Author(s): Himanshi Dahiya, Kumari Sonia, Sanjit Boora, Suman Yadav, Sulochana Kaushik, Sandeep Singh, Jaya Parkash Yadav, Samander Kaushik

Email(s): samanderkaushik@gmail.com

DOI: 10.52711/0974-360X.2023.00541   

Address: Himanshi Dahiya1, Kumari Sonia1, Sanjit Boora1, Suman Yadav1, Sulochana Kaushik2, Sandeep Singh3, Jaya Parkash Yadav2, Samander Kaushik1*
1Centre for Biotechnology, Maharshi Dayanand University, Rohtak (Hr), India.
2Department of Genetics, Maharshi Dayanand University, Rohtak (Hr), India.
3Department of Biochemistry, Maharshi Dayanand University, Rohtak (Hr), India.
*Corresponding Author

Published In:   Volume - 16,      Issue - 7,     Year - 2023


ABSTRACT:
Medicinal plants have many secondary metabolites, making them a good source of medication or therapeutic agents. Medicinal plants or their parts can be the only source of treatment or effective management for various life-threatening infections. Phytomedicines are safer than chemical-based therapeutic agents due to their lower risk of side effects. Medicinal plant-based therapeutics therapy is rapid, sensitive, specific, economical, and readily available for all; therefore, ethnomedicine is gaining more interest worldwide. According to the World Health Organization (WHO), around 4000 million people regularly utilize medicinal plants to treat various illnesses. Allopathic drugs are accessible throughout the World. Medicinal herbs are still widely used, attributable to public trust in their therapeutic usefulness in many regions of the World. Almost 2000 ethnic groups have their traditional medical systems across the World. Ayurveda is one of India's most well-known ancient medical systems that has persevered and flourished over the centuries. Herbal products have been successfully employed in health treatment since ancient times. Trachyspermum ammi L. (Ajwain) is one of the famous medicinal plants belonging to the family Apiaceae. Trachyspermum ammi is a native plant to Egypt. Trachyspermum ammi is a popular seed spice crop in India. Trachyspermum ammi contains various bioactive components that have long been recognized for their medicinal and antimicrobial products. The present review describes the botanical, phytochemical, ethnomedicinal, and pharmacological information related to Trachyspermum ammi.


Cite this article:
Himanshi Dahiya, Kumari Sonia, Sanjit Boora, Suman Yadav, Sulochana Kaushik, Sandeep Singh, Jaya Parkash Yadav, Samander Kaushik. Trachyspermum ammi (Ajwain): A Sacred plant with High Medicinal and Therapeutic potential. Research Journal of Pharmacy and Technology 2023; 16(7):3285-8. doi: 10.52711/0974-360X.2023.00541

Cite(Electronic):
Himanshi Dahiya, Kumari Sonia, Sanjit Boora, Suman Yadav, Sulochana Kaushik, Sandeep Singh, Jaya Parkash Yadav, Samander Kaushik. Trachyspermum ammi (Ajwain): A Sacred plant with High Medicinal and Therapeutic potential. Research Journal of Pharmacy and Technology 2023; 16(7):3285-8. doi: 10.52711/0974-360X.2023.00541   Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2023-16-7-38


