Author(s):
Zh. Abirbekkyzy, N.A. Zamanbekov, P. Sobieсh, N.K. Kobdikova, Sh.B. Turzhigitova, S.T. Nussupova, Zh.I. Kaziyev, M. Baimurzayeva, A.A. Zhylgeldiyeva, A.B. Myrzhiyeva
Email(s):
zamanbekov.nurtleu@mail.ru , turzigitova@mail.ru
DOI:
10.52711/0974-360X.2026.00087 
Address:
Zh. Abirbekkyzy1, N.A. Zamanbekov1*, P. Sobieсh2, N.K. Kobdikova1, Sh.B. Turzhigitova1*, S.T. Nussupova1, Zh.I. Kaziyev1, M. Baimurzayeva1, A.A. Zhylgeldiyeva1, A.B. Myrzhiyeva1
1Kazakh National Agrarian Research University, 8 Abay Ave., Almaty, 050010, Kazakhstan.
2University of Warmia and Masuria, 2 Okzapowski Str., Olsztyn, 10 - 719, Poland.
*Corresponding Author
Published In:
Volume - 19,
Issue - 2,
Year - 2026
ABSTRACT:
The most acute problem in animal husbandry is the high incidence of dyspepsia in newborn calves. Therapeutic and preventive measures aimed at preventing gastrointestinal diseases should be based on data on the course of immunological processes in young animals since animal resistance largely depends on the state of cellular and humoral factors of nonspecific resistance. The research data indicate the stimulating effect of the manufactured phytopreparations on the cellular and humoral defense mechanisms in calves. Under the influence of phytopreparations, concentrations of lysozyme, bactericidal, complementary, and beta-lysine activity of blood serum, as well as indicators of phagocytic activity of blood cells, significantly increase. The most effective form of exposure is the use of alcohol extracts. The patterns in positive changes in the humoral and cellular defense mechanisms of the body suggest that calves with dyspepsia have an immunodeficiency condition accompanied by an imbalance of the immune system. Dyspepsia of newborn calves causes significant losses to farms. Unfortunately, the traditional methods of treating dyspepsia in young animals used in veterinary practice do not always give the desired therapeutic effect. Therefore, the main purpose of this work was the use of phytopreparations to treat and prevent dyspepsia in calves. The results reliably indicate the high therapeutic and preventive effectiveness of the manufactured phytopreparations. The preventive effectiveness and survival rate of calves from the use of a complex plant extract was 100%, whereas in the control group, it was only 65%. High therapeutic effectiveness was also obtained from the use of the complex plant extract, where the effectiveness was 100% compared to 70% of the control group. Phytopreparations, along with a pronounced therapeutic and preventive effect, have a pronounced stimulating effect, as evidenced by a significant increase in the average daily and absolute weight gain. The complex extract increases the average daily increase in body weight compared to the control group by 21.4% and the absolute increase by 37.2%. The main effect of the manufactured phytopreparations in the form of infusions and extracts is directed toward the biocorrection and bionormalization of metabolic processes in calves with dyspepsia.
Cite this article:
Zh. Abirbekkyzy, N.A. Zamanbekov, P. Sobieсh, N.K. Kobdikova, Sh.B. Turzhigitova, S.T. Nussupova, Zh.I. Kaziyev, M. Baimurzayeva, A.A. Zhylgeldiyeva, A.B. Myrzhiyeva. Indicators of Nonspecific Resistance and the Comparative Therapeutic and Preventive effectiveness of Phytopreparations for Dyspepsia in Calves. Research Journal of Pharmacy and Technology. 2026;19(2):594-4. doi: 10.52711/0974-360X.2026.00087
Cite(Electronic):
Zh. Abirbekkyzy, N.A. Zamanbekov, P. Sobieсh, N.K. Kobdikova, Sh.B. Turzhigitova, S.T. Nussupova, Zh.I. Kaziyev, M. Baimurzayeva, A.A. Zhylgeldiyeva, A.B. Myrzhiyeva. Indicators of Nonspecific Resistance and the Comparative Therapeutic and Preventive effectiveness of Phytopreparations for Dyspepsia in Calves. Research Journal of Pharmacy and Technology. 2026;19(2):594-4. doi: 10.52711/0974-360X.2026.00087 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2026-19-2-16
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