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Author(s): Bayan Shalhawi, Mohamad Sami Joha

Email(s): samihematology@gmail.com

DOI: 10.52711/0974-360X.2023.00673   

Address: Bayan Shalhawi, Mohamad Sami Joha*
Department of Biochemistry and Microbiology, Faculty of Pharmacy, Aleppo University, Syria.
*Corresponding Author

Published In:   Volume - 16,      Issue - 9,     Year - 2023


ABSTRACT:
Introduction: Many studies on type 2 diabetes had conflicting results about the prognostic importance of the ABO or Rhesus (Rh) D expression, and in this context, the other important types of Rh were never studied. Objective: The purpose of this study was to investigate whether ABO and Rh phenotype has an association with vascular complications in type 2 diabetes. Methods: 390 individuals were included in this study (194 were type 2 diabetic patients and 196 were healthy persons). 159 of diabetic patients were classified into two groups: group DC which included 98 diabetic patients with vascular complications, and group D which included 61 diabetic patients without vascular complications. A slide agglutination test was done to determine the ABO and Rh types. Results: While no difference was observed between the frequency of any ABO or Rh types between patients and healthy people, the frequency of A-type and each Rh+ type was higher in the DC group compared to the D group. In addition, the prevalence of the Rh DCceand Rh DcEphenotypes was higher in the DC group. Conclusion: Determining the phenotype of the Rhesus blood group may be a cheap and easy prognostic test for vascular complications development in type 2 diabetes.


Cite this article:
Bayan Shalhawi, Mohamad Sami Joha. Impact of ABO/Rhesus (D, C, c, E, e) blood type on development of vascular complications in type 2 diabetes. Research Journal of Pharmacy and Technology 2023; 16(9):4119-2. doi: 10.52711/0974-360X.2023.00673

Cite(Electronic):
Bayan Shalhawi, Mohamad Sami Joha. Impact of ABO/Rhesus (D, C, c, E, e) blood type on development of vascular complications in type 2 diabetes. Research Journal of Pharmacy and Technology 2023; 16(9):4119-2. doi: 10.52711/0974-360X.2023.00673   Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2023-16-9-17


