Author(s): Candra Irawan, Imas Solihat, Sellafiana Sunu Praptiwi, Miska Mufidah, Elisa Listianti, Bulan Safitri


DOI: 10.52711/0974-360X.2024.00343   

Address: Candra Irawan, Imas Solihat*, Sellafiana Sunu Praptiwi, Miska Mufidah, Elisa Listianti, Bulan Safitri
Department of Food Nanotechnology, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, Indonesia.
*Corresponding Author

Published In:   Volume - 17,      Issue - 5,     Year - 2024

Temu Hitam (Curcuma aeruginosa Roxb) is recognized as one of the plants that has the potential to be utilized in the practice of traditional medicine. The selection of the extraction method is an essential initial step in the process of chemical component purification. In this particular investigation, the extraction process was carried out utilizing a variety of techniques, including hot maceration, cold maceration, and ultrasound-assisted extraction (UAE), in order to investigate the anti-inflammatory, antioxidant, and cytotoxicity capabilities of the subject material. The percent yield from the UAE method showed the highest amount of 51.94%, and the IC50 values from the cold method, hot method, and UAE using the FRAP method were 4.65, 6.22, and 5.57 ppm, respectively. The extract using the UAE method has higher cytotoxicity to Artemia salina Leach larvae. In addition, UAE showed better anti-inflammatory activity with an IC50 value of 2.96 ppm.

Cite this article:
Candra Irawan, Imas Solihat, Sellafiana Sunu Praptiwi, Miska Mufidah, Elisa Listianti, Bulan Safitri. Effect of Extraction Method on Antioxidant Activity, Anti-inflammation and Cytotoxicity of Curcuma aeruginosa Roxb. Rhizome. Research Journal of Pharmacy and Technology. 2024; 17(5):2180-4. doi: 10.52711/0974-360X.2024.00343

Candra Irawan, Imas Solihat, Sellafiana Sunu Praptiwi, Miska Mufidah, Elisa Listianti, Bulan Safitri. Effect of Extraction Method on Antioxidant Activity, Anti-inflammation and Cytotoxicity of Curcuma aeruginosa Roxb. Rhizome. Research Journal of Pharmacy and Technology. 2024; 17(5):2180-4. doi: 10.52711/0974-360X.2024.00343   Available on:

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