Author(s):
Maha N Abu Hajleh, Ali Al-Samydai, Hany Akeel Al-hussaniy, Daliah Yousef Iqtait, Hala Younis Zainee, Mohamed Mansor
Email(s):
hany_akeel2000@yahoo.com
DOI:
10.52711/0974-360X.2026.00266 
Address:
Maha N Abu Hajleh1, Ali Al-Samydai2, Hany Akeel Al-hussaniy3, Daliah Yousef Iqtait2, Hala Younis Zainee4, Mohamed Mansor5
1Department of Cosmetic Science, Pharmacological and Diagnostic Research Centre, Faculty of Allied Medical Sciences, Al-Ahliyya Amman University, Amman, 19328, Jordan.
2Pharmacological and Diagnostic Research Center, Faculty of Pharmacy Al-Ahliyya Amman University, Amman, Jordan.
3Iraqi Medical Research Center, Baghdad, Iraq.
4Department of Clinical Pharmacy, College of Pharmacy, Al-Zahraa University for Women, Karbala, Iraq.
5Department of Pharmacology, College of Pharmacy, Misurata University, Misurata, Libya.
*Corresponding Author
Published In:
Volume - 19,
Issue - 4,
Year - 2026
ABSTRACT:
Mucinous ovarian cancer (MOC) represents a rare and distinct subtype of epithelial ovarian cancer characterized by the presence of mucin-producing cancer cells. Recent advancements have deepened our understanding of its unique molecular and clinical features, aiding in improved diagnosis and personalized treatment strategies. This review aims to summarize the latest updates in the epidemiology, pathogenesis, diagnostic methods, and therapeutic approaches for MOC. Epidemiological studies indicate a lower incidence of MOC compared to other ovarian cancers, but with unique genetic and molecular signatures that distinguish it from other subtypes. Recent findings highlight the importance of molecular profiling, which reveals frequent mutations in KRAS, TP53, and other genes, offering potential targets for therapy. Diagnostic advances, including refined imaging techniques and biomarker development, enhance early detection and accurate classification. Therapeutically, surgery remains the cornerstone, but emerging targeted therapies and immunotherapies show promise in managing advanced or recurrent cases. This review also discusses ongoing clinical trials and future directions, emphasizing the need for continued research to optimize outcomes for patients with MOC.
Cite this article:
Maha N Abu Hajleh, Ali Al-Samydai, Hany Akeel Al-hussaniy, Daliah Yousef Iqtait, Hala Younis Zainee, Mohamed Mansor. Mucinous Ovarian Cancer: Current Trends in Epidemiology, Pathogenesis, Diagnostic Methods and Therapeutic Approaches. Research Journal of Pharmacy and Technology. 2026;19(4):1852-8. doi: 10.52711/0974-360X.2026.00266
Cite(Electronic):
Maha N Abu Hajleh, Ali Al-Samydai, Hany Akeel Al-hussaniy, Daliah Yousef Iqtait, Hala Younis Zainee, Mohamed Mansor. Mucinous Ovarian Cancer: Current Trends in Epidemiology, Pathogenesis, Diagnostic Methods and Therapeutic Approaches. Research Journal of Pharmacy and Technology. 2026;19(4):1852-8. doi: 10.52711/0974-360X.2026.00266 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2026-19-4-55
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