Author(s):
Fitrya Fitrya, Elfita Elfita, Julinar Julinar, Reza Fariza, Bunga Tarisha Haq, Wifa Rahmayanti, Julia Sindy Pratama
Email(s):
fitrya@unsri.ac.id
DOI:
10.52711/0974-360X.2026.00160 
Address:
Fitrya Fitrya1*, Elfita Elfita2, Julinar Julinar2, Reza Fariza1, Bunga Tarisha Haq1, Wifa Rahmayanti1, Julia Sindy Pratama1
1Department of Pharmacy, Faculty of Mathematics and Natural Science, Sriwijaya University.
2Department of Chemistry, Faculty of Mathematics and Natural Science, Sriwijaya University.
*Corresponding Author
Published In:
Volume - 19,
Issue - 3,
Year - 2026
ABSTRACT:
Mango ginger (Curcuma amada Roxb.) and Black turmeric (Curcuma aeruginosa Roxb.) are species of Curcuma commonly used as raw materials in traditional herbal medicine (jamu). The curcumin and flavonoid content in these plants are suitable for treating inflammation-related diseases, including gastric ulcers. This research aimed to determine the potential of ethanol extracts from Mango ginger (ERTM) and Black turmeric (ERTI) in protecting against ethanol-induced gastric ulcers in rats. The animals were pre-treated with ERTM and ERTI for two weeks and induced with an ulcer using absolute ethanol. The extent of the extract’s protective effect was evaluated based on the biochemical parameters of gastric fluid and histological analysis of the gastric organ. The data were compared to the gastric contents of rats without pre-treatment. The results showed that the effectiveness of ERTM and ERTI in protecting the gastric from ulcers was approximately equivalent to omeprazole as a standard drug. Ethanol extract of C. amada and C. aeruginosa showed potential as gastroprotective agents and could be developed as antiulcer herbal medicines.
Cite this article:
Fitrya Fitrya, Elfita Elfita, Julinar Julinar, Reza Fariza, Bunga Tarisha Haq, Wifa Rahmayanti, Julia Sindy Pratama. Antiulcer Activity of Curcuma amada Roxb. and Curcuma aeruginosa Roxb. Ethanol Extract in Rats Mode of Gastric Ulcer: Biochemical and Histological Analysis. Research Journal Pharmacy and Technology. 2026;19(3):1130-6. doi: 10.52711/0974-360X.2026.00160
Cite(Electronic):
Fitrya Fitrya, Elfita Elfita, Julinar Julinar, Reza Fariza, Bunga Tarisha Haq, Wifa Rahmayanti, Julia Sindy Pratama. Antiulcer Activity of Curcuma amada Roxb. and Curcuma aeruginosa Roxb. Ethanol Extract in Rats Mode of Gastric Ulcer: Biochemical and Histological Analysis. Research Journal Pharmacy and Technology. 2026;19(3):1130-6. doi: 10.52711/0974-360X.2026.00160 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2026-19-3-21
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