Author(s):
Muhammad Miftahussurur, Camilia Metadea Aji Savitri, Yudith Annisa Ayu Rezkhita, Amie Vidyani, Dalla Doohan, Diah Priyantini, Titong Sugihartono, Yoshio Yamaoka
Email(s):
muhammad-m@fk.unair.ac.id
DOI:
10.52711/0974-360X.2023.00252 
Address:
Muhammad Miftahussurur1,2*, Camilia Metadea Aji Savitri2, Yudith Annisa Ayu Rezkhita2,3, Amie Vidyani1, Dalla Doohan2, Diah Priyantini2, Titong Sugihartono1,2, Yoshio Yamaoka1,4,5
1Gastroentero-Hepatology Division, Department of Internal Medicine, Faculty of Medicine–Dr. Soetomo Teaching Hospital, Universitas Airlangga, Surabaya 60286, Indonesia.
2Helicobacter pylori and Microbiota Study Group, Institute of Tropical Disease, Universitas Airlangga, Surabaya 60115, Indonesia.
3Department of Internal Medicine, Faculty of Medicine, Universitas Muhammadiyah Surabaya, Surabaya 60113, Indonesia.
4Department of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Yufu 879-5593, Japan.
5Department of Medicine, Gastroenterology and Hepatology Section, Baylor College of Medicine, Houston, TX 77030, USA.
*Corresponding Author
Published In:
Volume - 16,
Issue - 3,
Year - 2023
ABSTRACT:
Colorectal cancer patients have been experiencing various side effects related to the therapies, both physically and physiologically. Complementary medicine was used to help patients alleviate complaints and increase their quality of life. This systematic review aimed to sort out complementary medicines that could be advised to be used for colorectal cancer patients. Search limitations include the population of colorectal cancer patients, published between 2015 and 2021 and written in English. We found that traditional Chinese medicine, aromatherapy massage, acupuncture, and mindfulness-based stress reduction tests were beneficial in improving patients’ physical and physiological complaints. However, dosing and herb-herb interactions in Chinese traditional medicine and the beneficial persistency effect of other modalities needed further investigation, especially in colorectal cancer patient therapy. Complementary modalities are generally safe; however, some therapies still warrant further investigation to confirm safety and beneficial consistency.
Cite this article:
Muhammad Miftahussurur, Camilia Metadea Aji Savitri, Yudith Annisa Ayu Rezkhita, Amie Vidyani, Dalla Doohan, Diah Priyantini, Titong Sugihartono, Yoshio Yamaoka. A Systematic Review of Complementary Therapies in Colorectal cancer patients: Summarizing the Current Global Options. Research Journal of Pharmacy and Technology 2023; 16(3):1540-6. doi: 10.52711/0974-360X.2023.00252
Cite(Electronic):
Muhammad Miftahussurur, Camilia Metadea Aji Savitri, Yudith Annisa Ayu Rezkhita, Amie Vidyani, Dalla Doohan, Diah Priyantini, Titong Sugihartono, Yoshio Yamaoka. A Systematic Review of Complementary Therapies in Colorectal cancer patients: Summarizing the Current Global Options. Research Journal of Pharmacy and Technology 2023; 16(3):1540-6. doi: 10.52711/0974-360X.2023.00252 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2023-16-3-88
REFERENCES:
1. Mármol I, Sánchez-de-Diego C, Pradilla Dieste A, Cerrada E, Rodriguez Yoldi MJ. Colorectal Carcinoma: A General Overview and Future Perspectives in Colorectal Cancer. Int J Mol Sci. 2017 Jan;18(1):197. https://doi.org/10.3390%2Fijms18010197
2. Wong CH, Sundberg T, Chung VC, Voiss P, Cramer H. Complementary medicine use in US adults with a history of colorectal cancer: a nationally representative survey. Support Care Cancer. 2021;29(1):271–8. https://doi.org/10.1007/s00520-020-05494-x
3. Chan K, Lui L, Yu K, Lau K, Lai M, Lau W, et al. The efficacy and safety of electro-acupuncture for alleviating chemotherapy-induced peripheral neuropathy in patients with colorectal cancer: Study protocol for a single-blinded, randomized sham-controlled trial. Trials. 2020;21(1):1–9. https://doi.org/10.1186/s13063-019-3972-5
