Author(s):
Pamula Reddy Bhavanam, Shaik Abdul Rahaman, M Mohan Varma
Email(s):
pamula1114@gmail.com
DOI:
10.52711/0974-360X.2021.00488 
Address:
Pamula Reddy Bhavanam1*, Shaik Abdul Rahaman1, M Mohan Varma2
1Department of Pharmaceutical Technology, Nirmala College of Pharmacy, Atmakuru,
Andhra Pradesh - 522503, India.
2Department of Pharmaceutical Technology, Shri Vishnu College of Pharmacy, Bhimavaram,
Andhra Pradesh - 534202, India.
*Corresponding Author
Published In:
Volume - 14,
Issue - 5,
Year - 2021
ABSTRACT:
Tamarind seed polysaccharide (TSP) micro sized mouth dissolving films were prepared to release the Amlodipine besylate drug for hypertension. TSP mouth dissolving films were prepared by solvent evaporation method which was further examined under in vitro studies. In vitro antimicrobial activities for all the mouth dissolving films were conducted by diffusion method. Form the in vitro release profile, the AML-TSP was completely showed rapid release of drug up to 98.1% than the thin films of other formulations respectively in the period of time of 10 min. The prepared AML-TSP mouth dissolving films were evaluated for drug content, weight variation, thickness, pH, folding endurance, In vitro drug release and stability studies. AML8 showed the highest drug release at the 10 min time point. The AML8 mouth dissolving film with higher amount of superdisintegrant CCS and SSG showed fastest onset of drug release.
Cite this article:
Pamula Reddy Bhavanam, Shaik Abdul Rahaman, M Mohan Varma. Tamarind Seed Polysaccharide Mouth Dissolving films for rapid drug Release in the treatment of Hypertension: In vitro Evaluation. Research Journal of Pharmacy and Technology. 2021; 14(5):2771-3. doi: 10.52711/0974-360X.2021.00488
Cite(Electronic):
Pamula Reddy Bhavanam, Shaik Abdul Rahaman, M Mohan Varma. Tamarind Seed Polysaccharide Mouth Dissolving films for rapid drug Release in the treatment of Hypertension: In vitro Evaluation. Research Journal of Pharmacy and Technology. 2021; 14(5):2771-3. doi: 10.52711/0974-360X.2021.00488 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2021-14-5-72
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