Author(s):
Nangsih Sulastri Slamet, Fihrina Mohamad, Hartati, Muhammad Isrul
Email(s):
nangsihslamet@poltekkesgorontalo.ac.id
DOI:
10.52711/0974-360X.2024.00731 
Address:
Nangsih Sulastri Slamet1*, Fihrina Mohamad2, Hartati2, Muhammad Isrul3
1Department of Chemical Engineering, Politeknik Negeri Ujung Pandang, South Sulawesi Province, Indonesia.
2Department of Pharmacy, Poltekkes Kemenkes Gorontalo, Gorontalo Province, Indonesia.
3Pharmacy Departement, Science and Technology Faculty, Mandala Waluya University.
*Corresponding Author
Published In:
Volume - 17,
Issue - 10,
Year - 2024
ABSTRACT:
The Covid-19 virus continues to spread in different countries, including Indonesia, which has not shown a substantial decline until the present day. This has prompted the government and society to seek various methods to survive in order to maintain a prosperous life. It is recommended to consume nutritious food, beverages, supplements, or medications that contain immunostimulant substances to strengthen immunity and prevent the spread of the Covid-19 virus. Various medicinal plants worldwide, including those in Indonesia, have been scientifically proven to contain secondary metabolites such as alkaloids, flavonoids, saponins, and tannins, which exhibit immunostimulant activities. This descriptive research combines qualitative and quantitative methods, including surveys, interviews, and phytochemical screening. Its objective is to analyze the results of ethnopharmaceutical and scientification of immunostimulant medicinal plants used by the Suwawa tribe in Gorontalo Province and the Muna tribe in Southeast Sulawesi during the Covid-19 pandemic. This study involved15 informants, which divided 9 participants from the Suwawa tribe and 4 from the Muna tribe. Based on interviews and calculations of the Informant Consensus Factor (ICF) and Use Value (UV), the most frequently used plant was identified and processed into crude drugs.The phytochemical screening results revealed that the plants contained group compounds.
Cite this article:
Nangsih Sulastri Slamet, Fihrina Mohamad, Hartati, Muhammad Isrul. Ethnopharmacy and Scientification of Immunostimulants plants used by The Suwawa Tribe in Gorontalo Province and The Muna Tribe in Southeast Sulawesi Province during The Covid-19 Pandemic. Research Journal of Pharmacy and Technology. 2024; 17(10):4745-0. doi: 10.52711/0974-360X.2024.00731
Cite(Electronic):
Nangsih Sulastri Slamet, Fihrina Mohamad, Hartati, Muhammad Isrul. Ethnopharmacy and Scientification of Immunostimulants plants used by The Suwawa Tribe in Gorontalo Province and The Muna Tribe in Southeast Sulawesi Province during The Covid-19 Pandemic. Research Journal of Pharmacy and Technology. 2024; 17(10):4745-0. doi: 10.52711/0974-360X.2024.00731 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2024-17-10-16
REFERENCES:
1. Olivia S, Gibson J, Nasrudin RA. Indonesia in the Time of Covid-19. Bulletin of Indonesian Economic Studies. 2020; May; 56(2): 143-74.
2. Ahmad S, Shoaib A, Ali S, Alam S, Alam N, Ali M, Mujtaba A, Ahmad A, Ansari S, Ali D. Epidemiology, risk, myths, pharmacotherapeutic management and socio-economic burden due to novel covid-19: A recent update. Research Journal of Pharmacy and Technology. 2021; 14(4): 2308-15.
3. Menon S, Bhagat V. A Review Study on the impact of COVID-19 on Mental Health in the workplace and on working people. Research Journal of Pharmacy and Technology. 2021; 14(12): 6725-31.
4. Benil PB, Roy V, Rajagopal R, Alfarhan A. Role of nutraceuticals as immunomodulators to combat viruses. InViral Infections and Antiviral Therapies. 2023; Jan 1 (653-689). Academic Press.
