Maternal Mortality Rate is a serious world health problem. According to the World Health Organization in 2017 around 295,000 women died and after pregnancy and childbirth in 2018 increased to 830,000. The main cause of maternal death is preeclampsia, therefore hypertension and urine protein as causes of preeclampsia need to be controlled. Research has shown that certain nutrients can improve blood pressure and urine protein. The research objective was to analyze the effect of cassava cracker consumption on urine protein in maternity hypertension. This type of research used quasi-experimental and the populations in this study were all Maternities at Cenrana and Tompobulu Health Center. The sample was 15 pregnant women at Puskesmas Cenrana as an experimental group and 15 pregnant women at Tompobulu health center as a control group. The results of the paired t test showed that the consumption of ebi cassava crackers at fourth’s week had a significant effect on changes in urine protein in pregnant women in intervention group with a value of p> a 0.05 = 0.008, while in the control group there was no effect with a value of p> a 0, 05 = 0.250. It was concluded that consumption of ebi cassava crackers during four weeks changed the urine protein from positive to negative. Hopely, every hypertensive pregnant woman consumes cassava crackers to prevent positive urine protein.
Cite this article:
Andi Nurlinda. The Effect of Cassava-Dried Shrimp Crackers on Urine Protein in Maternity Hypertension in Maros District Health Center. Research Journal of Pharmacy and Technology 2023; 16(2):769-2. doi: 10.52711/0974-360X.2023.00131
Andi Nurlinda. The Effect of Cassava-Dried Shrimp Crackers on Urine Protein in Maternity Hypertension in Maros District Health Center. Research Journal of Pharmacy and Technology 2023; 16(2):769-2. doi: 10.52711/0974-360X.2023.00131 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2023-16-2-50
1. WHO. 2019. Maternal mortality. https://www.who.int/news-room/fact-sheets/detail/maternal-mortality.Diakses pada 20 November 2020.
2. Kementerian Kesehatan RI. 2019. Profil Kesehatan Indonesia 2018. https://www.kemkes.go.id/resources/download/pusdatin/profil-kesehatan-indonesia/profil-kesehatan-indonesia-2018.pdf. Diakses pada 20 November 2020.
3. von Dadelszen P, Magee LA. Preventing deaths due to the hypertensive disorders of pregnancy. Best Practice & Research. Clinical Obstetrics & Gynaecology. 2016;36:83-102.
4. Mol BWJ, Roberts CT, Thangaratinam S, Magee LA, de Groot CJM, Hofmeyr GJ. Pre-eclampsia. Lancet. 2016;387(10022):999-1011.
5. Mills KT, Stefanescu A, He J. The global epidemiology of hypertension. Nature Reviews. Nephrology. 2020;16(4):223-237.
6. Brown CM, Garovic VD. Drug treatment of hypertension in pregnancy. Drugs. 2014;74(3):283-296.
7. Morgan NK, Choct M. Cassava: Nutrient composition and nutritive value in poultry diets. Animal Nutrition. 2016;2(4):253-261.
8. Wong A, Viola D, Bergen D, Caulfield E, Mehrabani J, Figueroa A. The effects of pumpkin seed oil supplementation on arterial hemodynamics, stiffness and cardiac autonomic function in postmenopausal women. Complementary Therapies in Clinical Practice. 2019;37:23-26.
9. Fishel Bartal M, Lindheimer MD, Sibai BM. Proteinuria during pregnancy: definition, pathophysiology, methodology, and clinical significance. American journal of obstetrics and gynecology. 2020;S0002-9378(20):30989-3.
10. Cravedi P, Remuzzi G. Pathophysiology of proteinuria and its value as an outcome measure in chronic kidney disease. British Journal of Clinical Pharmacology. 2013;76(4):516-23.
11. Capelli I, Vitali F, Zappulo F, Martini S, Donadei C, Cappuccilli M, et al. Biomarkers of Kidney Injury in Very-low-birth-weight Preterm Infants: Influence of Maternal and Neonatal Factors. In Vivo. 2020;34(3):1333-1339.
12. Attini R, Leone F, Montersino B, Fassio F, Minelli F, Colla L, et al. Pregnancy, Proteinuria, Plant-Based Supplemented Diets and Focal Segmental Glomerulosclerosis: A Report on three cases and critical appraisal of the literature. Nutrients. 2017;9(7):770.
13. Muslim Z, Sahidan, Rahma SA. Urine protein level in pregnant women trimester second and third in Singaran Pati district of Bengkulu City. International Conference on Inter-professional Health Collaboration (ICIHC 2018). 2019.
14. Herring CM, Bazer FW, Johnson GA, Wu G. Impacts of maternal dietary protein intake on fetal survival, growth, and development. Experimental Biology and Medicine. 2018;243(6):525-533.
15. Davin JC. The glomerular permeability factors in idiopathic nephrotic syndrome. Pediatric Nephrology. 2016;31(2):207-15.
16. Oghobase GE, Aladesanmi OT, Akomolafe RO, Olukiran OS, Akano PO, Eimunjeze MH. Assessment of the toxicity and biochemical effects of detergent processed cassava on renal function of Wistar rats. Toxicology Reports. 2020;7:1103-1111.
17. Zhao CN, Meng X, Li Y, Li S, Liu Q, Tang GY, et al. Fruits for prevention and treatment of cardiovascular diseases. Nutrients. 2017;9(6):598.
18. Santhanam P, Shapiro JI, Khitan Z. Association between dietary potassium, body mass index, and proteinuria in normotensive and hypertensive individuals: Results from the modification of diet in renal disease study baseline data. Journal of Clinical Hypertension. 2017;19:558-559.
19. Sharma D, Shastri S, Sharma P. Intrauterine Growth Restriction: Antenatal and Postnatal Aspects. Clin Med Insights Pediatr. 2016;10:67-83.
20. Caldeira-Dias M, Viana-Mattioli S, de Souza Rangel Machado J, Carlström M, de Carvalho Cavalli R, Sandrim VC. Resveratrol and grape juice: Effects on redox status and nitric oxide production of endothelial cells in in vitro preeclampsia model. Pregnancy Hypertension. 2021;23:205-210.
21. Cohen JM, Beddaoui M, Kramer MS, Platt RW, Basso O, Kahn SR. Maternal antioxidant levels in pregnancy and risk of preeclampsia and small for gestational age birth: A systematic review and meta-analysis. PLoS One. 2015;10(8):e0135192.
22. Rakhshani A, Nagarathna R, Mhaskar R, Mhaskar A, Thomas A, Gunasheela S. The effects of yoga in prevention of pregnancy complications in high-risk pregnancies: a randomized controlled trial. Preventive Medicine. 2012;55(4):333-340.