Author(s):
Shyam Baboo Prasad, Akshada Murkute, Prasad GP, Arun M Gurav, Mangal AK, Shidddamallayya, N. Srikanth, Rabinarayan Acharya
Email(s):
shyamprasad@ccras.nic.in
DOI:
10.52711/0974-360X.2025.00480 
Address:
Shyam Baboo Prasad1,2*, Akshada Murkute1,3, Prasad GP4, Arun M Gurav1, Mangal AK2, Shidddamallayya5, N. Srikanth5, Rabinarayan Acharya5
1Regional Ayurveda Research Institute, Pune, Maharastra (India)
2Central Ayurveda Research Institute, Kolkata, West Bengal (India)
3CES'S Indira College of Pharmacy, Pune, Maharastra (India)
4National Institute of Indian Medical Heritage, Hyderabad (Telangana), India
5Central Council for Research in Ayurvedic Sciences, New Delhi (India)
*Corresponding Author
Published In:
Volume - 18,
Issue - 7,
Year - 2025
ABSTRACT:
Cryptolepis dubia previously known as Cryptolepis buchnani is used in traditional system of medicine for treatment of ailments specially bone and skin disorders. The stem of this plant having potential therapeutic activity and used by tribals, but the identification and authentication data is not available in scientific manners. To consider this an attempt has been taken to develop pharmacognostic, physicochemical and HPTLC standards. The quality standard data for Cryptolepis dubia is developed for the first time which contribute significant role in identity, authentication, evaluation of quality, and detection of adulteration.
Cite this article:
Shyam Baboo Prasad, Akshada Murkute, Prasad GP, Arun M Gurav, Mangal AK, Shidddamallayya, N. Srikanth, Rabinarayan Acharya. Quality Aspects of Stem of Cryptolepis dubia (Burm. F.) M. R. Almeida on the basis of Pharmacognostic Physicochemical and Chromatographic Evaluation. Research Journal of Pharmacy and Technology. 2025;18(7):3324-9. doi: 10.52711/0974-360X.2025.00480
Cite(Electronic):
Shyam Baboo Prasad, Akshada Murkute, Prasad GP, Arun M Gurav, Mangal AK, Shidddamallayya, N. Srikanth, Rabinarayan Acharya. Quality Aspects of Stem of Cryptolepis dubia (Burm. F.) M. R. Almeida on the basis of Pharmacognostic Physicochemical and Chromatographic Evaluation. Research Journal of Pharmacy and Technology. 2025;18(7):3324-9. doi: 10.52711/0974-360X.2025.00480 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2025-18-7-60
REFERENCES:
1. Laupattarakasem P, Houghton PJ, Hoult JRS, Itharat A. An evaluation of the activity related to inflammation of four plants used in Thailand to treat arthritis. J Ethnopharmacol. 2003; 85: 207-15.
2. Sharma D, Sahu A, Mujeeb M, Bharti A, Sharma A, Tripathi RK, Ashraf K. et al., Development of pharmacognostical profile of Cryptolepis buchanani Roem and Schult. Int J Pharm Pharm Sci. 2012; 4: 615-18.
3. Tayung K, Saikia, N. Cryptolepis buchanani-A less-known medicinal plant used in bone fracture. Indian J Tradit Knowl. 2003; 2:371-74.
4. Singh V. 2017. Medicinal plants and bone healing. Natl J of Maxillofac Surg. 2017; 8: 4.
5. Ignacimuthu S, Ayyanar M. Ethnobotanical investigations among tribes in Madurai district of Tamil Nadu (India). J Ethnobiol Ethnomed. 2006; 2:1-7.
7. Jagtap SD, Deokule SS, Pawar PK, Kuvalekar AA, Harsulkar AM. Antimicrobial activity of some crude herbal drugs used for skin diseases by Pawra tribes of Nandurbar district. Indian J Nat Prod Resour. 2010; 1: 216-20.
8. Ramya S. Ethnomedicinal perspectives of botanicals used by Malayali Tribes in Vattal Hills of Dharmapuri (TN), India. Ethnobot Leafl. 2008; 2008(1): 139.
9. Mangal AK, Tomer R, Jindal H, Prasad SB, Singh H, Sharma BS, Srikanth N, Dhiman KS. Development and standardisation of Laghu Sudarshan Churna–An Ayurvedic polyherbal formulation. Indian Journal of Traditional Knowledge. 2022; 21(1) 106-112.
10. Kumari, T. J., Pratap, G. P., Prasad, S. B., Murthy, P., and Prasad, G. P. Standardization of balamula churna (Sida cordifolia L. root powder). International Journal of Current Pharmaceutical Research. 2019: 27-30.
