Author(s): Kottakki Naveen Kumar, Karteek Rao Amperayani, Uma Devi Parimi


DOI: 10.52711/0974-360X.2021.00819   

Address: Kottakki Naveen Kumar1, Karteek Rao Amperayani2, Uma Devi Parimi2*
1Department of Chemistry, GITAM University, Visakhapatnam - 45. Andhra Pradesh. India.
2Department of Chemistry, GVP Degree and PG College, Visakhapatnam - 45 Andhra Pradesh. India.
*Corresponding Author

Published In:   Volume - 14,      Issue - 9,     Year - 2021

A new series of piperazine-1, 3, 4-thiadiazole has been synthesized, purified and characterized with the help of their analytical and spectral data. Structures of the synthesized compounds were confirmed by IR, 1H NMR and mass spectroscopy. The potential antimicrobial effects of the synthesized compounds were investigated using Vibrio cholera and Bacillus subtilis. The newly synthesized compounds exhibited capable activities against Vibrio cholera and Bacillus subtilis and it showed minimum inhibitory concentration. In this study, few compounds showed appreciable antibacterial activity. The compound PT6 shows highly significant antibacterial and good inhibition as compared to the standard drug.

Cite this article:
Kottakki Naveen Kumar, Karteek Rao Amperayani, Uma Devi Parimi. Synthesis and Antimicrobial activity of Piperazine analogues containing [1, 3, 4] Thiadiazole ring. Research Journal of Pharmacy and Technology. 2021; 14(9):4710-4. doi: 10.52711/0974-360X.2021.00819

Kottakki Naveen Kumar, Karteek Rao Amperayani, Uma Devi Parimi. Synthesis and Antimicrobial activity of Piperazine analogues containing [1, 3, 4] Thiadiazole ring. Research Journal of Pharmacy and Technology. 2021; 14(9):4710-4. doi: 10.52711/0974-360X.2021.00819   Available on:

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