Author(s):
Lilik Eka R, Djalal Rosyidi, Dahliatul Qosimah, Indah Amalia A, Dodik Prasetyo, Agri Kaltaria A
Email(s):
lilik.eka@ub.ac.id
DOI:
10.52711/0974-360X.2022.00803 
Address:
Lilik Eka R1*, Djalal Rosyidi2, Dahliatul Qosimah2, Indah Amalia A2, Dodik Prasetyo3, Agri Kaltaria A4
1Laboratory of Animal Product Technology, Faculty of Animal Husbandry, Universitas Brawijaya, Malang, Indonesia 65145.
2Laboratory of Microbiology and Immunology, Faculty of Veterinary Medicine, Universitas Brawijaya, Malang, Indonesia 65151.
3Animal Clinic, Faculty of Veterinary Medicine, University of Brawijaya, Malang Indonesia 65151.
4Laboratory of Pharmacology, Faculty of Veterinary Medicine, Universitas Brawijaya, Malang, Indonesia 65151
*Corresponding Author
Published In:
Volume - 15,
Issue - 10,
Year - 2022
ABSTRACT:
The poultry industry was an industry that supported the nutritional needs of all individuals and the world's food needs. Coffee was a natural ingredient consisting of antioxidant molecules such as Chlorogenic Acid (CGA). This research using ISA brown chicken layer, which divided into five groups such as healthy chicken (control group (C-)), chicken infected with Salmonella enteritidis 108 CFU/ml (control group (C+)), chicken infected with S. enteritidis 108CFU/ml and extract Coffee consecutive 500, 1000 and 1500 mg/kg body weight (BW) group (T1, T2, and T3). The relative level of TCD4, CD8, and CD45 cells was performed with One way ANOVA test. The research results showed that the relative level of TCD4+, TCD8+ and TCD45+ cells in T1 and T2 groups was not significant with the negative control group. The conclusion is that extracting Coffee in the T1 and T2 groups with a 500-1000mg/kg BW dose could regulate immune cell activation in chicken infected by S. enteritidis bacteria.
Cite this article:
Lilik Eka R, Djalal Rosyidi, Dahliatul Qosimah, Indah Amalia A, Dodik Prasetyo, Agri Kaltaria A. Are there effects of Extract Coffee Robust Lampung as Immunonutrition in Chicken against Salmonellosis?. Research Journal of Pharmacy and Technology 2022; 15(10):4783-8. doi: 10.52711/0974-360X.2022.00803
Cite(Electronic):
Lilik Eka R, Djalal Rosyidi, Dahliatul Qosimah, Indah Amalia A, Dodik Prasetyo, Agri Kaltaria A. Are there effects of Extract Coffee Robust Lampung as Immunonutrition in Chicken against Salmonellosis?. Research Journal of Pharmacy and Technology 2022; 15(10):4783-8. doi: 10.52711/0974-360X.2022.00803 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2022-15-10-76
REFERENCE:
1. Aziza In. Smart Farming Untuk Peternakan Ayam. J Teknol Inf Dan Komun. 2019;9(1):36-40.
2. Chotiah S, Damayanti R. Infeksi Salmonella Enteritidis Pada Ayam Pedaging Dan Pola Resistensi Terhadap Antibiotik ( Salmonella Enteritidis Infection In Broilers And Its Resistance Against Antibiotics ). In: Seminar Nasional Teknologi Peternakan Dan Veteriner. ; 2014:612-618.
3. Ariyanti T, Supar. Peranan Salmonella Enteritidis Pada Ayam Dan Produknya. Indones Bull Anim Vet Sci. 2005;15(2):57-65. Http://New.Medpub.Litbang.Pertanian.Go.Id/Index.Php/Wartazoa/Article/View/827
4. Rizaldi A, Zelpina E. Detection Of Salmonella Sp. And Escherichia Coli On Chicken Meat At Tamiang Layang Market. Microbiol Indones. 2020;14(3):117-120. Doi:10.5454/Mi.14.3.5
5. Arwangga A., Asih Iar., Sudiarta I. Analisis Kandungan Kafein Pada Kopi Di Desa Sesaot Narmada Menggunakan Spektrofotometri Uv-Vis. J Kim. 2016;10(1):110-114.
6. Johnston Kl, Clifford Mn, Morgan Lm. Coffee Acutely Modifies Gastrointestinal Hormone Secretion And Glucose Tolerance In Humans: Glycemic Effects Of Chlorogenic Acid And Caffeine. Am J Clin Nutr. 2003;78(4):728-733. Doi:10.1093/Ajcn/78.4.728
7. Nieber K. The Impact Of Coffee On Health Author Pharmacokinetics And Mode Of Action Bioactive Components In Coffee. Planta Med. 2017;83(1):1256-1263.
8. Delabouglise A, Le Thanh Nt, Ai Xuyen Ht, Et Al. Poultry Farmer Response To Disease Outbreaks In Smallholder Farming Systems In Southern Vietnam. Elife. 2020;9:1-44. Doi:10.7554/Elife.59212
9. Priftis A, Mitsiou D, Halabalaki M, Et Al. Roasting Has A Distinct Effect On The Antimutagenic Activity Of Coffee Varieties. Mutat Res - Genet Toxicol Environ Mutagen. 2018;829-830:33-42. Doi:10.1016/J.Mrgentox.2018.03.003
10. Almeida Aap, Farah A, Silva Dam, Nunan Ea, Glória Mba. Antibacterial Activity Of Coffee Extracts And Selected Coffee Chemical Compounds Against Enterobacteria. J Agric Food Chem. 2006;54(23):8738-8743. Doi:10.1021/Jf0617317
11. Qosimah D, Rosyidi D, Radiati Le, Et Al. Immunomodulator Effect Of Robusta Lampung Coffee Extract (Coffee Canephora Var Robusta) In Layer Chicken Infected With Salmonella Enteritidis Bacteria. J Ilmu-Ilmu Peternak. 2020;30(1):69-79. Doi:10.21776/Ub.Jiip.2020.030.01.07
