Author(s): Palshikar Gautam, Soni Gauravkumar, Otari Kishor, Shanmugapandiyan Pitchaimuthu


DOI: 10.52711/0974-360X.2024.00207   

Address: Palshikar Gautam1,2*, Soni Gauravkumar2, Otari Kishor2, Shanmugapandiyan Pitchaimuthu3
1Department of Pharmacy, Centre for Research and Development (CRD), PRIST Deemed To Be University, Thanjavur 613403, Tamil Nadu, India.
2Navsahyadri Education Society’s, Navsahyadri Institute of Pharmacy, Naigaon, Pune - 412213, Maharashtra, India.
3Sathyabama Institute of Science and Technology, Chennai - 600 119. Tamilnadu, India.
*Corresponding Author

Published In:   Volume - 17,      Issue - 3,     Year - 2024

Now a day, more number of individuals from all over the world get suffered from diabetes which is an endocrine and metabolic disorder. Herbal medicines are used for treatment of such a chronic diseases from hundreds of years and are continuously rising in todays era due to less adverse effects, treats root cause and low cost. Jamun acts as a promising herb due to its proven hypoglycemic action and ability to prevent many adverse conditions due to it. Stigmasterol, an active phytoconstituent from Jamun has been credited for its antidiabetic potential. Seasonal fluctuations have impact on availability of active components in herbs which also influence its therapeutic efficacy. For getting yield with more potency, the harvesting should be done properly at accurate altitude, month and duration. Research objective is to find out changes in contents of medicinal plant Jamun leaves for antidiabetic potential. Plant sample used in different seasons, time and places, identification and analysis was performed. Macroscopy, microscopy, proximate phytochemistry, extraction yield and estimation of the yield of stigmasterol. Morphological, microscopical and extractive values appears fluctuations Maximum levels of ethanol extract with higher concentration of stigmasterol were obtained in August month.

Cite this article:
Palshikar Gautam, Soni Gauravkumar, Otari Kishor, Shanmugapandiyan Pitchaimuthu. Fluctuations due to Altitude, Season and Time on Potency of Stigmasterol content of Jamun. Research Journal of Pharmacy and Technology. 2024; 17(3):1320-3. doi: 10.52711/0974-360X.2024.00207

Palshikar Gautam, Soni Gauravkumar, Otari Kishor, Shanmugapandiyan Pitchaimuthu. Fluctuations due to Altitude, Season and Time on Potency of Stigmasterol content of Jamun. Research Journal of Pharmacy and Technology. 2024; 17(3):1320-3. doi: 10.52711/0974-360X.2024.00207   Available on:

1.    Dash S. P. Dixit S. and Sahoo S. Phytochemical and Biochemical Characterizations from Leaf Extracts from Azadirachta indica: An Important Medicinal Plant. Biochemistry and Analytical Biochemistry. 2017; 6(2): 1-4. DOI: https:/
2.    Chen S. L. Yu H.  Luo H.M. Wu Q. Li C F. and Steinmetz A. Conservation and sustainable use of medicinal plants: problems, progress, and prospects. Chinese Medicine. 2016; 11 (37): 1-6. DOI: https:// /10.1186/s13020-016-0108-7.
3.    Yuan H. Ma Q. Ye L. Piao G. The Traditional Medicine and Modern Medicine from Natural Products Molecules. Molecules.  2016; 21 (559):1-18. DOI:
4.    Sen S. and Chakraborty R. Revival, modernization and integration of Indian traditional herbal medicine in clinical practice: Importance, challenges and future, Journal of Traditional and Complementary Medicine. 2017; 7 (2): 234 -244. DOI: https:// 253A+10.1016%252Fj.jtcme.2016.05.006.
5.    Ekor M. The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety. Frontiers in Pharmacology. 2013; 4 (177): 1-10. DOI: https://
6.    Chaudhury A. Duvoor C. Reddy Dendi VS.  Kraleti S. Chada A. Ravilla R. Marco A. Shekhawat, NS. Montales MT. Kuriakose K. Sasapu A. Beebe A. Patil N. Musham C. K.  Lohani GP. Mirza W. Clinical Review of Antidiabetic Drugs: Implications for Type 2 Diabetes Mellitus Management. Frontiers in Endocrinology. 2017; 8 (6): 1- 12. DOI:
7.    Kooti W. Farokhipour M. Asadzadeh Z. Larky D A. and Samani M.A. The role of medicinal plants in the treatment of diabetes. Electron Physician.   2016; 8 (1): 1832–1842. DOI: https:/doi%253A+10.19082%252F1832.
8.    Karachaliou F. Simatos G. and Simatou A. The Challenges in the Development of Diabetes Prevention and Care Models in Low-Income Settings. Frontiers in Endocrinology. 2020; 11 (518): 1-9. DOI: 10.3389/fendo.2020.00518.
9.    Cho N. H.  Shaw J. E.  Karuranga S. Huang Y. Fernandes J D R.  Ohlrogge A W. Malanda B. Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045. Diabetes Research Clinical Practice. 2018; 138: 271-281. DOI: https:// / 10.1016/j.diabres.2018.02.023.
10.    Oyebode O. Kandala N B. Chilton P J. Lilford R J. Use of traditional medicine in middle-income countries: a WHO-SAGE study. Health Policy Plan. 2016; 31 (8): 984 -991. DOI: https://
11.    Anand U. Herrera N J. Altemimi A. Lakhssassi N. A Comprehensive Review on Medicinal Plants as Antimicrobial Therapeutics: Potential Avenues of Biocompatible Drug Discovery. Metabolites. 2019; 9 (11): 258. DOI: https:/doi%253A+10.3390%252Fmetabo9110258.
12.    Tran N. Pham B. Le L. Bioactive Compounds in Anti-Diabetic Plants: From Herbal Medicine to Modern Drug Discovery. Biology. 2020; 9 (9): 252. DOI: https:/ 9090252.
13.    Thomas A. Kanakdhar A. Shirsat A. Deshkar S. Kothapalli L. A High Performance Thin Layer Chromatographic Method Using a Design of Experiment Approach. Turkish Journal of Pharmaceutical Sciences. 2020; 17 (2): 148-158. DOI: 10.4274/tjps.galenos.2018.80958.

Recomonded Articles:

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

56th percentile
Powered by  Scopus

SCImago Journal & Country Rank

Recent Articles


Not Available