Author(s):
Rajkumari, Vidhu Aeri, Meenakshi Sharma
Email(s):
rajkataria80@gmail.com
DOI:
10.52711/0974-360X.2022.00684 
Address:
Dr. Rajkumari, Dr. Vidhu Aeri, Mrs. Meenakshi Sharma
1Associate Professor (Pharmacognosy), Department of Pharmacognosy, I.T.S College of Pharmacy,
Delhi – Meerut Road, Murad Nagar, Ghaziabad, Uttar Pradesh, India.
2Professor (Pharmacognosy), Department of Pharmacognosy, School of Pharmaceutical Education and Research, Jamia Hamdard (Hamdard University), Dr Ambedkar Nagar, New Delhi, India.
3Assistant Professor (Pharmacognosy), Department of Pharmacognosy, I.T.S College of Pharmacy,
Delhi – Meerut Road, Murad Nagar Ghaziabad, Uttar Pradesh, India.
*Corresponding Author
Published In:
Volume - 15,
Issue - 9,
Year - 2022
ABSTRACT:
Background: Cichorium intybus Linn., belonging to Compositae family is a common drug found in India. It is traditionally used in the treatment of inflammation, cancer, viral, bacterial fungal infections and liver toxicity. This plant also has power to stimulate the immune system. Aim: Here in the paper an attempt has been made to determine the authenticity of C.intybus stem by means of Pharmacognostical and Phytochemical analysis. Methods: Macroscopy, microscopy, powder analysis, physicochemical properties, preliminary phytochemical analysis and TLC of different extracts of stem were done. Result: Microscopy of stem showed all typical features of the species Cichorium intybus Linn., The physicochemical study showed the highest extractive value with alcohol. Preliminary phytochemical confirmed the positive chemical test for Flavanoids, Alkaloids, Sterols, Carbohydrates, Resins, Phenolics and Glycosides in various extracts.
Cite this article:
Rajkumari, Vidhu Aeri, Meenakshi Sharma. Preliminary Pharmacognostical and Phytochemical Evaluation of stem of Cichorium intybus Linn. (Chicory). Research Journal of Pharmacy and Technology. 2022; 15(9):4078-2. doi: 10.52711/0974-360X.2022.00684
Cite(Electronic):
Rajkumari, Vidhu Aeri, Meenakshi Sharma. Preliminary Pharmacognostical and Phytochemical Evaluation of stem of Cichorium intybus Linn. (Chicory). Research Journal of Pharmacy and Technology. 2022; 15(9):4078-2. doi: 10.52711/0974-360X.2022.00684 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2022-15-9-44
REFERENCES:
1. Ali, M.Text book of Pharmacognosy, CBS Publisher and Distributors, Shahdara, Delhi,1-16;1997.
2. Anila VS, Dr. Madhu KP, Dr. Jyolsna G Krishna, Preliminary pharmacognostical and phytochemical evaluation of Pahysalis minima Linn. Journal of Pharmacognosy and Phytochemistry. 2019; 8(1):67-71.
3. Rasheeduz Zafar, S. Mujahid Ali. Anti- hepatotoxic effects of root and root callus extracts of Cichorium intybus. Journal of Ethanopharmacology.1998, 63; 227-231.
4. Roohi Zaman, Sadiya Noorul Basar. A Review Article of Beekhe Kasni (Cichorium intybus) its Traditional uses and Pharmacological Actions. Research Journal of Pharmaceutical Sciences. 2013 Sept 2(8), 1-4.
5. Anonymous, Standardisation of Single drugs of Unani medicine Part I, CCRUM, New Delhi, 156-161; 1987.
6. Shailja Choudhary, Hemlata Kaurav, Gitika Chaudhary. Kasani beej (Cichorium intybus): Ayurvedic View, Folk View, Phytochemistry and Modern Therapeutic Uses. International Journal for Research in Applied Sciences and Biotechnology. 2021 Mar; 8(2): 114-125.
