Author(s): Touahria Tatou, Rahmani Zehour, Rahmani Zineb, Abid Asma, Belguidoum Mahdi, Bensaci Cheyma


DOI: 10.52711/0974-360X.2022.00660   

Address: Touahria Tatou1, Rahmani Zehour2*, Rahmani Zineb1, Abid Asma1, Belguidoum Mahdi1, Bensaci Cheyma1
1Laboratoire de Valorisation et Promotion des Ressources Sahariennes.
2Department of Chemistry, Faculty of Mathematics and Material Sciences. University Kasdi Merbah, Ouargla (30000), Algeria.
*Corresponding Author

Published In:   Volume - 15,      Issue - 9,     Year - 2022

The present investigation is aimed at screening the bioactive compounds present in the leaves of Pergularia tomentosa L. an important ethnomedicinal plant. The qualitative analysis for the present phytochemicals was performed using MeOH/H2O extracts. Phytochemical analysis showed the existence of some primary and secondary metabolites, phenolic, flavonoids, cardenolides, tannins, alkaloids, quinones, terpenoids and glycoside; leaves contained the highest amounts of all these compounds. The highest total phenolic content and total tannins was observed in aqueous extract which is 2.59±0.49 mg GAE/g DW and 0.436±0.00 mg CE/g DW respectively. In addition, the highest total flavonoid content was observed in butanol extract which is 0.486±0.01mg QE/g DW. Reducing power assay and DPPH were employed to measure antioxidant activity in vitro, extracts were the most powerful antioxidants for the two-assay in vitro system. In addition, we investigated in vitro anti-diabetic activity of different extracts. The dichloromethane extract of Pergularia tomentosa L. showed strong antidiabetic antidiabetic activity.

Cite this article:
Touahria Tatou, Rahmani Zehour, Rahmani Zineb, Abid Asma, Belguidoum Mahdi, Bensaci Cheyma. A Phytochemical Analysis, Antioxidant and Antidiabetic activities in vitro of Pergularia tomentosa L. leaves. Research Journal of Pharmacy and Technology. 2022; 15(9):3941-6. doi: 10.52711/0974-360X.2022.00660

Touahria Tatou, Rahmani Zehour, Rahmani Zineb, Abid Asma, Belguidoum Mahdi, Bensaci Cheyma. A Phytochemical Analysis, Antioxidant and Antidiabetic activities in vitro of Pergularia tomentosa L. leaves. Research Journal of Pharmacy and Technology. 2022; 15(9):3941-6. doi: 10.52711/0974-360X.2022.00660   Available on:

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