4. Kong M yan, Li L yan, Lou Y mei, Chi H yu, Wu J jun. Chinese herbal medicines for prevention and treatment of colorectal cancer: From molecular mechanisms to potential clinical applications. J Integr Med. 2020;18(5):369–84. https://doi.org/10.1016/j.joim.2020.07.005
5. Qureshi M, Zelinski E, Carlson LE. Cancer and Complementary Therapies: Current Trends in Survivors’ Interest and Use. Integr Cancer Ther. 2018;17(3):844–53. https://doi.org/10.1177/1534735418762496
6. Zhang MF, Wen YS, Liu WY, Peng LF, Wu XD, Liu QW. Effectiveness of Mindfulness-based Therapy for Reducing Anxiety and Depression in Patients with Cancer. Med (United States). 2015;94(45):e897. https://doi.org/10.1097/md.0000000000000897
7. Li W, Li C, Zheng H, Chen G, Hua B. Therapeutic targets of Traditional Chinese Medicine for colorectal cancer. J Tradit Chin Med. 2016;36(2):243–9. https://doi.org/10.1016/s0254-6272(16)30034-6
8. Xu Y, Mao JJ, Sun L, Yang L, Li J, Hao Y, et al. Association between use of Traditional Chinese Medicine herbal therapy and survival outcomes in patients with stage II and III colorectal cancer: A multicenter prospective cohort study. J Natl Cancer Inst - Monogr. 2017;2017(52):19–25. https://doi.org/10.1093/jncimonographs/lgx015
9. Wu CT, Tsai YT, Lai JN. Demographic and medication characteristics of traditional Chinese medicine users among colorectal cancer survivors: A nationwide database study in Taiwan. J Tradit Complement Med. 2017;7(2):188–94. https://doi.org/10.1016/j.jtcme.2016.07.001
10. Liu Y, May BH, Zhang AL, Guo X, Lu C, Xue CC, et al. Acupuncture and Related Therapies for Treatment of Postoperative Ileus in Colorectal Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evidence-based Complement Altern Med. 2018;2018:3178472. https://doi.org/10.1155/2018/3178472
11. Ayik C, Özden D. The effects of preoperative aromatherapy massage on anxiety and sleep quality of colorectal surgery patients: A randomized controlled study. Complement Ther Med. 2018;36(November 2017):93–9. https://doi.org/10.1016/j.ctim.2017.12.002
12. Lu Y, Qu HQ, Chen FY, Li XT, Cai L, Chen S, et al. Effect of Baduanjin Qigong Exercise on Cancer-Related Fatigue in Patients with Colorectal Cancer Undergoing Chemotherapy: A Randomized Controlled Trial. Oncol Res Treat. 2019;42(9):431–8. https://doi.org/10.1159%2F000501127
13. Black DS, Peng C, Sleight AG, Nguyen N, Lenz H-J, Figueiredo JC. Mindfulness Practice Reduces Cortisol Blunting During Chemotherapy: A Randomized Controlled Study of Colorectal Cancer Patients. Cancer. 2017;123(6):3088–97. https://doi.org/10.1002/cncr.30698
14. Luo Q, Asher GN. Complementary and Alternative Medicine Use at a Comprehensive Cancer Center. Integr Cancer Ther. 2017;16(1):104–9. https://doi.org/10.1177/1534735416643384
15. Qian Q, Chen W, Cao Y, Cao Q, Cui Y, Li Y, et al. Targeting Reactive Oxygen Species in Cancer via Chinese Herbal Medicine. Oxid Med Cell Longev. 2019;2019:9240426. https://doi.org/10.1155/2019/9240426
16. Perillo B, Di Donato M, Pezone A, Di Zazzo E, Giovannelli P, Galasso G, et al. ROS in cancer therapy: the bright side of the moon. Exp Mol Med. 2020;52(2):192–203. https://doi.org/10.1038/s12276-020-0384-2
17. Hu X-Q, Sun Y, Lau E, Zhao M, Su S-B. Advances in Synergistic Combinations of Chinese Herbal Medicine for the Treatment of Cancer. Curr Cancer Drug Targets. 2016;4(16):346–56. https://doi.org/10.2174/1568009616666151207105851
18. Lau CHY, Wu X, Chung VCH, Liu X, Hui EP, Cramer H, et al. Acupuncture and related therapies for symptom management in palliative cancer care: Systematic review and meta-analysis. Med (United States). 2016;95(9):e2901. https://doi.org/10.1097/md.0000000000002901