7. Ghamarian, A, Abdollahi, M, Su, X, Amiri, A, Ahadi, A, Nowrouzi, A. Effect of chicory seed extract on glucose tolerance test (GTT) and metabolic profile in early and late stage diabetic rats DARU. Journal of Pharmaceutical Sciences. 2012; 20(1):1-9.
8. Kaskoos, R. A. Antidiabetic activity of Cichorium intybus L. seeds on STZ-induced diabetic rats. International Research Journal Pharm, 2012;3(5), 161-4.
9. Schumacher, E., Vigh, É., Molnár, V., Kenyeres, P., Fehér, G., Késmárky, G., Garai, J. Thrombosis preventive potential of chicory coffee consumption: a clinical study. Phytotherapy Research. 2011; 25(5): 744-8.
10. Jurgoński, A., Juśkiewicz, J., Zduńczyk, Z., Król, B. Caffeoylquinic acid-rich extract from chicory seeds improves glycemia, atherogenic index, and antioxidant status in rats. Nutrition. 2012; 28(3), 300-6.
11. Ahmad, B., Bawa, S., Siddiqui, A. B., Alam, T., and Khan, S. A. (2002). Components from seeds of Cichorium intybus Linn. Indian Journal of Chemistry. 2002; 41 B (12), 2701-5.
12. Iyer, S. R. Indian Medicinal Plants-a compendium of 500 species. Orient Longman, Hyderabad, India. 1994
13. Munawar, T., Bibi, Y.,Ahmad, F. (2020). Ethnomedicinal Study of Plants used for Neurodegenerative Diseases: A Review: Ethnomedicinal study of plants used for Neurodegenerative Diseases. Proceedings of the Pakistan Academy of Sciences: B. Life and Environmental Sciences, 57(3), 13- 26.
14. Wilson, R. G., Smith, J. A., & Yonts, C. D. Chicory root yield and carbohydrate composition is influenced by cultivar selection, planting, and harvest date. Crop Science. 2004; 44(3), 748-52.
15. Gibson, G.R., M.B. Roberfroid. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. Journal of Nutrition. 1995; 125:1401-12
16. Peters, A. M., Van Amerongen, A. Relationship between levels of sesquiterpene lactones in chicory and sensory evaluation. Journal of the American Society for Horticultural Science. 1998; 123(2), 326-9.
17. Kokate, C. K., Purohit, A. P., and Gokhale, S. B. Pharmacognosy, Nirali Prakashan. India. 2005.
18. Nandagopal, S., Kumari, B. R. Phytochemical and antibacterial studies of Chicory (Cichorium intybus L.)-A multipurpose medicinal plant. Advances in Biological Research. 2007; 1(1-2): 17-21.
19. De Kraker, J. W., Franssen, M. C., De Groot, A., König, W. A., Bouwmeester, H. J. (+)- Germacrene A biosynthesis: The committed step in the biosynthesis of bitter sesquiterpene lactones in chicory. Plant physiology. 1998; 117(4): 1381-1392.
20. Anonymous; Indian Pharmacopoeia. Government of India. New Delhi. 1996.
21. T.P.O’ Brien, N. Feder M.E.Mc- Cull; Protoplasm. 59; 364-73. 1964.
22. J.E.Sass. Element of Biotanical Microtechnique Mc. Graw Hill Book Co., New York. 222; 1940.
23. K.Peach, M.V.Tracy. Modern Methods of Plant Analysis. Springer-Verlag, Heidelberg. 1955.
24. C.J.Kokoshi, R.J.Kokoshi, P.J.Sharma. Journal of Americam Pharmaceutical Association., 1958; 47: 715-17.
25. Anonymous; Quality Control Methods for Medicinal Plant Material. World Health Organization. Geneva, 1998.
26. E.Stahl. Thin Layer Chromatography, A Laboratory, Handbook, Springer, New York. 1969.