Author(s): Efraim Herisman Satyaputra, Dyah Karunia, Darmawan Soetantyo, Ananto Ali Alhasyimi

Email(s): anantoali@ugm.ac.id

DOI: 10.52711/0974-360X.2022.00200   

Address: Efraim Herisman Satyaputra, Dyah Karunia, Darmawan Soetantyo, Ananto Ali Alhasyimi*
Department of Orthodontics, Faculty of Dentistry, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia.
*Corresponding Author

Published In:   Volume - 15,      Issue - 3,     Year - 2022


ABSTRACT:
Orthodontic tooth movement (OTM) results from a biological response that facilitates tooth movement. Light-emitting diode (LED) can produce a variety of beneficial biological effects. Angiogenesis plays an important role in bone remodeling; hence, the amount of blood vessels can be used as a benchmark in OTM. The objective of this study is to analyze the effects of blue LED on the amount of blood vessels visible on the tension and pressure side during OTM. This study included 48 Wistar rats that were divided into 4 groups: control group; the treatment group exposed to blue LED light for 25 seconds (T1); the treatment group exposed to blue LED light for 30 seconds (T2); and the treatment group exposed to blue LED light for 35 seconds (T3) (n = 12). An open coil spring placed on the mandibular incisors generated the orthodontic force. The amount of blood vessels present on the pressure and tension sides of the periodontal tissue was observed on histological specimens with hematoxylin–eosin staining on days 0, 3, 7, and 14 at 400× magnification. The obtained data were analyzed using two-way ANOVA followed by the post-hoc least significant different (LSD) test (P < 0.05). The amount of blood vessels on the tension and pressure sides in the T3 treatment group was higher than the other groups (P < 0.05). We conclude that exposure to blue LED increased the amount of blood vessels during OTM on the tension and pressure sides in rats.


Cite this article:
Efraim Herisman Satyaputra, Dyah Karunia, Darmawan Soetantyo, Ananto Ali Alhasyimi. Increased amount of blood vessels after blue-light-emitting diode exposure during Orthodontic tooth movement in rats. Research Journal of Pharmacy and Technology. 2022; 15(3):1196-0. doi: 10.52711/0974-360X.2022.00200

Cite(Electronic):
Efraim Herisman Satyaputra, Dyah Karunia, Darmawan Soetantyo, Ananto Ali Alhasyimi. Increased amount of blood vessels after blue-light-emitting diode exposure during Orthodontic tooth movement in rats. Research Journal of Pharmacy and Technology. 2022; 15(3):1196-0. doi: 10.52711/0974-360X.2022.00200   Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2022-15-3-43


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