Author(s): Debdoot Basu, Anant Yadav, Anita A. Mehta

Email(s): dranitalmcp@gmail.com

DOI: 10.52711/0974-360X.2022.00252   

Address: Debdoot Basu1, Anant Yadav2, Anita A. Mehta1*
1L.M. College of Pharmacy, Gujarat Technological University, Ahmedabad, Gujarat, India.
2Tej Hospital, Ahmedabad, Gujarat, India.
*Corresponding Author

Published In:   Volume - 15,      Issue - 4,     Year - 2022


ABSTRACT:
Vitamin D deficiency and cardiometabolic disorders are very much widespread in worldwide, India and Ahmedabad region of Gujarat. It was the first study conducted among Gujarati ethnic group of Ahmedabad region, India. The aim of the study was to assess the effects of vitamin D supplementation on cardiometabolic disorders with vitamin D deficiency. The study was performed as an open labeled, randomized, parallel-group, single centric and prospective design at Tej Hospital, Ahmedabad, Gujarat. The dosage regimen of vitamin D supplementation was 60,000 IU/ week for 4 weeks and then 60,000IU once a month for 12 months. Our results showed that vitamin D supplementation causes significant decrease in systolic blood pressure (SBP) at 6 and 12 months as well as significant decrease in triglycerides (TG),very low density lipoprotein (VLDL), fasting blood glucose (FBG), post prandial blood glucose (PPBG) and glycosylated haemoglobin ( HbA1c) with significant increase in 25(OH)D level in vitamin D group at 12 months as compared with non-vitamin D group .Our findings supported that vitamin D deficiency may be a potential risk factor for cardiometabolic disorders and the dosage regimen of vitamin D supplementation is enough to achieve sufficiency and maintain 25(OH)D level which ultimately causes improvement in cardiometabolic disorders.


Cite this article:
Debdoot Basu, Anant Yadav, Anita A. Mehta. Effect of Vitamin D Supplementation in patients with Cardiometabolic disorders- A Clinical Study in Ahmedabad population. Research Journal of Pharmacy and Technology. 2022; 15(4):1517-2. doi: 10.52711/0974-360X.2022.00252

Cite(Electronic):
Debdoot Basu, Anant Yadav, Anita A. Mehta. Effect of Vitamin D Supplementation in patients with Cardiometabolic disorders- A Clinical Study in Ahmedabad population. Research Journal of Pharmacy and Technology. 2022; 15(4):1517-2. doi: 10.52711/0974-360X.2022.00252   Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2022-15-4-18


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