Author(s):
Shahlaa Zuhair Abdul-Majeed, Sarah A. Hamood, Ashour H. Dawood
Email(s):
shahla@esraa.edu.iq , sara.ashour@esraa.edu.iq , dr.ashouralsaedi@gmail.com
DOI:
10.52711/0974-360X.2022.00734 
Address:
Shahlaa Zuhair Abdul-Majeed*, Sarah A. Hamood, Ashour H. Dawood
Al-Esraa University College, Baghdad, Iraq.
*Corresponding Author
Published In:
Volume - 15,
Issue - 10,
Year - 2022
ABSTRACT:
The used Resveratrol-Thiadiazol derivatives (A, B, C) were prepared and characterized by 1H-13C NMR and FT-IR spectroscopies. This study used two cell lines for cytotoxicity testing: ?MCF-7 (Human Breast Cancer Cells) and WRL-68 (Human Normal Liver Cells), The result of anticancer study showed ?that derivative C had significant selectivity on MCF-7 used in this study even in very low concentration used to evaluate ?the anticancer activity while derivatives A and B showed non-significant selectivity on MCF-7 in low concentration while ?in high concentration showed small selectivity which may be negligible, this selectivity determined according to the ?comparison between: MCF-7 (Human Breast Cancer Cells) and WRL-68 (Human Normal Liver Cells).?
Cite this article:
Shahlaa Zuhair Abdul-Majeed, Sarah A. Hamood, Ashour H. Dawood. Studying the Anti-Cancer Activity of Resveratrol 1,3,4-Thiadiazol Derivatives . Research Journal of Pharmacy and Technology2022; 15(10):4377-1. doi: 10.52711/0974-360X.2022.00734
Cite(Electronic):
Shahlaa Zuhair Abdul-Majeed, Sarah A. Hamood, Ashour H. Dawood. Studying the Anti-Cancer Activity of Resveratrol 1,3,4-Thiadiazol Derivatives . Research Journal of Pharmacy and Technology2022; 15(10):4377-1. doi: 10.52711/0974-360X.2022.00734 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2022-15-10-7
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