Author(s): Christophorus Oetama Adiatmaja, Jusak Nugraha, Arie Utariani

Email(s): jusak.nugraha@yahoo.comQ

DOI: 10.52711/0974-360X.2022.00798   

Address: Christophorus Oetama Adiatmaja1, Jusak Nugraha1*, Arie Utariani2
1Clinical Pathology Department, Faculty of Medicine - Dr. Soetomo Teaching Hospital, Universitas Airlangga, Surabaya, Indonesia.
2Anesthesiology and Intensive Therapy Department, Faculty of Medicine - Dr. Soetomo Teaching Hospital, Universitas Airlangga, Surabaya, Indonesia.
*Corresponding Author

Published In:   Volume - 15,      Issue - 10,     Year - 2022


ABSTRACT:
This cross-sectional study was conducted from June 2020 to May 2021. This study recruited 86 patients with confirmed PCR positive for COVID-19 who were treated in the isolation ward of Dr. Soetomo Teaching Hospital, Surabaya, Indonesia. Examination of serum levels of IL-6, CRP, and LDH was performed on the first and the sixth day of hospital admission. Found on the first day of admission the same significant correlation between IL-6 and CRP on males and females with rs=0,475 (p<0,01) and rs=0,663 (p<0,01) respectively. Correlation between IL-6 and LDH on the first day of admission on both males and females were also significant with rs=0,403 (p<0,01) and rs=0,484 (p<0,01) respectively. IL-6 and CRP on the sixth day of admission showed significant correlation on males with rs=0,621 (p<0,01), but not on females with rs=0,120 (p=0,586). IL-6 and LDH on the sixth day of admission also showed significant correlation on males with rs=0,544 (p<0,01), but not on females with rs=0,030 (p=0,893). In conclusion, there were significant positive correlations between IL-6, CRP, and LDH on the first day of admission on both male and female subjects which showed that IL-6 was associated with inflammatory response on the acute phase of COVID-19. However, on the sixth day of admission, IL-6 showed significant positive correlations with CRP and LDH only on male subjects, but not on female subjects.


Cite this article:
Christophorus Oetama Adiatmaja, Jusak Nugraha, Arie Utariani. Correlation between Interleukin-6, CRP, and LDH in COVID-19 patients of Dr. Soetomo Teaching Hospital, Surabaya, Indonesia. Research Journal of Pharmacy and Technology 2022; 15(10):4753-7. doi: 10.52711/0974-360X.2022.00798

Cite(Electronic):
Christophorus Oetama Adiatmaja, Jusak Nugraha, Arie Utariani. Correlation between Interleukin-6, CRP, and LDH in COVID-19 patients of Dr. Soetomo Teaching Hospital, Surabaya, Indonesia. Research Journal of Pharmacy and Technology 2022; 15(10):4753-7. doi: 10.52711/0974-360X.2022.00798   Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2022-15-10-71


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