12. Ridwan E. Etika Pemanfaatan Hewan Percobaan Dalam Penelitian Kesehatan. J Indones Med Assos. 2013;63(3):112-116.
13. Rosyidi D, Qosimah D, Amri Ia, Et Al. Effect Of Robusta Coffee From Lampung (Coffea Canephora) To Relative Number Of Ho-1, Nrf2 And Duodenum Tissue Histopathology In Chicken. Adv Anim Vet Sci. 2020;8(4):422-427.
14. O’gorman M. Flow Cytometry Assay In Primary Immunodeficiency Disease. Springer Sci. 2018;1678:321-345. Doi:10.1007/978-1-4939-7346-0
15. Zhu J, Yamane H, Paul W. Differentiation Of Effector Cd4 T Cell Populations. Annu Rev Immunol. 2010;28:445-489. Doi:10.1146/Annurev-Immunol-030409-101212.Differentiation
16. Susanti F, Sri M, Wibawan Iwt. Respons Kekebalan Ayam Ipb D1 Yang Memiliki Gen Tlr4 Terhadap Infeksi Bakteri Salmonella Enteritidis. J Vet. 2020;21(36):208-215. Doi:10.19087/Jveteriner.2020.21.2.208
17. Bauer D, Abreu J, Jordão N, Da Rosa Js, Freitas-Silva O, Teodoro A. Effect Of Roasting Levels And Drying Process Of Coffea Canephora On The Quality Of Bioactive Compounds And Cytotoxicity. Int J Mol Sci. 2018;19(11). Doi:10.3390/Ijms19113407
18. Farah A, Monteiro M, Donangelo Cm, Lafay S. Chlorogenic Acids From Green Coffee Extract Are Highly Bioavailable In Humans. J Nutr. 2008;138(12):2309-2315. Doi:10.3945/Jn.108.095554
19. Marques V, Farah A. Chlorogenic Acids And Related Compounds In Medicinal Plants And Infusions. Food Chem. 2009;113(4):1370-1376. Doi:10.1016/J.Foodchem.2008.08.086
20. Klangpetch W. Evaluation Of Antioxidant, Anti-Pathogenic And Probiotic Growth Stimulatory Activities Of Spent Coffee Ground Polyphenol Extracts. Int Food Res J. 2017;24(5):2246-2252.
21. Choi S, Jung S, Ko Ks. Effects Of Coffee Extracts With Different Roasting Degrees On Antioxidant And Anti-Inflammatory Systems In Mice. Nutrients. 2018;10(3). Doi:10.3390/Nu10030363
22. Febrianty H, Djati M. Modulasi Sel T Cd4 Dan Cd8 Pada Spleen Ayam Arab Putih (Gallus Turcicus) Dengan Ransum Yang Mengandung Daun Pepaya (Carcica Papaya L.). J Biotropika. 2015;3(3):107-111.
23. Darmawan A, Karolina Me, Hanina H. Kadar Interferon Gamma (Ifnγ) Pada Pasien Toksoplasmosis Yang Asimptomatik. Jambi Med J “Jurnal Kedokt Dan Kesehatan.” 2019;7(1):68-72. Doi:10.22437/Jmj.V7i1.7062
24. Greenlee-Wacker Mc, Nauseef Wm. Ifn-Γ Targets Macrophage-Mediated Immune Responses Toward Staphylococcus Aureus . J Leukoc Biol. 2017;101(3):751-758. Doi:10.1189/Jlb.4a1215-565rr
25. Liang N, Kitts Dd. Role Of Chlorogenic Acids In Controlling Oxidative And Inflammatory Stress Conditions. Nutrients. 2015;8(1):1-20. Doi:10.3390/Nu8010016
26. Mardhiani Y., Yulianti H, Azhary D., Rusdiana T. Formulasi Dan Stabilitas Sediaan Serumdari Ekstrak Kopi Hijau (Coffea Canephora Var. Robusta)Sebagai Antioksidan. Indones Nat Res Pharmauchetical J. 2018;2(2).
27. Wahyuniati N, M.Imun Mi. Peran Interferon Gamma Pada Infeksi Mycobacterium Tuberculosis. J Kedokt Syiah Kuala. 2018;18(2):115-120. Doi:10.24815/Jks.V18i2.18005
28. Zhang J, Chen Hm, Ma G, Et Al. The Mechanistic Study Behind Suppression Of Gvhd While Retaining Gvl Activities By Myeloid-Derived Suppressor Cells. Leukemia. 2019;33(8):2078-2089. Doi:10.1038/S41375-019-0394-Z
29. Bevington Sl, Cauchy P, Withers Dr, Lane Pjl, Cockerill Pn. T Cell Receptor And Cytokine Signaling Can Function At Different Stages To Establish And Maintain Transcriptional Memory And Enable T Helper Cell Differentiation. Front Immunol. 2017;8(Mar). Doi:10.3389/Fimmu.2017.00204
30. Praveen Ma, Parvathy Krk, Balasubramanian P, Jayabalan R. An Overview Of Extraction And Purification Techniques Of Seaweed Dietary Fibers For Immunomodulation On Gut Microbiota. Trends Food Sci Technol. 2019;92(August):46-64. Doi:10.1016/J.Tifs.2019.08.011