REFERENCES:
1.    Morshed S. Alam MK. Begum A. Shahriar SM. Sharmin KN. Akther S. Physicochemical properties and chemical constituents of oil from Joan Seed (Trachyspermum ammi L). Journal of Environmental Science and Natural Resources. 2012;5(2):15-21.https://doi.org/10.3329/jesnr.v5i2.14571
2.    Azhar N. Hussain B. Ashraf MY. Abbasi KY. Water stress-mediated changes in growth, physiology and secondary metabolites of desi ajwain (Trachyspermum ammi L.). Pakistan Journal of Botany. 2011 Dec 1;43(1):15-19.
3.    Gersbach PV. Reddy N. Non-invasive localization of thymol accumulation in Carum copticum (Apiaceae) fruits by chemical shift selective magnetic resonance imaging. Annals of Botany. 2002;90(2):253-257. https://doi.org/10.1093/aob/mcf179
4.    Pruthi JS. Quick freezing preservation of foods: foods of plant origin. First Edition. Mumbai. Allied Publishers; 1999.
5.    Mishra S. A Review of Super Food Ajwain and Its Pharmacological Actions. International Journal of Research in Pharma & Pharmaceutical Science. 2020;1(1):30-33.
6.    Anilakumar KR. Saritha V. Khanum F. Bawa AS. Ameliorative effect of ajwain extract on hexachlorocyclohexane-induced lipid peroxidation in rat liver. Food and Chemical Toxicology. 2009;47(2):279-282.
7.    Jan SA. Shinwari ZK. Zeb A. Khalil AT. Shah SH. Ethnobotany and research trends in Trachyspermum ammi L.(Ajowan); A popular folklore remedy. American-Eurasian Journal of Agricultural & Environmental Sciences. 2015;15:68-73.
8.    Eftekhari M. Hoseinsalari A. Mansourian M. Farjadmand F. Shams Ardekani MR. Sharifzadeh M. Hassanzadeh G et al. Trachyspermum ammi (L.) Sprague, superb essential oil and its major components on peptic ulcers: in vivo combined in silico studies. DARU Journal of Pharmaceutical Sciences. 2019 Jun;27(1):317-327. https://dx.doi.org/10.1007%2Fs40199-019-00279-y
9.    Khan S. Shameem I. Sahibole S. Siddiqui A. Trachyspermum ammi: ancient Unani medicine for a modern cure, a review of potential therapeutic applications. World Journal of Pharmaceutical Research. 2016;5(12):169-178. http://dx.doi.org/10.20959/wjpr201612-6875
10.    Khare CP. Indian medicinal plants- An illustrated dictionary. New Delhi: Springer; 2007; 56-57, 486-487, 665, 674, 694.
11.    Yadav R. Chandan KP. Deepika G. Rahul K. Health benefits of Indian aromatic plant ajwain (Trachycpermum ammi). International Journal of Pharmacy & Technology. 2011;3(3):1356-1366.
12.    Joshi S. Medicinal plants. 1st ed. Delhi: Oxford and IBH Publisher; 2000.
13.    Shankaracharya NB. Nagalakshmi S. Naik JP. Rao LJ. Studies on chemical and technological aspects of ajowan (Trachyspermum ammi (L.) syn. Carum copticum Hiern) seeds. Journal of Food Science and Technology. 2000;37(3):277-281.
14.    Ishikawa T. Sega Y. Kitajima J. Water-soluble constituents of ajowan. Chemical and Pharmaceutical Bulletin. 2001;49(7):840-844.
15.    Damodar K. Bhogineni S. Ramanjaneyulu B. Phytochemical screening, quantitative estimation of total phenolic, flavanoids, and antimicrobial evaluation of Trachyspermum ammi. Journal of Atoms and Molecules. 2011;1(1):1.
16.    Chopra RN. Chopra IC. Indigenous drugs of India. Academic Publishers; 1994.
17.    Garg SN. Kumar S. A new glucoside from Trachyspermum ammi. Fitoterapia (Milano). 1998;69(6):511-2.
18.    Choudhury S. Ahmed R. Kanjilal PB. Leclercq PA. Composition of the seed oil of Trachyspermum ammi (L.) Sprague from Northeast India. Journal of essential oil research. 1998;10(5):588-90.
19.    Garg SK. Sharma ND. Gupta SR. phenolic glucoside from the seeds of Carum copticum. Phytochemistry. 1980;19(10):2215-2216.
20.    Mohagheghzadeh A. Faridi P. Ghasemi Y. Carum copticum Benth. & Hook., essential oil chemotypes. Food Chemistry. 2007;100(3):1217-9.
21.    Moein MR. Zomorodian K. Pakshir K. Yavari F. Motamedi M. Zarshenas MM. Trachyspermum ammi (L.) Sprague: Chemical Composition of Essential Oil and Antimicrobial Activities of Respective Fractions. Journal of Evidence-Based Complementary & Alternative Medicine.2015;20(1)50-56. doi:10.1177/2156587214553302
22.    Pathak AK. Nainwal N. Goyal BM. Singh R. Mishra V. Nayak S. Bansal P. Gupta V. Pharmacological activity of Trachyspermum ammi: a review. Journal of Pharmacy Research. 2010;3(4):895-9.
23.    Jan SA. Shinwari ZK. Zeb A. Khalil AT. Shah SH. Ethnobotany and research trends in Trachyspermum ammi L. (Ajowan); A popular folklore remedy. American-Eurasian Journal of Agricultural & Environmental Sciences. 2015;15:68-73.
24.    Monfared AA. Mousavi SA. Zomorodian K. Mehrabani D. Iraji A. Moein MR. Trachyspermum ammi aromatic water: A traditional drink with considerable anti-Candida activity. Current Medical Mycology. 2020;6(3):1.doi: 10.18502/cmm.6.3.3979. PMID: 33834136; PMCID: PMC8018821.
25.    Kaushik S. Kaushik S. Sharma Y. Kumar R. Yadav JP. The Indian perspective of COVID-19 outbreak. Virus Disease. 2020;31(2):146–53. doi: 10.1007/s13337-020-00587-x.
