Author(s):
Ashlesha Arun Wakchaure, Manoj Ramesh Kumbhare, G.B. Jadhav, Sonali Ramrao Gawali, K.N. Mundlod
Email(s):
wakchaureashlesha01@gmail.com
DOI:
10.52711/0974-360X.2025.00581 
Address:
Ashlesha Arun Wakchaure1, Manoj Ramesh Kumbhare2, G.B. Jadhav3, Sonali Ramrao Gawali3, K.N. Mundlod3
1Department of Pharmaceutical Chemistry, S.M.B.T. College of Pharmacy, Nashik, Savitribai Phule Pune University, Maharashtra, India.
2Professor, Department of Pharmaceutical Chemistry, S.M.B.T. College of Pharmacy, Nashik, Savitribai Phule Pune University, Maharashtra, India.
3MVP Samaj’s College of Pharmacy, Nashik, Savitribai Phule Pune University, Maharashtra, India.
*Corresponding Author
Published In:
Volume - 18,
Issue - 9,
Year - 2025
ABSTRACT:
The objective of study to presented detail pharmacognostic profile, phytochemical characterization and in vitro antioxidant activity of Cyphostemma auriculatum (Roxb.) with enormous therapeutic activities belongs to the family Vitaceae. The Leaves of plant were collected and the pharmacognostic nature and powder microscopy were performed.The Leaves are digitate, 5-foliolate. Petioles 4-12 cm long, terminal leaflet obovate to rhomboid or elliptic at base, serrate at margin, acute to short-acuminate at apex, 9-14 x 4.5-9.5 cm, petiolules 1-2 cm long. Microscopical identification of transverse section of the leaf has presence of covering trichomes and anomocytic stomata in the lower epidermis of the leaf. Upper epidermis cells are polygonal. Powder characteristic of leaves shows the presence of stomata, covering trichomes, annular vessels, acicular crystals of calcium oxalate in bundles and scattered form. The shade dried crude plant drug powder was tested for ash value, extractive values and loss on drying. The crude drug extracted with Petroleum ether and ethanol. The preliminary phytochemical test shows presence of flavonoids, alkaloids, tannins, carbohydrates, glycoside, triterpenoids, proteins, steroids. The petroleum ether and ethanolic extract of the leaves of Cyphostemma auriculatum (Roxb.) were tested for Total phenolic content and antioxidant activity using 1,1-diphenyl, 2-picryl hydrazyl (DPPH) free radical scavenging activity. In ethanolic extract showed the most significant activity of DPPH free radical scavenging activity than other extract. The results of the study can serve valuable source of information and provides suitable standard for identification of this plant material.
Cite this article:
Ashlesha Arun Wakchaure, Manoj Ramesh Kumbhare, G.B. Jadhav, Sonali Ramrao Gawali, K.N. Mundlod. Pharmacognostic Standardization and Correlation of Total Phenolic Content with Antioxidant Activity in Cyphostemma auriculatum Roxb. Research Journal of Pharmacy and Technology. 2025;18(9):4047-4. doi: 10.52711/0974-360X.2025.00581
Cite(Electronic):
Ashlesha Arun Wakchaure, Manoj Ramesh Kumbhare, G.B. Jadhav, Sonali Ramrao Gawali, K.N. Mundlod. Pharmacognostic Standardization and Correlation of Total Phenolic Content with Antioxidant Activity in Cyphostemma auriculatum Roxb. Research Journal of Pharmacy and Technology. 2025;18(9):4047-4. doi: 10.52711/0974-360X.2025.00581 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2025-18-9-1
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