Chandanpreet Singh Sidhu, Saurabh Singh, Dileep Singh Baghel, Sachin Kumar Singh, Bimlesh Kumar, Monica Gulati, Narendra Kumar Pandey, Sheetu Wadhwa, Iqbaljeet Kaur, Hetal Aghera
email@example.com , firstname.lastname@example.org
Chandanpreet Singh Sidhu1, Saurabh Singh1*, Dileep Singh Baghel1, Sachin Kumar Singh1, Bimlesh Kumar1, Monica Gulati1, Narendra Kumar Pandey1, Sheetu Wadhwa1, Iqbaljeet Kaur1, Hetal Aghera2
1School of Pharmaceutical Sciences, Lovely Professional University, Jalandhar, Punjab, India.
2Endeavour College of Natural Health, Adelaide, Australia.
Volume - 14,
Issue - 6,
Year - 2021
Ativishadi churna is a traditional classical formulation pioneered by the science of Ayurveda. The very first reference regarding the formulation was documented in the Charka Samhita under title Ativishadi Yoga. The main indication of this formulation is to cure diarrhoea due to pitta dosha vitiation. It contains an equal part of powdered and dried Ativisha roots, Kutaj bark and Indrayava (dried Kutaj seeds). The polyherbal formulations comprise a wide range of bioactive compounds and the standardization of such formulations is a great concern these days. Hence, the present study evolves around standardizing Ativishadi Churna, for this purpose physicochemical parameters were performed of individual drugs by keeping the values of API as a standard. A complete pharmacognostic profile of ingredients has been validated to authenticate plant materials and to confirm the absence of any adulterants or impurities in the formulation. The preliminary phytochemical tests, Pharmacognostic and phytochemical standardization of the formulation were performed as a part of an SOP development. The formulation besides has been proven to possess antimicrobial properties against pathogens responsible for common infectious diseases in humans. The recent concern lies in the fact that some traditional medicines have been claimed to possess heavy metals. For this purpose, the heavy metal content has also been determined which shows that the formulation is devoid of heavy metals that may cause toxicity. The pharmacognostic and phytochemical study of this formulation would be very important for establishing standards in the future.
Cite this article:
Chandanpreet Singh Sidhu, Saurabh Singh, Dileep Singh Baghel, Sachin Kumar Singh, Bimlesh Kumar, Monica Gulati, Narendra Kumar Pandey, Sheetu Wadhwa, Iqbaljeet Kaur, Hetal Aghera. Pharmacognostical and Physico-chemical Evaluation of Ativishadi Churna – An Ayurvedic Formulation. Research Journal of Pharmacy and Technology. 2021; 14(6):3015-4. doi: 10.52711/0974-360X.2021.00528
Chandanpreet Singh Sidhu, Saurabh Singh, Dileep Singh Baghel, Sachin Kumar Singh, Bimlesh Kumar, Monica Gulati, Narendra Kumar Pandey, Sheetu Wadhwa, Iqbaljeet Kaur, Hetal Aghera. Pharmacognostical and Physico-chemical Evaluation of Ativishadi Churna – An Ayurvedic Formulation. Research Journal of Pharmacy and Technology. 2021; 14(6):3015-4. doi: 10.52711/0974-360X.2021.00528 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2021-14-6-18
1. Charka (2006): Charka Samhita, Chikitsasthanam 19/51, Chakarpanidatta,‘vidyotini’ hindi commentary, edited by Dr. Gangasahaya Pandeya, A.M.S., Chaukhambha Sanskrit Sansthan, Reprint Edition 2006, page no. 461.
2. Vaidya Laksmipati Sastri (2010): Yogratnakara, pitaatisarchiktsa 3/9, ‘vidyotini hindi commentary, edited by Bhisagatna Brahmasakar Sastri, Chaukhambha Prakshan, Reprint Edition 2010, page no. 263-264.
3. Shri Nagindas Dhamanlal Shah Rasvaidhen (1999,2005): Bharat Bhaishajya Ratnakar, fifth part, Chikitsasthanam 8809, edited by Shri Vaid Gopinath Bhishgratnen Kritya, Shri Jain Publishers, New Delhi, page no. 560.
4. Kaviraj Govind Das Sen (2012): Bhaisajya Ratnavali, atisaaradhikar 7/44, ‘Siddhipradha’ hindi Commentary, Chaukhambha Sanskrit Sansthan, edition 2012, page no. 240.
5. Anonymous (2007): The Ayurvedic Pharmacopoeia of India, Appendix-2-3-4, Published by Government of India Ministry of Health & Family Welfare, Department of AYUSH.
6. Martin Alfred, Swarbrick James, Cammarata Arthur (1991): Physical Pharmacy, physical chemical principles in pharmaceutical sciences, 3rd edition, Indian edition, Varghese Publishing House, page no. 512-519
7. Evans W.C. (2004): Trease and Evans, Pharmacognosy, 15th edition, published 2002, reprint 2004, page no. 334-338.
8. Anonymous, Protocol for Testing Ayurvedic, Siddha and Unani Medicine, Pharmacopoeial Laboratory for Indian Medicine, Government of India, Ministry of Health and Family Welfare, Department of Ayush, Ghaziabad, page no. 21, 40-50.
9. Kokate C.K (2008): Purohit A.P., Gokhale S.B., Pharmacognosy, Nirali Prakashan, 42 edition, September 2008, page no. 13.1-13.90.
10. Singh S, Machawal L, Chauhan M.G. Pharmacognostic study of male leaves of Trichosanthes dioica Roxb. with special emphasis on microscopic technique Journal of Pharmacognosy and Phytotherapy Vol. 2(5), pp. 71-75, July 2010
11. Singh S, Chauhan M.G, Machawal L Trichosanthes dioica Roxb.: Pharmacognostic standardization of the female leaves with special emphasis on the microscopic technique J Pharm Bio Allied Sciences 3(2): 249–252 Apr-Jun; 2011