26.    Sharma V. Kaushik S. Kumar R. Yadav JP. Kaushik S. Emerging trends of Nipah virus: a review. Reviews in Medical Virology. 2019;29:e2010. DOI: 10.1002/rmv.2010.
27.    Kaushik S. Dar L. Kaushik S. Yadav JP. Identification and characterization of new potent inhibitors of dengue virus NS5 proteinase from Andrographis paniculata supercritical extracts on in animal cell culture and in silico approaches. Journal of Ethnopharmacology. 2021;267:113541. doi: 10.1016/j.jep.2020.113541.
28.    Kaushik S. Kaushik S. Kumar R. Dar L. Yadav JP. In-vitro and in silico activity of Cyamopsis tetragonoloba (Gaur) L. supercritical extract against the dengue-2 virus. Virus Disease. 2020;31(4):470–78. doi: 10.1007/s13337-020-00624-9.
29.    Kaushik S. Kaushik S. Sharma V. Yadav JP. Antiviral and therapeutic uses of medicinal plants and their derivatives against dengue viruses. Pharmacognosy Reviews. 2018;12:177. doi: 10.4103/phrev.phrev_2_18.
30.    Sharma V. Kaushik S. Pandit P. Dhull D. Yadav JP. Kaushik S. Green synthesis of silver nanoparticles from medicinal plants and evaluation of their antiviral potential against chikungunya virus. Applied Microbiology and Biotechnology. 2019;103:881–91. doi: 10.1007/s00253-018-9488-1
31.    Kaushik S. Sharma V. Chhikara S. Yadav JP. Kaushik S. Anti-chikungunya activity of green synthesized silver nanoparticles using Carica papaya leaves in animal cell culture model. Asian Journal of Pharmaceutical and Clinical Research. 2019;12(6):170-4.
32.    Soniya K. Yadav S. Boora S. Kaushik S. Yadav JP. Kaushik S. The Cat Que Virus: a resurfacing orthobunyavirus could lead to epidemics. Virus Disease. 2021;32(4):635-41.
33.    Sharma Y, Kawatra A, Sharma V, Dhull D, Kaushik S, Yadav JP, Kaushik S. In-vitro and in-silico evaluation of the anti-chikungunya potential of Psidium guajava leaf extract and their synthesized silver nanoparticles. Virus Disease. 2021;32(2):260-5.
34.    Kumar S, Garg C, Kaushik S, Buttar HS, Garg M. Demystifying therapeutic potential of medicinal plants against chikungunya virus. Indian Journal of Pharmacology. 2021;53(5):403.
35.    Yashika Sharma, Sulochana Kaushik, Sanjit Boora, Pawan Kumar, Ajit Kumar, Jaya Parkash Yadav and Samander Kaushik  Antiviral Potential of Medicinal Plants for the COVID-19 Anti-Infective Agents 2022 DOI: 10.2174/2211352520666220425132933
36.    Kumar R, Nandwani S, Kaushik S. Green synthesized Allium cepa nanoparticles with enhanced antiprotozoal activities for E. gingivalis. Chemical Biology Letters. 2020 ; 27;7(4):247-50.
37.    Killedar SG, Kope KI, Sangle SB, Tamboli MS. Standardization and antimicrobial activity of watery fluid at floral base of Spathodea campanulata (Pal). Asian Journal of Pharmaceutical Analysis. 2011;1(1):19-21.
38.    Kumar K, Singh BK. Synthesis, characterization, and antimicrobial activity of some 4-thiazolidinone conjugatives. Asian Journal of Pharmaceutical Analysis. 2020 Dec 1;10(4).
39.    Purohit MC, Kandwal A, Purohit R, Semwal AR, Parveen S, Khajuria AK. Antimicrobial Activity of Synthesized Zinc Oxide Nanoparticles using Ajuga bracteosa Leaf Extract. Asian Journal of Pharmaceutical Analysis. 2021 Dec 1;11(4).
40.    Hemalatha M, Arirudran B, Thenmozhi A, Rao US. Antimicrobial effect of separate extract of acetone, ethyl acetate, methanol, and aqueous from leaf of Milkweed (Calotropis gigantea L.). Asian Journal of Pharmaceutical Research. 2011;1(4):102-7.
41.    Mohite SA, Shah RR, Patel NR. Antimicrobial Activity of Leaves extracts of Jatropha curcas. Asian Journal of Pharmaceutical Research. 2018;8(1):17-20.
42.    Kaushik S, Dar L, Kaushik S, Kumar R, Kumar D, Yadav JP. In vitro and in silico Anti-dengue activity of Supercritical extract of medicinal plants against Dengue serotype-2. Research Journal of Pharmacy and Technology. 2021 Nov 1;14(11):5895-902.
43.    Nitalikar MM, Nitalikar SM, Gunjotikar GA, Aragade PD. Study of antifungal effects of trachyspermum ammi (L.) Sprague. Research Journal of Pharmacy and Technology. 2010;3(1):76-8.
44.    Shrivastava K, Sahu S, Mishra SK, De K. In vitro antimicrobial activity and phytochemical screening of Syzygium aromaticum. Asian Journal of Research in Pharmaceutical Science. 2014;4(1):12-5.
45.    Mohite S, Shah R, Patel N. Antimicrobial activity of leaves extracts of Passiflora foetida. Asian Journal of Research in Pharmaceutical Sciences. 2018 Mar 21;8(1):17-20.
46.    Jeet K. Devi N. Narender T. Sunil T. Lalit S. Raneev T. Trachyspermum ammi (Ajwain): a comprehensive review. International Research Journal of Pharmacy. 2012;3(5):133-8.
47.    Seresht HR. Albadry BJ. Al-mosawi AK. Gholami O. Cheshomi H. The cytotoxic effects of thymol as the major component of Trachyspermum ammi on breast cancer (MCF-7) cells. Pharmaceutical Chemistry Journal. 2019;53(2):101-7. https://doi.org/10.1007/s11094-019-01961-w

Recomonded Articles:

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

1.3
2021CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags


Not Available