Author(s):
Sukmayati Alegantina, Efriwati Efriwati, Ani Isnawati, Nanang Yunarto, Ariyani Noviantari, Maratu Soleha, Lucie Widowati, Dian Sundari, Suharmiati Suharmiati, Ifa Manzila, Putri Reno Intan
Email(s):
sukm004@brin.go.id , efri003@brin.go.id , anii001@brin.go.id
DOI:
10.52711/0974-360X.2026.00294 
Address:
Sukmayati Alegantina1, Efriwati Efriwati2, Ani Isnawati3, Nanang Yunarto4, Ariyani Noviantari5, Maratu Soleha6, Lucie Widowati7, Dian Sundari8, Suharmiati Suharmiati9, Ifa Manzila10, Putri Reno Intan11
1Research Center for Pharmaceutical Ingredients and Traditional Medicine, Research Organization for Health, National Research and Innovation Agency, Bogor, Indonesia.
2Research Center for Public Health and Nutrition, Research Organization for Health, National Research and Innovation Agency, Bogor, Indonesia.
3Research Center for Pharmaceutical Ingredients and Traditional Medicine, Research Organization for Health, National Research and Innovation Agency, Bogor, Indonesia.
4STIKES Widya Dharma Husada, Tangerang, Indonesia.
5Center for Biomedical Research, Research Organization for Health, National Research and Innovation Agency, Bogor, Indonesia.
6Research Center for Pharmaceutical Ingredients and Traditional Medicine, Research Organization for Health, National Research and In
Published In:
Volume - 19,
Issue - 5,
Year - 2026
ABSTRACT:
This study aimed to determine the levels of rutin, quercetin, myricetin, and kaempferol in the ethanol extracts of Sauropus androgynus, Moringa oleifera Lam, and Coleus amboinicus Lour leaves, and to evaluate their potential as galactagogue agents to enhance breast milk production in support of sustainable exclusive breastfeeding practices. Extraction of each plant was carried out using percolation method with 70% ethanol as solvent, and analysis of the galactagogue compounds was performed using High-Performance Liquid Chromatography (HPLC). The results showed that the ethanol extracts of S. androgynus, M. oleifera Lam, and C. amboinicus Lour leaves contained rutin, quercetin, myricetin, and kaempferol, with myricetin being the most abundant compound among the three extracts. The consumption of rutin, quercetin, myricetin, and kaempferol in the ethanol extracts of S. androgynus, M. oleifera Lam, and C. amboinicus Lour leaves may help increase breast milk production and support the continuation of breastfeeding and exclusive breastfeeding. Therefore, the ethanol extracts of S. androgynus, M. oleifera Lam, and C. amboinicus Lour leaves have potential to be formulated as nutritional sources for pregnant and breastfeeding women to maintain and enhance the sustainability of breastfeeding and exclusive breastfeeding practices. However, further research is required to confirm safety and efficacy of these ethanol extracts.
Cite this article:
Sukmayati Alegantina, Efriwati Efriwati, Ani Isnawati, Nanang Yunarto, Ariyani Noviantari, Maratu Soleha, Lucie Widowati, Dian Sundari, Suharmiati Suharmiati, Ifa Manzila, Putri Reno Intan. Research Journal Pharmacy and Technology. 2026;19(5):2052-8. doi: 10.52711/0974-360X.2026.00294
Cite(Electronic):
Sukmayati Alegantina, Efriwati Efriwati, Ani Isnawati, Nanang Yunarto, Ariyani Noviantari, Maratu Soleha, Lucie Widowati, Dian Sundari, Suharmiati Suharmiati, Ifa Manzila, Putri Reno Intan. Research Journal Pharmacy and Technology. 2026;19(5):2052-8. doi: 10.52711/0974-360X.2026.00294 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2026-19-5-15
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