Author(s):
Bharathi Arigela, Mani Sai Raja Sri Nitish Jillella, Achanti Suneetha
Email(s):
bharathi.arigela004@gmail.com
DOI:
10.52711/0974-360X.2025.00454 
Address:
Bharathi Arigela1*, Mani Sai Raja Sri Nitish Jillella2, Achanti Suneetha3
1Professor, Department of Pharmaceutics and Biotechnology, KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh, India.
2M.Pharm Scholar, Department of Pharmaceutics and Biotechnology, KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh, India.
3Professor and Principal, KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh.
*Corresponding Author
Published In:
Volume - 18,
Issue - 7,
Year - 2025
ABSTRACT:
The Mission of this research is to formulate and enhance the release of Diclofenac sodium utilising Tamarind Kernel Gum (TKG) as natural polymer. The study investigated the potential of TKG by comparing with Hydroxy Propyl Methyl Cellulose (HPMC) and Sodium Carboxy Methyl Cellulose (Na CMC). Nine formulations were designed, three of which incorporated TKG, HPMC and Sodium CMC. Wet Granulation Technique was employed for the formulation of Diclofenac sodium matrix tablets and evaluation tests were performed to check the performance of tablets. The study sought to examine the effect of various matrix formers on the release retardant property The formulations, comprised of tamarind kernel gum, had a longer duration release profile, as demonstrated by invitro studies and kinetic analysis In conclusion, the use of natural polymer in diclofenac sodium tablet formulation offers the promise of sustained release medications.
Cite this article:
Bharathi Arigela, Mani Sai Raja Sri Nitish Jillella, Achanti Suneetha. Formulation and Evaluation of Diclofenac Sodium Matrix Tablets using Tamarind Kernel Gum. Research Journal of Pharmacy and Technology. 2025;18(7):3159-3. doi: 10.52711/0974-360X.2025.00454
Cite(Electronic):
Bharathi Arigela, Mani Sai Raja Sri Nitish Jillella, Achanti Suneetha. Formulation and Evaluation of Diclofenac Sodium Matrix Tablets using Tamarind Kernel Gum. Research Journal of Pharmacy and Technology. 2025;18(7):3159-3. doi: 10.52711/0974-360X.2025.00454 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2025-18-7-34
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