Author(s):
Laith S Abdulhaleem, Omar F Abdul-Rasheed, Salwa J Abdullah Al-Awadi, Thuraya H Abdullah
Email(s):
Laith.shukri_as@yahoo.com
DOI:
10.52711/0974-360X.2021.00360 
Address:
Laith S Abdulhaleem1*, Omar F Abdul-Rasheed2, Salwa J Abdullah Al-Awadi3, Thuraya H Abdullah4
1PhD Student, Department of Chemistry and Biochemistry, College of Medicine, Al-Nahrain University, Baghdad, Iraq.
2Department of Chemistry and Biochemistry, College of Medicine, Al-Nahrain University, Baghdad, Iraq.
3Department of Biomedical Technologies, College of Applied Biotechnology, Al-Nahrain University, Baghdad-Iraq.
4Al Imamain Teaching Hospital, Baghdad-Iraq.
*Corresponding Author
Published In:
Volume - 14,
Issue - 4,
Year - 2021
ABSTRACT:
Objectives: to assess the possible association between Angiopoietin-2 (ANGT-2) and the risk of recurrent implantation failure and to determine the possible role of it in the successfulness of in vitro fertilization process. Methods: A case control study was done on 80 female patients with Recurrent Implantation Failure (RIF) and 23 female patients with successful in-vitro fertilization (IVF) who were recruited from the Department of Obstetrics and Gynecology at Al Imamain Al-Kadhimain Medical City, Baghdad, Iraq between January and September 2019. The levels of ANGT-2 were measured in the serum of women with RIF and successful IVF and compared with those with a positive IVF and control group that comprise 74 age, BMI and sex-matched apparently healthy females. Results: The data revealed that there was a significant (p=0.007) decrease in ANGPT2 levels (2914.66±834.08) in women with recurrent implantation failure (RIF) in a comparison with controls (3235.83 ±444.16) whereas non-significant (p>0.05) differences were obtained between women with a successful in vitro fertilization (+ve IVF) and controls and also with RIF group. Conclusions: the possible association between ANGT-2 and the risk of RIF and the possibility of using it as a marker for a prognosis in women subjected to IVF process
Cite this article:
Laith S Abdulhaleem, Omar F Abdul-Rasheed, Salwa J Abdullah Al-Awadi, Thuraya H Abdullah. The association between Angiopoietin-2 and the risk of recurrent implantation failure. Research Journal of Pharmacy and Technology. 2021; 14(4):2031-4. doi: 10.52711/0974-360X.2021.00360
Cite(Electronic):
Laith S Abdulhaleem, Omar F Abdul-Rasheed, Salwa J Abdullah Al-Awadi, Thuraya H Abdullah. The association between Angiopoietin-2 and the risk of recurrent implantation failure. Research Journal of Pharmacy and Technology. 2021; 14(4):2031-4. doi: 10.52711/0974-360X.2021.00360 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2021-14-4-36
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