REFERENCES:
1.    Reed J, et al. A review of current trends with type 2 diabetes epidemiology, aetiology, pathogenesis, treatments and future perspectives. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 2021 Aug 10;14:3567-602.doi: 10.2147/DMSO.S319895.
2.    Galicia-Garcia U,et al. Pathophysiology of type 2 diabetes mellitus. International Journal of Molecular Sciences. 2020 Aug 30;21(17):6275. doi: 10.3390/ijms21176275.
3.    Serbis A, et al. Diagnosis, treatmentand preventionof type 2 diabetes mellitus in children and adolescents. World Journal of Diabetes. 2021 Apr 15;12(4):344-365. doi: 10.4239/wjd.v12.i4.344.
4.    Jamal Alomar M, et al. Prediction model “T2DP” for the onset of Type 2 Diabetes Mellitus. Research Journal of Pharmacy and Technology. 202114;6:3325-32. doi: 10.52711/0974-360X.2021.00578.
5.    Rask-Madsen C, King G. Vascular complications of diabetes: Mechanisms of injury and protective factors. Cell Metabolism.2013 Jan 8;17(1):20-33. doi: 10.1016/j.cmet.2012.11.012.
6.    Ranjan S, Sharma PK. Association of Brain-Derived Neurotrophic factor (BDNF) gene SNP G196A with Type 2 Diabetes and Obesity: A Meta- Analysis. Research Journal of Pharmacy and Technology. 201710;12:4297-305. doi: 10.5958/0974-360X.2017.00787.9.
7.    Ibrahim R, et al. D Hypovitaminosis in Syrian Type 2 Diabetes Mellitus Patients: Lack of Relationship with Glycemic Control. Research Journal of Pharmacy and Technology. 201811;12:5319-26. doi: 10.5958/0974-360X.2018.00968.X.
8.    Geetha P, Shanmugasundaram P. A Prospective Observational Study on assessment of risk factor associated with diabetic retinopathy in patients diagnosed with type 2 Diabetes Mellitus in south Indian population. Research Journal of Pharmacy and Technology. 201912;2:595-99. doi: 10.5958/0974-360X.2019.00106.9.
9.    Mohammed SJ, Amin SS. The Distribution of ABO blood groups among type 2 Diabetes mellitus patients with or without Chronic Microvascular Complications. Research Journal of Pharmacy and Technology. 202215;8:3518-22. doi: 10.52711/0974-360X.2022.00590.
10.    Khudhair A, Al-Ganimi A. Evaluation of the Relationship between ABO Blood Groups, Rh Factor and Diabetes Mellitus Type 2. International Journal of Medical Research & Health Sciences.20187;11:110–14.
11.    Ebeye MO, et al. Association between ABO, Rhesus Blood Groups, and Type II Diabetes Mellitus among the Urhobos. Asian Hematology Research Journal. 2018 Jan 1;1:1–6. https://journalahrj.com/index.php/AHRJ/article/view/13175.
12.    Legese B, et al. Association of ABO and Rh Blood Group Phenotypes with Type 2 Diabetes Mellitus at FelegeHiwot Comprehensive Referral Hospital Bahir Dar, Northwest Ethiopia. International Journal of Chronic Diseases. 2020 Nov 5;2020: 2535843. doi: 10.1155/2020/2535843.
13.    Sharjeel S, et al. The Correlation Between Blood Group Type and Diabetes Mellitus Type II: A Case-Control Observational Study From Pakistan. Cureus. 2021 Nov 25;13(11):e19898. doi: 10.7759/cureus.19898.
14.    Aggarwal T, et al. Association of ABO and Rh blood groups with type 2 diabetes mellitus in Muzaffarnagar city. National Journal of Physiology, Pharmacy and Pharmacology. 2018 8;2: 167-170. doi: 10.5455/njppp.2018.8.0830324082017.
15.    Ghafar M, et al. Association of blood groups/Rh and diabetes mellitus in Karachi city, Pakistan. Brazilian Journal of Biology. 2022 Jan 7;84:e252952. doi: 10.1590/1519-6984.252952.
16.    Karagoz H, et al. The role of blood groups in the development of diabetes mellitus after gestational diabetes mellitus. Therapeutics and Clinical Risk Management. 2015 Oct 19;11:1613-7. doi: 10.2147/TCRM.S92294.
17.    Abegaz S. Human ABO Blood Groups and Their Associations with Different Diseases. BioMed Research International.2021 Jan 23;2021:6629060. doi: 10.1155/2021/6629060.
18.    Yu Q,et al. The role of ABO blood groups in Crohn’s disease and in monitoring response to infliximab treatment. Blood Transfusion.2016 Sep 14;5:460-4. doi: 10.2450/2016.0199-15.
19.    Franchini M, et al. The prognostic value of ABO blood group in cancer patients. Blood Transfusion.2016 Sep 14;5:434-40. doi: 10.2450/2015.0164-15.
20.    O’Connell JM, Manson SM. Understanding the economic costs of diabetes and prediabetes and what we may learn about reducing the health and economic burden of these conditions. Diabetes Care. 2019 Sep 42;9:1609-1611. doi: 10.2337/dci19-0017.
21.    Suraj B, et al. A Comparative Evaluation of Safety, Efficacy and Cost Effectiveness of Three add on Treatment Regimens in Type 2 Diabetics; not Controlled by Metformin Alone. Research Journal of Pharmacy and Technology. 2015 Jan 8;1:44-50.doi: 10.5958/0974-360X.2015.00009.8.
22.    Sriram S, et al. Cost Analysis of SGLT2 Inhibitors in patients with type 2 Diabetes in India. Research Journal of Pharmacy and Technology. 2020 13;12:5861-65. doi: 10.5958/0974-360X.2020.01021.5.
23.    Avijit M, Ashini S. A Review on Metformin: Clinical Significance and Side Effects. Research Journal of Pharmacy and Technology. 202114;11:6179-86. doi: 10.52711/0974-360X.2021.01070.
24.    Adi Jaya MK, et al. A Case-Control Study on Risk Factors affected Peripherals Neuropathic complication in Elderly with Type 2 Diabetes Mellitus. Research Journal of Pharmacy and Technology. 202114;8:4040-46. doi: 10.52711/0974-360X.2021.00700.
25.    Khalil K, Zrieki A. Factors associated with Glycemic control among Syrian patients with Type 2 Diabetes Mellitus. Research Journal of Pharmacy and Technology. 2022 15;4:1701-08. doi: 10.52711/0974-360X.2022.00285.
26.    Misevic G. ABO blood group system. Asia-Pacific Journal of Blood Types and Genes.20182;2:71–84. doi:10.46701/APJBG.2018022018113
27.    Avent N, Reid M. The Rh blood group system: a review. Blood.2000 Jan 15;95(2):375-87.
28.    Groot H, et al. Genetically determined ABO blood group and its associations with health and disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 2020 Mar 40;3:830-38. doi: 10.1161/ATVBAHA.119.313658.
29.    Langari S, et al. Coronary Heart Disease and ABO Blood Group in Diabetic Women: A Case-Control Study. Scientific Reports. 2019 May 15;9(1):7441. doi: 10.1038/s41598-019-43890-4.
30.    Caner T, et al. Mechanisms of ammonia and ammonium transport by rhesus-associated glycoproteins. American journal of physiology. Cell physiology. 2015 Dec 1;309(11):C747-58. doi: 10.1152/ajpcell.00085.2015.
31.    Liu XM, et al. Ammonia promotes endothelial cell survival via the heme oxygenase-1-mediated release of carbon monoxide. Free Radical Biology and Medicine.2017 Jan102:37-46. doi: 10.1016/j.freeradbiomed.2016.11.029.

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