11. Mangal AK, Tomer R, Jindal H, Dahiya J, Prasad SB, Singh H, Sharma BS, Srikanth N. Development of Quality Control Parameters for Classical Ayurvedic Formulation: Vyoshadi Churna. Journal of Ayurveda. 2023 Jan 1; 17(1): 38-44.
12. Mangal AK, Tomer R, Jindal H, Prasad SB, Sharma H, Sharma BS, Srikanth N, Dhiman KS. Development and standardization of Chaturbhadra Kvath Churna: An ayurvedic formulation. Journal of Drug Research in Ayurvedic Sciences. 2019; 4(4): 192-8.
13. Sharma M, Prasad SB. Standardisation of Guazuma tomentosa leaf. Int J Pharmacogn Phytochem Res. 2014; 6(4):1010-4.
14. Nirawane RB, Prasad SB, Kumar S, Gurav AM, Rao G, Prasad GP, Mangal AK. Pharmacognostic Evaluation of Root of Albizia lebbeck (Linn.) Benth. International Journal of Pharmacognosy and Phytochemical Research. 2018; 10(5): 229-34.
15. Prasad SB, Sharma A. Standardisation of convolvulus pluricaulis choisy herbs collected from Jalandhar, Punjab. Int. J. Pharmacogn. Phytochem. Res. 2016; 8: 1412-6.
16. Prasad SB, Gurav AM, Prasad GP. Pharmacognostic and Preliminary Phytochemical Evaluation of Leaf of Syzygium Cumini (L.) Skeels. International Journal of Ayurvedic Medicine. 12(3): 684-8.
17. Shyam Baboo Prasad, Snehal Gaikwad, Shiddamallayya Nagayya, Arun M. Gurav, Goli P Prasad, Anupam K. Mangal, Venkateshwarlu Bandi, Narayanam Srikanth. Pharmacognostic and Preliminary Phytochemical Evaluation of root of Coptis teeta Wall. Research Journal of Pharmacy and Technology. 2024; 17(5): 1933-7.
18. Shyam Baboo Prasad Snehal Gaikwad Arun M. Gurav Anupam K. Mangal Shiddamallayya Nagayya Venkateshwarlu Bandi Narayanam Srikanth Rabinarayan Acharya. Pharmacognostic and Phytochemical Evaluation of Staminate Flower of Cocos nucifera L. Journal of Natural Remedies. 2024; 24 (5); 1117-1124.
19. Pratap GP, Husain MK, Prasad SB, Gurav AM, Alam M, Prasad GP, Munshi YI. Phyto-Pharmacognostical Standardization of Three Morpho-Variants of Cissus quadrangularis L. Pharmacognosy Research. 2024; 16(3).
20. Gandhi Y, Kumar V, Singh G, Prasad SB, Mishra SK, Soni H, Rawat H, Singh S, Charde V, Gupta A, Dhanjal DS. Chemoprofiling and medicinal potential of underutilized leaves of Cyperus scariosus. Scientific Reports. 2024; 14(1): 7263.
21. Gandhi MY, Prasad SB, Kumar V, Soni H, Rawat H, Mishra SK, Grewal J, Singh S, Charde V, Gupta A, Jha SK. Quantification of Phytochemicals and Metal Ions as well as the Determination of Volatile Compounds, Antioxidant, Antimicrobial and Antacid Activities of the Mimosa pudica L. Leaf: Exploration of Neglected and Under‐Utilized Part. Chemistry and Biodiversity. 2023; 20(10): e202301049.
22. Gandhi Y, Rawat H, Kumar V, Thakur A, Mishra SK, Charde V, Soni H, Singh G, Tandon S, Kumar R, Shakya SK. Identification of two kinds of Colchicum corms by DNA barcoding, physicochemical, chromatographic and chemometric analyses along with pharmacognostic parameters. Microchemical Journal. 2023; 195: 109399.
23. Dahiya J, Mangal AK, Bolleddu R, Kumar D, Abdullah S, Prasad SB, Dutta S, Mall S, Hazra K, Babu G. HPTLC Based Marker and Fingerprint Analysis Coupled with Multivariate Analysis of Different Parts of Cyanthillium cinereum from Different Geographical Locations. Chromatographia. 2024; Nov 21: 1-2.
24. Sharma H, Mishra SK, Khan R, Prasad SB, Narasimhaji CV, Srikanth N, Acharya R. A validated phytochemical marker based HPTLC method for the segregation of Bauhinia vahlii Wight and Arn. from geologically different samples of Indian zones. JPC–Journal of Planar Chromatography–Modern TLC. 2024; 37(4): 331-43.