19. Wu X, Chung VCH, Hui EP, Ziea ETC, Ng BFL, Ho RST, et al. Effectiveness of acupuncture and related therapies for palliative care of cancer: Overview of systematic reviews. Sci Rep. 2015;5(March):1–15. https://doi.org/10.1038/srep16776
20. Tao WW, Jiang H, Tao XM, Jiang P, Sha LY, Sun XC. Effects of Acupuncture, Tuina, Tai Chi, Qigong, and Traditional Chinese Medicine Five-Element Music Therapy on Symptom Management and Quality of Life for Cancer Patients: A Meta-Analysis. J Pain Symptom Manage. 2016;51(4):728–47. https://doi.org/10.1016/j.jpainsymman. 2015.11.027
21. Valois B De, Glynne-jones R. Acupuncture in the Supportive Care of Colorectal Cancer Survivors : Four Case Studies , Part 1. 2018;(March). Available at: https://www.researchgate.net/ publication/323727394
22. Khiewkhern S, Promthet S, Sukprasert A, Eunhpinitpong W, Bradshaw P. Effectiveness of aromatherapy with light thai massage for cellular immunity improvement in colorectal cancer patients receiving chemotherapy. Asian Pacific J Cancer Prev. 2013;14(6):3903–7. https://doi.org/10.7314/apjcp.2013.14.6.3903
23. Armstrong M, Flemming K, Kupeli N, Stone P, Wilkinson S, Candy B. Aromatherapy, massage and reflexology: A systematic review and thematic synthesis of the perspectives from people with palliative care needs. Palliat Med. 2019;33(7):757–69. https://doi.org/10.1177/0269216319846440
24. Boehm K, Büssing A, Ostermann T. Aromatherapy as an Adjuvant Treatment in Cancer Care- A Descriptive Systematic Review. Complement Altern Med. 2012;9(4):503–18. https://doi.org/10.4314/ajtcam.v9i4.7
25. Priscilla MK, Santha DNJ, Priscilla MK. Massage Therapy- Complementary and Alternative Therapeutic approach. Asian J Nurs Educ Res. 2014;4(4):514–7. Available at: https://ajner.com/AbstractView.aspx?PID=2014-4-4-25
26. Joy RAP. Effect of Foot Reflexology on Pain among Cancer Patients in Oncology Ward , Sri Ramakrishna Hospital , Coimbatore . Asian J Nur Edu Res [Internet]. 2011;1(4):107–8. Available from: https://ajner.com/AbstractView.aspx?PID=2011-1-4-14
27. Doss JJ. Effectiveness of Foot Massage on Pain Among Cancer Patients at Selected Hospitals, Salem. Asian J Nur Edu Res. 2014;4(June):228–31. Available at: https://ajner.com/AbstractView.aspx?PID=2014-4-2-16
28. Joseph V, Joseph J. Effectiveness of aromatherapy and quality of sleep among elderly inmates of selected old age home. Asian J Nurs Educ Res. 2016;6(4):511. http://dx.doi.org/10.5958/2349-2996.2016.00096.3
29. Indra V. A study to assess the effectiveness of Aromatherapy during First Stage of Labour among women in Selected Hospitals, Puducherry. Asian J Nurs Educ Res. 2017;7(4):495. http://dx.doi.org/10.5958/2349-2996.2017.00096.9
30. Wayne PM, Lee MS, Novakowski J, Osypiuk K, Ligibel J, Carlson LE, et al. Tai Chi and Qigong for cancer-related symptoms and quality of life: A systematic review and meta-analysis. J Cancer Surviv. 2018;12(2):256–67. https://doi.org/10.1007/s11764-017-0665-5
31. Oh B, Bae K, Lamoury G, Eade T, Boyle F, Corless B, et al. The Effects of Tai Chi and Qigong on Immune Responses: A Systematic Review and Meta-Analysis. Medicines. 2020;7(7):39. https://doi.org/10.3390%2Fmedicines7070039
32. Xie C, Dong B, Wang L, Jing X, Wu Y, Lin L, et al. Mindfulness-based stress reduction can alleviate cancer- related fatigue: A meta-analysis. J Psychosom Res. 2020;130(August 2019):109916. https://doi.org/10.1016/j.jpsychores.2019.109916. https://doi.org/10.5958/2349-2996.2016.00034.3
33. Rama RGN. A Study to assess the Effectiveness of Mindfulness Based Stress Reduction Meditation on Reducing Stress among Cancer Patients in Selected Hospitals at Mandya District. Asian J Nurs Educ Res. 2016;6(2):188.
34. Suh H-W, Jeong HY, Hong S, Kim JW, Yoon SW, Lee JY, et al. The mindfulness-based stress reduction program for improving sleep quality in cancer survivors: A systematic review and meta-analysis. Complement Ther Med. 2021;57:102667. https://doi.org/10.1016/j.ctim.2021.102667