Author(s):
Deepak Kumar, Sukender Kumar, Bhoj Raj, Ramchander Khatri, Amit Lather, Tanuj Hooda
Email(s):
tanujhooda2010@gmail.com
DOI:
10.52711/0974-360X.2024.00722 
Address:
Deepak Kumar1, Sukender Kumar2, Bhoj Raj2, Ramchander Khatri3, Amit Lather4, Tanuj Hooda4*
1Jaipur College of Pharmacy, Jaipur-302022.
2Department of Pharmaceutical Sciences, Choudhary Bansilal University, Bhiwani-127021.
3Delhi Pharmaceutical Sciences and Research University, New Delhi, Delhi-110017.
4MM College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullan, Ambala-133207.
*Corresponding Author
Published In:
Volume - 17,
Issue - 10,
Year - 2024
ABSTRACT:
Introduction: The leaves of Saraca asoca (the Ashoka tree), a member of Caesalpinioideae family, have been used widely in Traditional medicines; however, their wound healing ability in diabetic condition is not investigated yet. The aim of present study was to investigate the anti-diabetic and wound healing potential of Saraca asoca leaves extract in various streptozocin induces diabetic animal models. Methods: Antidiabetics activity was evaluated in streptozocin induced rat models and wound healing potential was determined using excision and incision wound models. Results: The aqueous and ethanolic extracts induced hypoglycemia and improved glucose tolerance in normal rats, despite the presence of counter-regulatory mechanisms aimed at preventing a decrease in blood glucose levels. This suggests that the hypoglycemic action of the aqueous and ethanolic extracts may be attributed to extra-pancreatic processes or by stimulating the remaining cells to produce more insulin. Conclusion: The present study suggests that the extracts of Saraca asoca leave have significant anti-diabetic and wound healing potential.
Cite this article:
Deepak Kumar, Sukender Kumar, Bhoj Raj, Ramchander Khatri, Amit Lather, Tanuj Hooda. Anti-diabetic and Wound healing potential of plant Saraca asoca leaves in various Diabetic animal models. Research Journal of Pharmacy and Technology. 2024; 17(10):4685-3. doi: 10.52711/0974-360X.2024.00722
Cite(Electronic):
Deepak Kumar, Sukender Kumar, Bhoj Raj, Ramchander Khatri, Amit Lather, Tanuj Hooda. Anti-diabetic and Wound healing potential of plant Saraca asoca leaves in various Diabetic animal models. Research Journal of Pharmacy and Technology. 2024; 17(10):4685-3. doi: 10.52711/0974-360X.2024.00722 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2024-17-10-7
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