysis of one Ayurvedic antiobesity medicine, Lohasava. 2019; 11(10):2670-2674
22. Rao MRK, Vijayalakshmi N, Prabhu K, Sathish Kumar M. The gas chromatography–mass spectrometry study of Moringa oleifera seeds. DIT, 2109; 12(10):2172-2175
23. Sivakumaran K, Prabhu K, Rao MRK, Sumathi Jones, Lakshmi Sundaram R, Rahul Ulhas V, Vijayalakshmi N. Gas chromatography–mass spectrometry analysis of one Ayurvedic oil, Triphaladi Thailam. DIT, 2109; 11(10):2679-2683
24. Narayanan G, Prabhu K, Mudiganti Ram Krishna Rao, Kamala Kannan, Lakshmi Sundaram R, Shruthi Dinakar, Vijayalakshmi N. Gas chromatography–mass spectrometry analysis of one Ayurvedic medicine, Drakshadi Kashayam. DIT, 2019; 11(10):2652-2656.
25. Muttevi Hyagreva Kumar, Prabhu K, Mudiganti Ram Krishna Rao, Lakshmi Sundram R, Sampad Shil, Sathish Kumar M, Vijayalakshmi N. The GC MS study of one medicinal plant, Aristolochia Indica. DIT, 2020; 12(12): 2919-2923.
26. Nitin V. Kokare, Kiran A. Wadkar, Manish S. Kondawar. Review on standardization of Herbal churna. Int. J. Res. Ayurveda Pharm. 2014; 5(3):397-401
27. Panda P, Dighe D, Das SK, Rao MM. A review of pharmaceutical and therapeutical uses of churnas (Powder) in Ayurveda. Int Ayurvedic Medical J, 2017, 5(11), 4233-4246.
28. Baskaran G, Salvamani S, Ahmed SA, Shaharuddin NA, Pattiram PD. HMG-CoA reductase inhibitory activity and phytocomponent investigation of Basella alba leaves extract as a treatment for hypercholesterolemia. Drug Des Dev Ther, 2015; 2015:509-517.
29. Hein DW, McQueen CA, Grant DM, Goodfellow GH, Kalubar FF, Weber WW. Pharmacogenetics of the arylamine N-Acetyltransferases: a symposium in honour of Wendell W. Webe. Drug Metabo Dispos, 2000; 28:1425-1432.
30. Sim E, Fakis G, Laurieri N, Boukouvala S. 2012. Arylamine N-Transfereases- from drug metabolism and pharmacogenetics to identification of novel targets for pharmacological intervention. Adv Pharmacol, 2012; 63, 169-205
31. Scheinfeld N. "A comprehensive review and evaluation of the side effects of the tumor necrosis factor blockers etanercept, infliximab and adalimumab". J Dermatolog Treat. 2003;m15 (5): 280–94.
32. Martinez A, Gil C. c-AMP-specific phosphodiesterase inhibitors: promising drugs for inflammatory and neurological diseases. Epert Opin Ther Pat, 2014; 24(12): 1311-1321.