5. Babich O, Sukhikh S, Prosekov A, Asyakina L, Ivanova S. Medicinal plants to strengthen immunity during a pandemic. Pharmaceuticals. 2020; Oct 15; 13(10): 313.
6. Kumar RB, Suryanarayana B. Ethnomedicinal recipes for Urinary and Kidney ailments from Tribals of Sriharikota Island, Andhra Pradesh. Research Journal of Pharmacy and Technology. 2015; 8(4): 468-75.
7. Behera S, Mahalik G. A Survey on the Ethnomedicinal plants and Antimicrobial activity of Tridax procumbens L. Research Journal of Pharmacy and Technology. 2022; 15(1): 219-23.
8. Maroyi A. A synthesis and review of ethnomedicinal uses, phytochemistry and biological activities of Paropsiabrazzeanabaill.(passifloraceae). Research Journal of Pharmacy and Technology. 2022; 15(11): 5331-6.
9. Gautam DN. Ethnomedicinal, Toxicity and Pharmacological study of Abrus precatorious: A Critical Review. Research Journal of Pharmacy and Technology. 2017; 10(10): 3621-7.
10. Saleh A, Yuliastri WO, Isrul M, Pusmarani J, Juliansyah R, Dewi C. Ethnomedicinal Study of Medicinal Plants used against Infectious Disease by Muna Tribe of South-East Sulawesi, Indonesia. Research Journal of Pharmacy and Technology. 2020;13(4):1829-34.
11. Maroyi A. A synthesis and review of ethnomedicinal uses, phytochemistry and biological activities of Paropsiabrazzeanabaill. (passifloraceae). Research Journal of Pharmacy and Technology. 2022; 15(11): 5331-6.
12. Shiyan S, Arifin A, Amriani A, Pratiwi G. Immunostimulatory activity of ethanol extract from Calotropis gigantea L. flower in rats against Salmonella typhimurium infection. Res J Pharm Technol. 2020; Nov 13; 13(11): 5244-50.
13. Parida R, Nayak S. Anti-proliferative activity of in vitro Zingiberaceae essential oil against Human cervical cancer (HeLa) cell line. Research Journal of Pharmacy and Technology. 2022; 15(1): 325-8.
14. Hidayah I, Indradadi RB. Review artikel aktivitasimuno modulator be berapatanamandarisuku Zingiberaceae. Jurnal Kesehatan Bakti Tunas Husada: JurnalIlmu-ilmuKeperawatan, Analis Kesehatan dan Farmasi. 2020; Sep 28; 20(2): 181-93.
15. Ahmadifar E, Sheikhzadeh N, Roshanaei K, Dargahi N, Faggio C. Can dietary ginger (Zingiber officinale) alter biochemical and immunological parameters and gene expression related to growth, immunity and antioxidant system in zebrafish (Danio rerio). Aquaculture. 2019; May 30; 507: 341-8.
16. Chandrasekaran CV, Sundarajan K, Edwin JR, Gururaja GM, Mundkinajeddu D, Agarwal A. Immune-stimulatory and anti-inflammatory activities of Curcuma longa extract and its polysaccharide fraction. Pharmacognosy Research. 2013; Apr; 5(2): 71.
17. Kumolosasi E, Ibrahim SN, Shukri SM, Ahmad W. Immunostimulant activity of standardised extracts of Mangifera indica leaf and Curcuma domestica rhizome in mice. Tropical Journal of Pharmaceutical Research. 2018; 17(1): 77-84.
18. Mathayan M, Suresh A, Balamurugan R, Jayaraman S. Immune Stimulation effects of Pongamia pinnata extracts, an In vitro Analysis. Research Journal of Pharmacy and Technology. 2020; 13(1): 308-12.
19. Utami YP, Ardi MA. Antimalarial Activity of Ethanol Extract of Sampare Leaves (Glochidionsp var. Biak) Against Plasmodium falciparum In Vitro. Indonesian Journal of Pharmaceutical Science and Technology. 2023; Feb 28; 10(1): 10-8.