Author(s):
Mahalakshmi V., Jyothirmai K., Sudhakara Reddy, Atla Srinivas Rao, K.T. Sunil Kumar, Veerakumari M.
Email(s):
vadladhi.mahalakshmi@gmail.com , jyothirmaik@vdc.edu.in , sudhakarareddyomr@gmail.com , drasr@svcp.edu.in , sunil@svcp.edu.in , veerakumari.m@vdc.edu.inph
DOI:
10.52711/0974-360X.2025.00455 
Address:
Mahalakshmi V.1, Jyothirmai K.2, Sudhakara Reddy3, Atla Srinivas Rao4, K.T. Sunil Kumar5, Veerakumari M.6
1Former Postgraduate, Dept. of Oral Medicine and Radiology, Vishnu Dental College, Bhimavaram.
2Professor and HOD, Dept. of Oral Medicine and Radiology, Vishnu Dental College. Bhimavaram.
3Professor, Dept. of Oral Medicine and Radiology, Vishnu Dental College, Bhimavaram.
4Professor and HOD, Dept. of Pharmacology, Sri Vishnu College of Pharmacy, Bhimavaram.
5Associate Professor, Dept of Pharmacology, Sri Vishnu College of Pharmacy, Bhimavaram.
6Reader, Dept. of Oral Medicine and Radiology, Vishnu Dental College, Bhimavaram.
*Corresponding Author
Published In:
Volume - 18,
Issue - 7,
Year - 2025
ABSTRACT:
Denture stomatitis is a form of oral candidiasis and is a very common inflammatory process on palatal and gingival mucosa which is in direct contact with the denture base. Punica granatum (Pomegranate) is the plant with medicinal and nutritional benefit for which it is used in medicine for treating various diseases. Objectives: To evaluate the effectiveness of Punica granatum peel extract clinically and mycologically in patients with denture stomatitis and to compare clinically and mycologically, the effectiveness of Punica granatum with that of Miconazole. Methodology: After obtaining informed consent a total of 50 patients diagnosed with denture stomatitis were selected. Each group consisted of 25 patients, and they were split into two at random. Group A received Punica granatum gel and Group B received Miconazole Daktarin® gel oral. Results: The results revealed significant difference in the erythematous area, number of petechiae and colony forming units within the study and control groups. Conclusion: Punica granatum can be used as an alternative topical antifungal agent.
Cite this article:
Mahalakshmi V., Jyothirmai K., Sudhakara Reddy, Atla Srinivas Rao, K.T. Sunil Kumar, Veerakumari M.. Effectiveness of Punica granatum Peel Extract as an Antifungal agent in the patients with Denture Stomatitis - A Randomized Double Blinded Clinical Trial. Research Journal of Pharmacy and Technology. 2025;18(7):3164-8. doi: 10.52711/0974-360X.2025.00455
Cite(Electronic):
Mahalakshmi V., Jyothirmai K., Sudhakara Reddy, Atla Srinivas Rao, K.T. Sunil Kumar, Veerakumari M.. Effectiveness of Punica granatum Peel Extract as an Antifungal agent in the patients with Denture Stomatitis - A Randomized Double Blinded Clinical Trial. Research Journal of Pharmacy and Technology. 2025;18(7):3164-8. doi: 10.52711/0974-360X.2025.00455 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2025-18-7-35
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