Author(s): Ismail Bennani, Ali Cherif Chefchaouni, Hajar Benhaddou, Madiha Chentoufi Alami, Badreddine Moukafih, Soufiane El Marrakchi, Aicha Fahry, Yassir El Alaoui, Younes Rahali, Abdeslam El Kartouti, Youssef Hafidi, Abdelkader Laatiris, Nawal Cherkaoui

Email(s): chefchaouniali@gmail.com

DOI: 10.52711/0974-360X.2023.00958   

Address: Ismail Bennani1,2, Ali Cherif Chefchaouni3,4, Hajar Benhaddou3, Madiha Chentoufi Alami5, Badreddine Moukafih1,2, Soufiane El Marrakchi1,2, Aicha Fahry3, Yassir El Alaoui3,4, Younes Rahali3,4, Abdeslam El Kartouti1, Youssef Hafidi2, Abdelkader Laatiris3, Nawal Cherkaoui3
1Department of Pharmacy, Faculty of Medicine, Pharmacy and Dental Medicine of Fez, Sidi Mohamed Ben Abdellah University, Fez, Morocco.
2Department of Pharmacy, Hassan II University Hospital of Fez, Morocco.
3Faculty of Medicine and Pharmacy, Mohammed V University of Rabat, Rabat, Morocco.
4Ibn Sina University Hospital Center, Rabat, Morocco.
5Faculty of Medicine and Pharmacy of Tangier, Abdelmalek Essaâdi University.
*Corresponding Author

Published In:   Volume - 16,      Issue - 12,     Year - 2023


ABSTRACT:
Ibuprofen is a non-steroidal anti-inflammatory drug known for its remarkable therapeutic effects. It can be available in different forms among which are coated and sugar-coated tablets.The objective of this study was to compare the dissolution profile between these two forms. The study was conducted with 5 ibuprofen drugs: 3 generics and one reference drug based on coated tablets, and one drug containing the coated tablets.The parameters used to evaluate and compare the dissolution profiles were the similarity (f2) and difference (f1) factors.The results obtained showed similar dissolution profiles for the two types of coating, with a more significant release for the sugar-coated tabletsduring the first 30 minutes.Dissolution studies are important studies to establish equivalence between generic and brand name drugs, and also to predict the release of the AP.


Cite this article:
Ismail Bennani, Ali Cherif Chefchaouni, Hajar Benhaddou, Madiha Chentoufi Alami, Badreddine Moukafih, Soufiane El Marrakchi, Aicha Fahry, Yassir El Alaoui, Younes Rahali, Abdeslam El Kartouti, Youssef Hafidi, Abdelkader Laatiris, Nawal Cherkaoui. The Influence of the coating on the release of Ibuprofen from the Tablet: Comparative Dissolution Study of the different types of coating. Research Journal of Pharmacy and Technology.2023; 16(12):5912-4. doi: 10.52711/0974-360X.2023.00958

Cite(Electronic):
Ismail Bennani, Ali Cherif Chefchaouni, Hajar Benhaddou, Madiha Chentoufi Alami, Badreddine Moukafih, Soufiane El Marrakchi, Aicha Fahry, Yassir El Alaoui, Younes Rahali, Abdeslam El Kartouti, Youssef Hafidi, Abdelkader Laatiris, Nawal Cherkaoui. The Influence of the coating on the release of Ibuprofen from the Tablet: Comparative Dissolution Study of the different types of coating. Research Journal of Pharmacy and Technology.2023; 16(12):5912-4. doi: 10.52711/0974-360X.2023.00958   Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2023-16-12-59


REFERENCES:
1.    Dhingra G, Sreelesh B, Nagpal, M., Rakha, P,Nagori B-P. In-vitro dissolution testing of ibuprofen using compendial and biorelevant dissolution media. Research Journal of Pharmacy and Technology. 2010; 3(3): 931-933.
2.    Jain A, Agarwal P, Kumawat A, Rammularjsinh R, Gautam H. Evaluation and Validated UV- Spectroscopic Method for Estimation of Ibuprofen from Marketed Tablets (Brufen400). Research J. Pharm. and Tech. 2011; 4(4): 620-623.
3.    Priyanka M. Salve, Shital V. Sonawane, Mayuri B. Patil, Rajendra K. Surawase. Dissolution and Dissolution Test Apparatus: A Review. Asian Journal of Research in Pharmaceutical Sciences. 2021; 11(3): 229-6.doi: 10.52711/2231-5659.2021.00037
4.    Gao Z. In vitro dissolution testing with flow-through method: a technical note. AAPS Pharm Sci Tech. 2009; 10(4): 1401-5. doi: 10.1208/s12249-009-9339-6.
5.    GitikaDhingra, BrindaSreelesh, ManjuNagpal, PankajRakha, B P Nagori. In-Vitro Dissolution Testing of Ibuprofen Using Compendial and Biorelevant Dissolution Media. Research J. Pharm. and Tech. 2010; 3(3): 931-933.
6.    J. SrinivasaRao, J. Naga Mallika, M. Sri Madhu Sri, G. RaveendraBabu, M. PrasadaRao, C. Gopinath. Comparative in Vitro Dissolution Assessment of Three Different Brands of Lansoprazole Capsules. Research J. Pharma. Dosage Forms and Tech. 2011; 3(2): 58-66 .
7.    K. Soumya, S. Susanna, T.E.G.K. Murthy. In vitro Dissolution Studies on Commercial Brands Containing Immediate Release Pioglitazone and Metformin Hydrochloride Extended Release Tablets. Res. J. Pharm. Dosage Form. and Tech. 2017: 9(1); 15-18.doi: 10.5958/0975-4377.2017.00003.9
8.    Naddour R-F, Kaddar N-A. In Vitro Bioequivalence for three Products of Warfarin Sodium in Syrian Market. Research J. Pharm. and Tech. 2018; 11(2): 532-536.doi: 10.5958/0974-360X.2018.00099.9
9.    Mahor P-R, Parcha V, Singh Y, Sharma R, Bhandari A. Validation of a Quantitative Method for Simultaneous Estimation and Comparison of Dissolution Method for Combination Tablet of Lamivudine and Zidovudine. Asian J. Research Chem. 2011: 4(11); 1793-1799.
10.    K. Thangavel. Effects of Dissolution of Drug’s. Research J. Pharm. and Tech. 2017; 10(9): 2923-2925. doi: 10.5958/0974-360X.2017.00516.9
11.    Keyur D. Baruwala, Shyam H. Mistry, Nrupal R. Modi, Anil G. Jadhav. A Review on Solvent less coating: Recent Advances in Pharmaceutical Coating. Research J. Pharm. and Tech. 2011; 4(6): 851-860.
12.    Shaikh, R., O’Brien, D. P., Croker, D. M., and Walker, G. M. The development of a pharmaceutical oral solid dosage forms. In Computer Aided Chemical Engineerin. 2018; 41: 27-65. Elsevier.

Recomonded Articles:

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

1.3
2021CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank

Journal Policies & Information


Recent Articles




Tags


Not Available