Author(s): Tasneem Khandekar, Nirmal Kumar Pradhan

Email(s): ,

DOI: 10.52711/0974-360X.2023.00809   

Address: Tasneem Khandekar1, Nirmal Kumar Pradhan2
1Dept. of Physiology, Hooghly Mohsin College, The University of Burdwan, Chinsurah, Hooghly, 712101, West Bengal, India.
2Dept. of Physiology, Hooghly Mohsin College, The University of Burdwan, Chinsurah, Hooghly, 712101, West Bengal, India.
*Corresponding Author

Published In:   Volume - 16,      Issue - 11,     Year - 2023

In diabetic rats, the hypoglycemic potential of an aqueous extract of Jussiaea repens (50mg/100gm body weight) was examined. The herbal extract's impact on a number of hematological indicators was also studied. Eighteen albino rats, each contain 6 rats, were placed into three groups: vehicle control, diabetes control, and supplemented group. To develop diabetes, a single i.p injection of STZ (80mg/kg body weight) was given. Hematological markers include hemoglobin (Hb), red blood cell (RBC) count, white blood cell (WBC) count, packed cell volume (PCV), lymphocytes, and neutrophils, as well as blood glucose levels and HbA1c were assessed. STZ-induced diabetic rats fed the extract had lower fasting blood glucose levels, which was statistically significant (p<0.05). The HbA1c level in the diabetic control group increased drastically, but the level in the extract-treated supplemented group reduced significantly. Hb, PCV, RBC, and WBC as well as their differentials, were significantly reduced in diabetic control rats, whereas the supplemented group recovered significantly.. These findings imply that the aqueous extract of Jussiaea repens has hypoglycemic action and overcomes the abnormalities in STZ-induced diabetic rats' blood parameters.

Cite this article:
Tasneem Khandekar, Nirmal Kumar Pradhan. The impact of Jussiaea repens aqueous extract on Hyperglycemic and Hematological markers in Diabetic male rat induced by Streptozotocin. Research Journal of Pharmacy and Technology 2023; 16(11):4999-4. doi: 10.52711/0974-360X.2023.00809

Tasneem Khandekar, Nirmal Kumar Pradhan. The impact of Jussiaea repens aqueous extract on Hyperglycemic and Hematological markers in Diabetic male rat induced by Streptozotocin. Research Journal of Pharmacy and Technology 2023; 16(11):4999-4. doi: 10.52711/0974-360X.2023.00809   Available on:

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